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2 hours ago, SCOTT242 said:
FYI I am retesting for yeast this month. I'll post when I get results next month. I tested high for yeast in 2014 (attached). Took a tincture to fix but never retested and didn't feel any different. The longest stretch of me feeling good was in 2012 when I took a supplement for h pylori and yeast (first stool test). Lasted about 2 weeks. Notice the resistance my fungi has to wormwood. 
 
Looking forward to seeing your results. Interesting that the test indicates the fungus is resistant to wormwood.
I would personally try taking it regardless to gauge symptoms. It's probably the strongest compound I know of besides Argentyn.
I would also take chlorine dioxide every hour of the day for about a month to see how that affects you as well. (Get up to around 24 drops per day). Lastly, you should research turpentine. It's excellent for fungal infections.

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For anyone who doesn't already know -high  LDL colesterol is one sign of inflamation.
Inflammation is when the immune system over reacts for any given reason,

Immune cells are mostly controlled in the gut and colon.

So gut health is important for immune health,

autoimmune disease develops when you immune system attacks healthy cells.

This might not be quite right but you get the idea - as you are all discussing, gut health is essential.

On 5/14/2016 at 7:55 PM, guitarman01 said:

You guys know this guy? has  the whole wheel house of accutane sides.he has had a shit load of test done if you want to cross check. he goes by Duul
http://www.curezone.org/forums/am.asp?i=2226800

Accutane woke me up in more ways than one....

I originally took Accutane for Severe Scalp Acne/Back Acne/Oily Skin Large Pores, which was "fixed" however...

As a fortunate side effect of taking Accutane in 2009.....

Accutane caused my cerebellar tonsils to shrink, recede OR it adjusted the skull causing my Arnold-Chiari Malformation Type 1

to go away.

From my radiologist scan in 2006, before accutane:

"Multiplanar MRI of the brain reveals the cerebellar tonsils to extend 7mm inferior to the foramen magnum to the level of the posterior arch of C1. Cine CSF Flow studies showed the flow dorsal to the cerebellar tonsils is dampened on all three series"

In 2011 after accutane, my radiologist said I had no more Arnold-Chiari Malformation.

This is not heard of before, this condition can ONLY BE FIXED VIA BRAIN DECOMPRESSION SURGERY.

I am now fixed of my symptoms which included:

-dizziness

-loss of consciousness when bending neck backward or body is upside down

-major headaches and migraines

-chronic fatigue

-leg numbness / falling asleep constantly

HOWEVER: For people that did not have my condition, this is living proof that Accutane makes full physical contact with your brain. There is no debate, this ends it. So you take your risks of acne versus brain damage. Even though it helped an existing condition of mine that I wasn't expecting. What will it do to you?

I quit the drug early because of Knee / Back Pain, Constipation, and Severe Depression and Suicidal thoughts.

When I took Accutane:

Age: 19

Weight: 190

Height: 5'9

Brand: Clavaris

Dose: 40mg twice a day morning and night = 80mg total.

Took for two months before stopping due to side effects.

My Side Effects from Accutane as of December 2014:

-Dry Skin

-Dry Thinning Hair

-Hair Loss ( on and off)

- Changes to Hair Texture: My hair all over my body turn Curly, causing ingrown hair issues more than ever.

-Dry Eyes (sometimes they are in the way, my eyes are never white - always some pinkness or eye irritation)

-Dry Lips

-Eye floaters

- Night Vision reduced (visual snow, Blacks are fuzzy even during day time)

-Older than my age look

- Light Sensitivy / After image burn in easily

-Skin tone is more pale white, hardly can get a tan for some reason.

- Changes in Body Temperature, Sometimes feet are ice cold, other parts of my body are warm.

-Eyes: Staring at a computer screen for to long I see flicker rate bars on my monitor (no joke)

-Rectal Bleeding

-Hemorrhoids (recently have these removed via Banding, my bowel movements have improved 90%, no more bleeding)

-Constipation

- Receeding Gums (teeth sensitive as a result)

- TMJ / Jaw clicking (hurts to yawn sometimes)

- Disc Bulges / Low and Mid back pain. (the biggest side effect, the reason I was able to qualify for Medical MJ)

- Cracking joints such as Knees and thumbs. (loud knee cracks, thumbs always want to crack)

- Low Libido

- Changes in Erection Quality (less hard)

-Penis Head can have dryness (fixed with jojoba oil)

- Lack of Morning Erections (fixed when not masturbating for a week or two)

-Depression (probably because I am dealing with all the above)

-Lack of Dreams (fixed with small supplementation of 1mg of Melatonin)

-Dry Crusty Mucus inside of Nose

-Hand Ecezma, Arm Ecezma, really bad in the winter. (hemp salve works great to moisturize)

-Dryness around Nostrils.

-Dryness patches one or two small ones on beard growth areas.

- Lips always chapped. This might be permanent as no oils have worked yet. Chap stick WILL make it worse.

Tests Done to diagnose side effects:

-Telomeres Tested through SpectraCell Labs in Houston, TX: The Telomeres are shorter. I am 25 Year Old however, the read out says I am roughly 30 Years old. (telomere shortening confirmed? Epigentic Changes?!) http://www.spectrace...ics-intro-page/

-Tested MicroNutrient deficiencies. Which said I was low in Vitamin C, Alpha Lipoic Acid, Molybdenum. For vitamin A it said I had normal levels.

-Tested Semen Analysis: I am fine, I am potent with 130 million sperm count, everything is fine there.

-Tested Ultrasound of Prostate: I am fine there.

-Tested Adrenal Cortisol: Very Low Cortisol levels upon rising, ok mid day then drop at night.

-MRI of Brain done for an issue I had before accutane, however nothing bad was found there.

-General bloodwork came back normal, liver bloodwork normal.

