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I've had acne since age 12 but it had settled by the time I hit my twenties. I was then only getting the occasional small pimple that was manageable and I had even stopped using benzoyl peroxide washes for the last two years.

Now I'm 26 and I've broken out with the worst nodular and cystic inflammatory acne that I've ever had.

Saw a dermatologist and he put me on oral erythromycin initially for 4 weeks and now been on epiduo for the last two weeks until I can get my liver cleared by a liver specialist before I start isotretinoin.

The acne got somewhat better with erythromycin but still continued to breakout with large nodules although I found the redness was less. I had to stop the antibiotics eventually because it was making my liver tests worse and so was put on epiduo. The first week was great but now into week two I have broken out with about six or seven nodules and cysts all around my chin and near and on my upper lips. It hurts to move my mouth and it's terribly embarrassing and takes a great deal to go to work to show my face.

I'm worried that when I start isotretinoin in 2 weeks time the initial break out is going to be just as bad if not worse.

Will the break out be milder now that I've been on antibiotics for a month and also epiduo for a month?

Anyone have any experience with this?

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I don't have a definite answer for you but from my experience...

I would stop taking whatever you are taking now (epiduo)

The initial breakout is so... how do I put this...

It's going to happen, so, why does it matter what you attribute it to...

Could be the potency of the accutane, your past medicines, hormone fluctuations, stress... And if it is past medicine, it's not like you can do anything about it anyways now so why worry?

Just let it ride its course. It totally sucks, I know. And I wish I had a better answer for you. I am just telling you from my experience.

Good luck. I am in week two of Accutane.

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I guess your right Dani....it'll probably be better if I accept the fact that the breakout is going to happen; nonetheless I was hoping to get lucky and have a less bumpy course :)

It's nice to be in control of things but acne doesn't always give you that option. So far everything I've tried to take control has failed me and I'm really hoping accutane will work.

I guess you just have to ride it out and continue to hope for clearer skin one day! For the moment I hate having to force myself to get out of bed every morning to be judged by every person looking at my face; I'm hoping I'll get used to this!

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Oiltanka, i had quite an interesting experience today. I was in the clinic getting my blood work done to see if i can go on Claravis (generic accutaine) and i realized that no one was paying attention to me (even the little kids who tend to notice everything). As i continued to walk around and take the subway, it was the same thing! I tend to get myself worked up over my acne and i end up being the only one stressed to the max and depressed to boot. As earlier posters said, don't think too much about the initial outbreak as it will happen if you think about (and stress/freak out) or not. I have been on accutaine a few times before (held of acne for 2 yrs a piece) and from what i recall, the initial outbreak sucked but i tried not to make it the highlight of my day - hope this helps!

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For the moment I hate having to force myself to get out of bed every morning to be judged by every person looking at my face; I'm hoping I'll get used to this!

TOTALLY know the feeling!

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I guess you just have to ride it out and continue to hope for clearer skin one day! For the moment I hate having to force myself to get out of bed every morning to be judged by every person looking at my face; I'm hoping I'll get used to this!

YES. And when you talk to people, their eyes jump around to your pimples, not your eyes. It sucks.

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