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heat-shock related protein

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was looking at heat therapy related to scarless healing and thought

this was interestings:

heat-shock related protein: in a nutshell heat causes a "heat shock related protein"

to block tgf-b-1 from forming scars.



Gowthami Putumbaka

Computational Biosciences Program

Arizona State University

Dr.Padmini Komalavilas

Internship Advisor

Center for metabolic biology, School of Life Sciences

Arizona State University

"AZX100 is novel in that a relevant phospho protein motif is directly delivered inside the cell and

modulates downstream events that regulate scar formation. Our results indicate that AZX 100

increases monomeric G actin by depolymerizing actin which disrupts cytoskeleton. Since

disruption of cytoskeleton decreases CTGF expression and prevent excessive scarring, AZX100

may be used as a therapeutic agent for excessive scarring and fibrotic disorders."

a few studies:



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