-Tested blood for testosterone total and estrogen. Total Testosterone is 600 (I am Age 25) Estrogen was HIGH at 180 points need to get that down by 70 points.

-Tested the Stool: No H. Pylori Bacteria Found, No Celiac Disease, No Parasites - Beneficial Bactera was OK. Probiotics suggested for IBS Symptoms.

-Heavy Metal Test done: No heavy metals, copper levels normal. All levels normal.

-Urine Tests are fine / clean.

-Bone Marrow Density tested: I'm fine, perfect density.

-Growth Hormone tested: I am fine, nothing out of place there.

What I have done so far to help side effects:

-30 Day Juice Fast (celery, apple, kale, cucumber, ginger, tumeric, parsley, cilantro, basil, mint)

-Use a masticating juicer, slow turning, low heat, doesn't kill as many enzymes, more juice yield.

-Topical Cayanne Pepper for Hair Growth

-Avoid Alcohol

-Hemp Seed Oil

-Medical Cannabis Edibles, Medical Cannabis Bud (big improvement in erections, brain chemistry and depression)

- The Master Cleanse 15 Day Fast (Cayanne, Lemons, Maple Syrup)

-Colonics (total is six now)

-Salt Water Flush

-Abstraining from Vitamin A

-$10,000+ dollars on Supplements from Anti-aging Reservatol to Nootropics (brain supplements)

-MRI of spine showing the Disc Bulges

-Ultra sound of abdomen showing no inflammation.

-Colonscopy revealed three Hemmroids which was causing my IBS and Rectal Bleeding, these were banded. IBS has improved by 50%

-Endoscopy revealed Grade B erosive esophogus from Acid Reflux. I believe this was caused by lack of muscle tension in my stomach region.

Still to do:

-Hair Analysis Test

-MPOD Eye test (checks for eye protein levels)

-Rick Simpson Oil (hard to find, probably have to make my own)

-Liver Flush

-Kidney Flush

-Gallbladder Flush

-IGF-1 Injections

-B12 Injections

-HGH Injections

-TRT Injections

- Hulda Clark Zapper

Final Thoughts:

I hope everyone gets well. Our health WAS robbed from us. The cure to all this corruption on Earth is TRUTH.

We are being poisoned in more ways than one. And Accutane woke me up.

---------------------------------------

Pictures Below of my Brain / Neck MRI:

For pictures of my MRI go to: acne.---org



 

more glands being damaged - pineal gland, how many others can't recall their dreams?

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Have any of you guys tried the atkins diet?

I will be doing a cyclic ketogenic diet while gymming for the next 3 months or so, while monitoring my decreasing body fat% (hoping to reduce it from the curent ~20% to about 8%) to see whether it makes a noticeable difference to my health.

I had also just ordered a bunch of supplements from iherb, after scanning through the information I derived from this thread. I mainly ordered supps that are antagonizing/competitive towards Vit A in the system. (Taurine, VitD +K2, Magnesium, Copper).

Yup, so my strategy is to theoretically decrease my body's storage capacity for Vit A, while reinforcing its ability to get them out of my system.

***
As I mentioned earlier, my dose of accutane was quite high at 80mg/day for 9 months non-stop.
I do also get candida overgrowth issue, but I would say it's under control, and hadn't really been too much of a problem to me. A healthy gut system should prevent candida overgrowth. This could be due to my diet. I eat healthy, my meals contains no processed food like hotdogs or frozen fish fillet, not even biscuits or candies, no sugar. Basically, no sugar and no funny chemicals that you find in most processed foods nowadays. I do not drink soda. But of course, sometimes(like once in 3 months), I give into temptation and do eat a little bit of these junk foods, and I will almost definately get an acne or 2 within the next 2 days.

When I do get candida overgrowth, I make light & diluted apple cider vinegar drink. Just about 5-10 drops of ACV into a cup of water for about 3 times a day, and it seems to help with clearing the overgrowth. I do not sweeten these drink with honey or sugar.

I have a came across articles online regarding reinforcing the repair of your gut linings as a longer term solution to these gut issues. Bone broths and gelatin seems to be highly recommended for gut lining repair. Maybe you guys who are facing candida overgrowth issues can add these to your regime. These are not supplements, they are normal food that you can take during meals or as desserts.

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Everyone should get homocystein levels tested.    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248518/

B12 and folic acid should also be tested, I know many test B12 and it comes back ok, but this article shows that
you can have raised homocysteine but still have normal range B12.

http://www.lifeextension.com/protocols/heart-circulatory/homocysteine-reduction/Page-01

This article about is about lowering homocysteine  and guess what helps?

The main supplement is B12 and folic acid as we al know but Taurine, choline and SAMe all help as well.

Is this why so many find Taurine helps.

The reason this should be taken seriously is because it is degenerative.
Would be interested to hear from anyone who has tested for raised homocysteine.

18 minutes ago, HealthConscious said:

Have any of you guys tried the atkins diet?

I will be doing a cyclic ketogenic diet while gymming for the next 3 months or so, while monitoring my decreasing body fat% (hoping to reduce it from the curent ~20% to about 8%) to see whether it makes a noticeable difference to my health.

I had also just ordered a bunch of supplements from iherb, after scanning through the information I derived from this thread. I mainly ordered supps that are antagonizing/competitive towards Vit A in the system. (Taurine, VitD +K2, Magnesium, Copper).

Yup, so my strategy is to theoretically decrease my body's storage capacity for Vit A, while reinforcing its ability to get them out of my system.

