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third course of accutane: IB?

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Ive been on accutane three times so far (6 months x 3) and have been on minocycline twice (about a year at a time). It looks like I will have to go back on accutane again due to my moderate but stubborn acne (no cysts). I was wondering if you guys who have experience with multiple courses tend to get IBs the second or third time around? Right now, I've been on mino for 4 months and am using Retin-A gel at night in case you think that would reduce the chance of an IB. Also, do you think a lower dose to start with (20mg) would be better at controlling the IB if I get one? Or just prolong it?

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