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Dear Prudence

Whats the difference between all of these?

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Correct me if I'm wrong, but they're all different types of retinoids, aren't they? Differin has adapalene (mildest retinoid) in it, Tazorac has tazoratene, and Retin A has tretinoin. I think the difference is in how well your skin tolerates each of the retinoids; your skin could totally hate tazoratene but like adapalene.

Also, Differin is milder than both tazoratene and tretinoin.

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Yes they are all retinoids, but with Differin, it does not become unstable over time. What that means is that if you apply Differin in the evenings, you can apply a BP formula 10-15 minutes later and it will enhance (sometimes worsen) your acne regime. The others...become unstable over time. It just depends on their base compound. Retin-A and Tazorac are derivatives of Vitamin-A, and Differin's active ingredient is adapalene.

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