***
As I mentioned earlier, my dose of accutane was quite high at 80mg/day for 9 months non-stop.
I do also get candida overgrowth issue, but I would say it's under control, and hadn't really been too much of a problem to me. A healthy gut system should prevent candida overgrowth. This could be due to my diet. I eat healthy, my meals contains no processed food like hotdogs or frozen fish fillet, not even biscuits or candies, no sugar. Basically, no sugar and no funny chemicals that you find in most processed foods nowadays. I do not drink soda. But of course, sometimes(like once in 3 months), I give into temptation and do eat a little bit of these junk foods, and I will almost definately get an acne or 2 within the next 2 days.

When I do get candida overgrowth, I make light & diluted apple cider vinegar drink. Just about 5-10 drops of ACV into a cup of water for about 3 times a day, and it seems to help with clearing the overgrowth. I do not sweeten these drink with honey or sugar.

I have a came across articles online regarding reinforcing the repair of your gut linings as a longer term solution to these gut issues. Bone broths and gelatin seems to be highly recommended for gut lining repair. Maybe you guys who are facing candida overgrowth issues can add these to your regime. These are not supplements, they are normal food that you can take during meals or as desserts.

Where are you from? - 3am in England lol.  Those supplements look ok but you should get tested first and include Vit D deficiency alongside HCY, B12, folate and  folic acid. Get as much tested as possible really but definitely the ones mentioned.

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I'm from Singapore.

I too would like to get myself tested for these, but the costs of these tests are crazy in Singapore. I am currently looking to sign up for a rather comprehensive hormone screening though.

Some of the items in the package that seems to be of special concern in this community includes includes:

  • Full hormone tests inclusive of insulin, cortisol, insulin-like growth factor 1
  • Detailed thyroid analysis - TSH, T3 and T4
  • Hormonal study (DHEA, LH, FSH)
  • Detailed kidney function test
  • Detailed liver function test
  • Male anti-aging screen - testosterone, free androgen index, sex hormone binding globulin
  • Cardiovascular risk - HSCRP
  • Inflammatory screen (HBA1C, homocysteine, lipoprotein A)
  • Vitamin D level and B12
  • Nutritional screen - folate and ferritin
This package is gonna cost me near 600USD. Any advice if this package is comprehensive enough for post-accutane users?
 

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On 14 May 2016 at 0:03 PM, comishcf said:

Hi everyone,

I haven't posted in a really long time but I have tried out some of the things you have been talking about and have had good success with them, namely taurine and a vitamin d3 supplement (which I was originally prescribed by a doctor for mono and have used ever since). I by no means think that what I'm about to talk about is a cure, but I noticed that someone posted about black walnuts a little while back as a means for managing the side effects of whatever we have going on and this is something that has been included in a supplement that I have been taking with good success for the past year.

Initially, I thought that the problems I had been experiencing were due to allergies and inflammation of the gut set on by accutane. To combat this, I started eating a lot of blueberries, blackberries, raspberries, and strawberries (mainly in the form of protein smoothies) and went to a doctor who recommended a supplement called "GI Microb-X" by Designs for Health. I hope this doesn't sound like I'm trying to sell a product because I'm absolutely not. However, this supplement in combination with the berries have actually been great for me for remedying bad side effects (depression, dry skin, basically everything that has been mentioned). The reason why I am bringing this up is because GI Microb-X has 50 mg of black walnuts in it. Here is the full list of ingredients:

200 mg Tribulus Extract
150 mg Magnesium Caprylate
100 mg Berberine sulfate
100 mg Grapefruit extract
50 mg Barberry extract
50 mg Bearberry extract
50 mg Black walnut powder
15 mg artemisinin

I have been following tryingtohelp specifically for a while now, and have to give a specific shout out to you because of how awesome and on top of things you have been. And honestly, the taurine has helped dramatically (taking 2000 mg a day) so thank you for that. I have yet to start with copper because I haven't been tested for it but that looks promising too. 

Anyways I hope this bit of info helps. The supplements are quite expensive but I truly believe they have helped mitigate symptoms in combination with the berries, as both of these are proven to attack inflammation. For those of you that are looking for some sort of relief, I believe that these things have done that for me. That being said, its absolutely not the cure just a temporary measure (hopefully).


How did GI Microb- X help with your dryness??

Which part of this formula specifically do you think might of helped?

I can't get any relief with the dryness post accutane with any supplements!

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10 hours ago, HealthConscious said:

I'm from Singapore.

I too would like to get myself tested for these, but the costs of these tests are crazy in Singapore. I am currently looking to sign up for a rather comprehensive hormone screening though.

Some of the items in the package that seems to be of special concern in this community includes includes:

  • Full hormone tests inclusive of insulin, cortisol, insulin-like growth factor 1
  • Detailed thyroid analysis - TSH, T3 and T4
  • Hormonal study (DHEA, LH, FSH)
  • Detailed kidney function test
  • Detailed liver function test
  • Male anti-aging screen - testosterone, free androgen index, sex hormone binding globulin
  • Cardiovascular risk - HSCRP
  • Inflammatory screen (HBA1C, homocysteine, lipoprotein A)
  • Vitamin D level and B12
  • Nutritional screen - folate and ferritin
This package is gonna cost me near 600USD. Any advice if this package is comprehensive enough for post-accutane users?
 
I don't know your symptoms but I would recommend testing for autoimmune markers. This has been huge in managing my fatigue/joint pain and diet direction (Autoimmune Paleo). The marker my doctor looks at is called ANA - antinuclear antibodies. We have then looked deeper at thyroid peroxidase and thyroglobulin antibodies (high at times). Also did ENA screen which showed high SSA antibodies. This explains my dry eyes when I am not on my A game. I can lower these autoimmune markers (and joint pain/fatigue) by managing lifestyle (diet, stress, sleep...). 

Not an expert but if I had to pick one I think the ANA would show or rule out autoimmune issues which may help direct your recovery.

