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why are my eyelids puffy with spironolactone?

This does not sound like a normal reaction and you should definitely call your doctor right away about it. Sorry I can't be of more help, but I've never heard of this before.

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I hadn't thought of it until just now, but since I started taking spiro my eyes haven't been puffy at all!

Another side effect to love!

I agree - you should check with your doctor.

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