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http://mthfr.net/elevated-homocysteine-level-or-laboratory-error/2012/03/02/
19 hours ago, hatetane said:

more glands being damaged - pineal gland, how many others can't recall their dreams?

 
 
 

I cannot recall dreams at all anymore. This is most likely due to infection. The body's interferon system strips trytophan out of the cells to prevent bacteria from converting it to niacin to be metabolized to energy.

Things that help me dream again:
using liposomal melatonin before bed (i use douglas labs brand)
zero lights after 8pm (not even red)
plenty of sunlight during the day (no sunglasses use)
drinking cherry juice before bed (has melatonin)
taking B6 before bed (the pathway: link)
take a little niacin before bed (to free up trytophan to produce melatonin instead)
if needing more tryptophan, eat bone broth (the best broths are from pig feet, trust me) & pumpkin seeds

and I've heard great reports from people supplementing with pure sulfur.

@tryingtohelp2014 Didn't you mention that supplementing with copper allowed you to experience lucid dreaming for the first time in years? How is your dreaming now? Did your dream recall improve after one dose of copper?
What copper supplement do you recommend?

18 hours ago, HealthConscious said:

Have any of you guys tried the atkins diet?

I had also just ordered a bunch of supplements from iherb, after scanning through the information I derived from this thread. I mainly ordered supps that are antagonizing/competitive towards Vit A in the system. (Taurine, VitD +K2, Magnesium, Copper).

Yup, so my strategy is to theoretically decrease my body's storage capacity for Vit A, while reinforcing its ability to get them out of my system.

 
 
5

I've not tried that Atkins diet but I have tried a VLC-HF diet with moderate protein (10% protein, 5% carbohydrate, 80-90% lipids).
It makes me feel better energetically but does not heal me. I don't believe it to be a healthy way of eating long-term.
I'd only do it during the Winter from now on to mimic nature. I've now increased my sugar intake to about 20% of total kcals.

Good supplementation strategy. Let us know how it goes. I would personally avoid taking vit D. I wouldn't want soft-tissue calcification. I'd recommend getting out in the sun instead if possible.

16 hours ago, HealthConscious said:

I'm from Singapore.
Getting a hormonal test.

This package is gonna cost me near 600USD. Any advice if this package is comprehensive enough for post-accutane users?
 
 
 
 
Are you sure you want to use $600 on that test? Even if your hormones come back whacky, does it tell you the cause? I'd personally use that money to purchase things that move you towards health.

@hatetane I've had my homocysteine checked. It was 15.1 umol/L. Ref range is <11.4.
More than likely, my local pathology lab did not perform the necessary requirements to ensure that's not an artifically high test.
I'd assume it is most likely in the normal range in actuality. Edited by yetanotheraccutanevictim

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3 hours ago, yetanotheraccutanevictim said:

Good supplementation strategy. Let us know how it goes. I would personally avoid taking vit D. I wouldn't want soft-tissue calcification. I'd recommend getting out in the sun instead if possible.



i disagree.  For whatever reason, we cannot assimilate Vitamin D from the sun like we should... be it from the 13-cis retinoic acid transforming into ATRA in the sebocytes, providing less oil for the vitamin D to be produced... to something in the liver stopping it as well.  http://www.sciencedirect.com/science/article/pii/S0022202X15409649   

so many ways retinoic acid interferes with vitamin D its scary.   half of the symptoms on DUULs list are just obvious Vitamin D problems.

http://onlinelibrary.wiley.com/doi/10.1111/pde.12614/abstract

Candida   https://www.vitamindcouncil.org/vitamin-d-news/vitamin-d-and-yeast-infections-is-there-a-relationship/
Low back pain/joint pain  https://www.vitamindcouncil.org/vitamin-d-news/study-finds-link-between-vitamin-d-deficiency-and-chronic-low-back-pain/
IBS              http://www.medicalnewstoday.com/articles/304361.php
Dry eyes    http://www.doctorslounge.com/index.php/news/pb/61405



thats why the combination of K2 and Mag should help any out of balance calcium with the D3.   the taurine will help it get absorbed.  i think this is a big missing piece.

http://www.healthcentral.com/rheumatoid-arthritis/c/798984/116673/ta/
http://suppversity.blogspot.com/2012/11/health-exercise-quickie-vitamin-d.html

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Guys, thank you so much for your replies.

I think I may sign up for the hormones test after all. As I mentioned earlier, my dosage of accutane was on the high side at 80mg/day for a whooping 9 months. Yet for now, I can't be sure whether I am actually experiencing it's side effects, so I was hoping that these tests could help me confirm whether I share the same common test anomalies as other fellow post-accutaners.

I eat healthy and, over the years, identified foods that seem to make me sick and have been making the conscious effort to avoid them. Some of them are peanuts and almonds(Legumes?). Chocolates(Lecithin + Diary?) too. Too much of them causes the insides of my mouth and my thyroid to swell, plus horrible canker sores. This actually seems to be some sort of autoimmune issue, drawing reference from @SCOTT242signature.

For now, I seem to have

  • High irritability, anxiety, OCD, Misophonia
    • A cortisol level check may shed some light on this for me?
  • Decreased genital sensitivity, almost no libido
    • Not really a big issue for me, but I am very concerned about the possible underlying hormonal causes behind this.
Additionally, the hormones test includes Vitamin D and B12. Soft tissue calcification sounds terrible, so it would be a serendipitous bonus from the hormones test package to get my D levels checked to give me a peace of mind before I start supplementation.

I did take a men's multivitamin for about a year, and during that period I felt great and full of energy, foods that usually gave me problems stopped doing so, and I recovered extremely quickly from flu/nose allergies. So it seems like supplementation does help me. Some stuffs included in this multivit are; vitamin D, E, K, folate, B-12, Magnesium(Low) & Copper(Low), Grape seed extract. I stopped because I was concerned about the megadose of come of the vitamins in it.

Also, something interesting to note is that this multivit contains 200% DV Vitamin A in the form beta-carotene and retinyl palmitate, yet I didn't feel any Vit A toxicity effects from it like I did from trying cod liver oil. Weird huh? Maybve the presence of Vit D helped to balance it.


  Edited by HealthConscious

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2 hours ago, tryingtohelp2014 said:
i disagree.  For whatever reason, we cannot assimilate Vitamin D from the sun like we should... be it from the 13-cis retinoic acid transforming into ATRA in the sebocytes, providing less oil for the vitamin D to be produced... to something in the liver stopping it as well.  http://www.sciencedirect.com/science/article/pii/S0022202X15409649  
 
I'm just warning people based off my own experience and knowledge of vit D's mechanisms. I think I severely calcified MANY of my soft tissues leading to chronic pain by taking vit D supplements. I took micellized (highly absorbable) vit D. I brought my Vitamin D 25 HYDROXY (CALCIDIOL) up from 30.4 ng/mL to 85.2 nb /mL in about 4 months and my pain got worse and worse. I regret ever touching the stuff. We probably do have problems with vit D metabolism but that might make the supplementation even worse. It's incredibly unnatural to obtain our major source of vit D from food. If supplementing regardless of my warnings, I recommend NO MORE than 1000IU daily to bring it up 5 ng/ml per month.

I also suggest people learn the mechanisms for how it works.
This video below will explain how K2, D, and A work synergistically.
link

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2 hours ago, tryingtohelp2014 said:


i disagree.  For whatever reason, we cannot assimilate Vitamin D from the sun like we should... be it from the 13-cis retinoic acid transforming into ATRA in the sebocytes, providing less oil for the vitamin D to be produced... to something in the liver stopping it as well.  http://www.sciencedirect.com/science/article/pii/S0022202X15409649   

so many ways retinoic acid interferes with vitamin D its scary.   half of the symptoms on DUULs list are just obvious Vitamin D problems.

http://onlinelibrary.wiley.com/doi/10.1111/pde.12614/abstract

Candida   https://www.vitamindcouncil.org/vitamin-d-news/vitamin-d-and-yeast-infections-is-there-a-relationship/
Low back pain/joint pain  https://www.vitamindcouncil.org/vitamin-d-news/study-finds-link-between-vitamin-d-deficiency-and-chronic-low-back-pain/
IBS              http://www.medicalnewstoday.com/articles/304361.php
Dry eyes    http://www.doctorslounge.com/index.php/news/pb/61405



thats why the combination of K2 and Mag should help any out of balance calcium with the D3.   the taurine will help it get absorbed.  i think this is a big missing piece.

http://www.healthcentral.com/rheumatoid-arthritis/c/798984/116673/ta/
http://suppversity.blogspot.com/2012/11/health-exercise-quickie-vitamin-d.html

Im still gathering knowledge on Vit D. I was thinking though, why have some doctors put their accutane patients on Vit A when they experience problems during treatment?? ( I haven't heard of any Dr prescribing Vit D!! )

Its kind of like fight fire with fire approach often used in homeopathy!!

We are all looking at different supplements to help overcome our problems but perhaps there is something there in hitting Vit A - perhaps the answer has been staring us in the face all along!?

Please share thoughts on supplementing with Vit A.

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1 hour ago, yetanotheraccutanevictim said:

 

I'm just warning people based off my own experience and knowledge of vit D's mechanisms. I think I severely calcified MANY of my soft tissues leading to chronic pain by taking vit D supplements. I took micellized (highly absorbable) vit D. I brought my Vitamin D 25 HYDROXY (CALCIDIOL) up from 30.4 ng/mL to 85.2 nb /mL in about 4 months and my pain got worse and worse. I regret ever touching the stuff. We probably do have problems with vit D metabolism but that might make the supplementation even worse. It's incredibly unnatural to obtain our major source of vit D from food. If supplementing regardless of my warnings, I recommend NO MORE than 1000IU daily to bring it up 5 ng/ml per month.

I also suggest people learn the mechanisms for how it works.
This video below will explain how K2, D, and A work synergistically.
link
 
when you took the D, did you take any magnesium or K2 with it at the time?     what were you dosing?  in that link, he basically says take K2 to prevent calciification

A 25(OH)D level should also be obtained, as vitamin D deficiency is a common cause of hypercalcemia. Adequate vitamin D replacement will often correct the hypercalcemia; however, vitamin D deficiency may be masking underlying primary hyperparathyroidism. 

it wouldnt make sense that 1000iu would do anything good or bad. its just not enough.   pregnant women need 6600iu a day just to have any vitamin D for milk   its the accutane that causes the high calcium levels in the first place.  it causes calcified ligaments .   and dont say you can get everything from the sun.  my level is 9  and im out in the sun all of the time.

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here is a simple theory of why accutane could alter  the Vitamin D absorption rates even post-tane.  

1. In order for your body to produce Vitamin D from sunlight you need the precursor to be available in the skin to do this.  that precursor is 7-alpha hydroxylase.  

2. accutane disrupts copper ...  upregulated ATP7A, super jacked up ceruloplasmin levels, inverse Vit A/copper liver relationship etc etc  etc.

3. depleted liver copper levels reduce 7-alpha hydroxylase mnra levels 80%

4. low 7-alpha hydroxylase levels lead to Vitamin D dysregulation/lower production?




two paragraphs explaining this below:

http://www.intechopen.com/books/lipid-metabolism/the-role-of-copper-as-a-modifier-of-lipid-metabolism
The majority of absorbed dietary copper is initially delivered to the liver. Hepatocytes utilize copper for their metabolic needs (such as respiration and radical defense); they also synthesize and secrete the major copper containing protein in serum, ceruloplasmin, and prevent copper overload in the body by exporting excess copper via the canalicular membrane into the bile (
Figure 1). These two important functions of hepatocytes (the production of ceruloplasmin and the removal of excess copper) are performed by another transporter, the copper transporting ATPase ATP7B, which is homologous to ATP7A [6, 7]. Inactivation of ATP7B in patients with Wilson’s disease and in animal models is associated with marked copper overload in the liver and pathologic changes including marked lipid dysregulation in the liver and the serum (discussed in the later sections).


In copper deficiency, plasma HDL rich in apolipoprotein E (ApoE) accumulates and total ApoE binding to liver plasma membranes increases (also reported as a reduction in ApoE-free HDL binding). Interestingly, the cholesterol levels in the liver decrease with copper deficiency, despite an overall increase in hepatic cholesterol synthesis [41, 42]. These changes in synthesis, binding properties, and redistribution of lipoproteins suggest some mechanisms through which copper deficiency affects serum cholesterol levels. Thus far, molecular investigations of copper deficiency have identified increased hepatic expression of SREBP1-responsive fatty-acid synthase, along with the increased nuclear localization of the mature SREBP1 transcriptional activator [24]. Changes in the expression of other genes involved in the fatty acid synthesis have not been explored in any significant detail, although the mRNA levels for cholesterol 7-alpha hydroxylase were found decreased by 80%.

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13 hours ago, yetanotheraccutanevictim said:

 

I'm just warning people based off my own experience and knowledge of vit D's mechanisms. I think I severely calcified MANY of my soft tissues leading to chronic pain by taking vit D supplements. I took micellized (highly absorbable) vit D. I brought my Vitamin D 25 HYDROXY (CALCIDIOL) up from 30.4 ng/mL to 85.2 nb /mL in about 4 months and my pain got worse and worse. I regret ever touching the stuff. We probably do have problems with vit D metabolism but that might make the supplementation even worse. It's incredibly unnatural to obtain our major source of vit D from food. If supplementing regardless of my warnings, I recommend NO MORE than 1000IU daily to bring it up 5 ng/ml per month.

I also suggest people learn the mechanisms for how it works.
This video below will explain how K2, D, and A work synergistically.
link

I agree. It just doesn't make sense to ingest vit D. Edited by Accustained

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11 hours ago, TrueJustice said:

Im still gathering knowledge on Vit D. I was thinking though, why have some doctors put their accutane patients on Vit A when they experience problems during treatment?? ( I haven't heard of any Dr prescribing Vit D!! )

Its kind of like fight fire with fire approach often used in homeopathy!!

We are all looking at different supplements to help overcome our problems but perhaps there is something there in hitting Vit A - perhaps the answer has been staring us in the face all along!?

Please share thoughts on supplementing with Vit A.
 

Accutane depletes vitamin A:
link

We're deficient in vit A and toxic in synthetic retinoic acid.

11 hours ago, tryingtohelp2014 said:
 
when you took the D, did you take any magnesium or K2 with it at the time?     what were you dosing?  in that link, he basically says take K2 to prevent calciification

A 25(OH)D level should also be obtained, as vitamin D deficiency is a common cause of hypercalcemia. Adequate vitamin D replacement will often correct the hypercalcemia; however, vitamin D deficiency may be masking underlying primary hyperparathyroidism. 

it wouldnt make sense that 1000iu would do anything good or bad. its just not enough.   pregnant women need 6600iu a day just to have any vitamin D for milk   its the accutane that causes the high calcium levels in the first place.  it causes calcified ligaments .   and dont say you can get everything from the sun.  my level is 9  and im out in the sun all of the time.
 
Yes, I took K2 and LOADS of magnesium while on it as a safety measure. I even was eating homemade sauerkraut made with Kinetic culture (tons of vit K2). It was either the vit D calcifying me or I was building up oxalates in my body by infection or diet. Not entirely sure. For those supplementing vit D, just be smart and monitor your symptomology carefully.

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35 minutes ago, yetanotheraccutanevictim said:

Accutane depletes vitamin A:
link

We're deficient in vit A and toxic in synthetic retinoic acid.

Yes, I took K2 and LOADS of magnesium while on it as a safety measure. I even was eating homemade sauerkraut made with Kinetic culture (tons of vit K2). It was either the vit D calcifying me or I was building up oxalates in my body by infection or diet. Not entirely sure. For those supplementing vit D, just be smart and monitor your symptomology carefully.

exactly how much Vitamin D and K2 were you taking?  did you ever have your calcium levels checked during this time?

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20 minutes ago, tryingtohelp2014 said:

exactly how much Vitamin D and K2 were you taking?  did you ever have your calcium levels checked during this time?
 
 
This was two years ago. I don't remember exact amounts.

This is the vit D I was using: link
I was taking around 5-10 drops per day.

Not sure how much K2 I was taking. But at that time, I did research and found a good amount to take based off the vit D. I used a mix of MK-7 and MK-4.

I did not have my calcium checked during my heavy dosing period, unfortunately.
My calcium before and after the dosing period hovered between 9.6 - 10.2 mg/dL.

EDIT:
Check out my WBCs from over the past 3 years.
Clearly I have an infection:
link Edited by yetanotheraccutanevictim

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4 hours ago, yetanotheraccutanevictim said:

EDIT:
Check out my WBCs from over the past 3 years.
Clearly I have an infection:
link

 Interesting your WBC count dropped and reached its lowest level at the end of accutane.   exactly what i would expect to see.   WBC's go down during a copper deficiency.   youre the third guy to report low WBC.. one of them had a confirmed  deficiency.

http://www.digitalnaturopath.com/cond/C269841.html

(look under nutrients and testing u should order)

Other Possible Signs of Copper Deficiency
Cells unable to make ATP reduce overall physical energy, creating a sense of fatigue. Hormonal imbalances may result as iron builds up in the endocrine system. This can lead to low body temperature, osteoporosis and bone fractures, an irregular heartbeat, a higher risk of coronary artery disease, low white blood cell counts, and a loss of skin pigmentation. Researchers have also reported copper deficiency causes neural and nervous system dysfunction. Copper-replacement therapy has been found to alleviate these symptoms which appear as a B12 deficiency. [3]

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On 5/16/2016 at 8:39 PM, yetanotheraccutanevictim said:

http://mthfr.net/elevated-homocysteine-level-or-laboratory-error/2012/03/02/

I cannot recall dreams at all anymore. This is most likely due to infection. The body's interferon system strips trytophan out of the cells to prevent bacteria from converting it to niacin to be metabolized to energy.

Things that help me dream again:
using liposomal melatonin before bed (i use douglas labs brand)
zero lights after 8pm (not even red)
plenty of sunlight during the day (no sunglasses use)
drinking cherry juice before bed (has melatonin)
taking B6 before bed (the pathway: link)
take a little niacin before bed (to free up trytophan to produce melatonin instead)
if needing more tryptophan, eat bone broth (the best broths are from pig feet, trust me) & pumpkin seeds

and I've heard great reports from people supplementing with pure sulfur.

@tryingtohelp2014 Didn't you mention that supplementing with copper allowed you to experience lucid dreaming for the first time in years? How is your dreaming now? Did your dream recall improve after one dose of copper?
What copper supplement do you recommend?

I've not tried that Atkins diet but I have tried a VLC-HF diet with moderate protein (10% protein, 5% carbohydrate, 80-90% lipids).
It makes me feel better energetically but does not heal me. I don't believe it to be a healthy way of eating long-term.
I'd only do it during the Winter from now on to mimic nature. I've now increased my sugar intake to about 20% of total kcals.

Good supplementation strategy. Let us know how it goes. I would personally avoid taking vit D. I wouldn't want soft-tissue calcification. I'd recommend getting out in the sun instead if possible.

Are you sure you want to use $600 on that test? Even if your hormones come back whacky, does it tell you the cause? I'd personally use that money to purchase things that move you towards health.

@hatetane I've had my homocysteine checked. It was 15.1 umol/L. Ref range is <11.4.
More than likely, my local pathology lab did not perform the necessary requirements to ensure that's not an artifically high test.
I'd assume it is most likely in the normal range in actuality.
Just wondering, no offence but why would you have a test them dismiss it as wrong.
Surly it is worth a re-test.

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In to response for Vit D discussion! I have posted this many times before and not in any way disagreeing  with other studies posted in relation to Vit D and Vit A.

posted this once before on pg. 2 of this thread...Vit A & Vit D compete against each other, they have a important relationship and there are studies that show Accutane depletes Vit D.

Omega-3 fats and other molecules bind to Vitamin A receptors. Same as Vitamin D is also the most important partnership with Vit A and Omega's.

Retinoid, Vit A, Vit D, Thyroid hormones is in a group called the steroid family. This family is known for developing partnerships w/other hormones (such as growth hormones) They all bind to nuclear receptors, meaning they have access to the nucleus, where they influence gene expression.

 

When you have either Vit A or Vit D it almost always does so in partnership with Vit A receptor, which binds vitamin A or the omega-3 fatty acid DHA. In the nucleus of the cell, it sits as judge and jury, deciding which genes are turned on and which are turned off. Vit D and its partners Vit A and DHA (omega 3) are conducting the orchestra.

(book written by James E. Dowd, M.D. from MI Arthritis Institute

It is possible to have calcification or other bone issues from Accutane. It is stated in the side effects. I myself and if sooo after all these years I can re post my results while on and after Accutane my calcium levels were high and I was taking No supplements at the time.

As for Copper and Zinc if you test your levels and are low then great to supplementing, however if you have any type of thyroid issue (like myself) please tread careful. I myself am hyperthyroid and zinc is not the best for me and I have to be careful with Copper also. If your Hypothyroid then they are both need at times in average doses.
However, with that said if you have neurological most neurologist check for copper levels as certain disorders and brain issues can be caused by this or lead to low copper levels.

I also suggest those who have not read about epgentic changes due to Accutane and their studies in relation to many issues that most of us suffers have. If you suffer from brain changes James Crandall Ph.D. did a study and has a great explanation on Accutane and the brain. Yes most of know of Douglas Bremner m.d. studies hired by Liam.

One must remember as I have always said, we all have similar or suffer from the same alignments but we are all made up of different DNA and what works for one may not work for another.

If need be I have no problems posting my numerous labs and doctor visits and naturopathic doctor visits from over the last 7-8 yrs!
.
Someone also mentioned hyperbaric oxygen chamber I have had those done in the past they help, but no cure!

Hope you are all doing well,

Jen

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Here it is right here. Vitamin A causes DNA damage via copper. 
 

Oxidative DNA Damage by Vitamin A and Its Derivative via Superoxide Generation


http://m.jbc.org/content/275/3/2003.full

Experiments using 32P-labeled isolated DNA demonstrated that retinol and retinal caused Cu(II)-mediated DNA damage

Superoxide is produced as a by-product of oxygen metabolism and, if not regulated, causes many types of cell damage
  Edited by guitarman01

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9 minutes ago, oli girl said:

In to response for Vit D discussion! I have posted this many times before and not in any way disagreeing  with other studies posted in relation to Vit D and Vit A.

posted this once before on pg. 2 of this thread...Vit A & Vit D compete against each other, they have a important relationship and there are studies that show Accutane depletes Vit D.

Omega-3 fats and other molecules bind to Vitamin A receptors. Same as Vitamin D is also the most important partnership with Vit A and Omega's.

Retinoid, Vit A, Vit D, Thyroid hormones is in a group called the steroid family. This family is known for developing partnerships w/other hormones (such as growth hormones) They all bind to nuclear receptors, meaning they have access to the nucleus, where they influence gene expression.

 

When you have either Vit A or Vit D it almost always does so in partnership with Vit A receptor, which binds vitamin A or the omega-3 fatty acid DHA. In the nucleus of the cell, it sits as judge and jury, deciding which genes are turned on and which are turned off. Vit D and its partners Vit A and DHA (omega 3) are conducting the orchestra.

(book written by James E. Dowd, M.D. from MI Arthritis Institute

It is possible to have calcification or other bone issues from Accutane. It is stated in the side effects. I myself and if sooo after all these years I can re post my results while on and after Accutane my calcium levels were high and I was taking No supplements at the time.

As for Copper and Zinc if you test your levels and are low then great to supplementing, however if you have any type of thyroid issue (like myself) please tread careful. I myself am hyperthyroid and zinc is not the best for me and I have to be careful with Copper also. If your Hypothyroid then they are both need at times in average doses.
However, with that said if you have neurological most neurologist check for copper levels as certain disorders and brain issues can be caused by this or lead to low copper levels.

I also suggest those who have not read about epgentic changes due to Accutane and their studies in relation to many issues that most of us suffers have. If you suffer from brain changes James Crandall Ph.D. did a study and has a great explanation on Accutane and the brain. Yes most of know of Douglas Bremner m.d. studies hired by Liam.

One must remember as I have always said, we all have similar or suffer from the same alignments but we are all made up of different DNA and what works for one may not work for another.

If need be I have no problems posting my numerous labs and doctor visits and naturopathic doctor visits from over the last 7-8 yrs!
.
Someone also mentioned hyperbaric oxygen chamber I have had those done in the past they help, but no cure!

Hope you are all doing well,

Jen


Excellent post - thank you. But again I ask, why do some doctors put their patients on Vit A during treatment if they experience negative side effects????

I get that accutane is a synthetic version of Vit A, I get that but can someone show me an example of a doctor giving their patients Vit D or even Copper - I'm not seeing any examples of this!!!

Should we investigate taking Vit A again?? I just don't know. Still waiting to see my blood tests on D to see if low before I decide what to try next.

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25 minutes ago, TrueJustice said:

Excellent post - thank you. But again I ask, why do some doctors put their patients on Vit A during treatment if they experience negative side effects????

I get that accutane is a synthetic version of Vit A, I get that but can someone show me an example of a doctor giving their patients Vit D or even Copper - I'm not seeing any examples of this!!!

Should we investigate taking Vit A again?? I just don't know. Still waiting to see my blood tests on D to see if low before I decide what to try next.

TrueJustice - I am not sure if your from the U.S., but here the rx form of Vit D is so different from natural or supplement form.
 

Supplemental vitamin D comes in two forms: ergocalciferol(vitamin D2) and cholecalciferol (vitamin D3).

They have generally been regarded as equivalent and interchangeable,but that notion is based on studies of ricketsprevention in infants conducted seven decades ago.

Recent studies have shown that  vitamin D3 is a more potent formof vitamin D. Vitamin D2 has a shorter shelf life, and its metabolites bind with protein poorly, making it less effective. One unit of cod liver oil (containing vitamin D3) has been shown to be as effective as four units of Viosterol (a medicinal preparation of vitamin D2).

However, the form of vitaminD used in prescriptions in North America is almost invariably vitamin D2.

Basically there are two types of oral vitamin D supplements. The natural ones are D3, and they contain the same vitamin D your body makes when exposed to sunshine. The synthetic ones are vitamin D2, which are sometimes called ergocalciferol.

Once either form of the vitamin is in your body, it needs to be converted to a more active form. Vitamin D3 is converted 500 percent faster than vitamin D2. Interestingly, it was previously thought that the kidney exclusively performed this function.

However, in 1998 Dr. Michael Hollick, the person who discovered activated vitamin D, showed that many other cells in your body can make this conversion, but they use it themselves, and it is only the kidney that makes enough to distribute to the rest of your body.

While there have been no clinical trials to date demonstrating conclusively that D2 prevents fractures, every clinical trial of D3 has shown it does.

However, nearly all the prescription-based supplements contain synthetic vitamin D2, which was first produced in the 1920s through ultraviolet exposure of foods. The process was patented and licensed to drug companies for use in prescription vitamins. In case you didn't know, the vitamin D that is added to milk is NOT D3 but the highly inferior vitamin D2.

The study linked above concluded that "vitamin D2 should no longer be regarded as a nutrient appropriate for supplementation or fortification of foods.

With this being said, if you have a autoimmune disease like me or compromised immune system like most of us who took Accutane then natural form of Vit D, good ole sunshine may not be good enough and supplementing may be necessary. I advised liquid drop organic form.

As for Vit A. I had my retinoid levels tested shortly after Accutane and they were high. For me any foods, products, or supplements with RETINOL form cause many issues for me. I stay far away from Cod Liver Oil etc. I do eat some veggies with beta etc. but it took a long time. Some Accutane suffers have no problem with Beta form.

I do know that some suffers have problems with Omegas and Vit D. Hence my previous post, and also some have been found eventually to have Sarcoid, which one can't ingest Vit D.

I ADVISE NOONE INGEST COD LIVER OIL!!!!!!
Hope this helps!!!!

Jen

Edited by oli girl

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I recently began supplementing with Vitamin A (about 32,000 iu/day), and I feel much improved. My skin has noticeably gotten better. It used to be severely dehydrated after accutane, but it's less so now that I have been using Vitamin A.

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