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cosmo24

anyone have irregular blood work?????

Hi, I was just wondering if anyone had irregularties in their blood work? Going into my 2nd month mine came back and showed that I had high colestrol and high liver enzymes(and I am not a heavy drinker...just a few on weekends). My derm up'ed my dose even from 40mg to 60mg then he gave me a diet to follow(and I am not overweight I just eat to much junk I guess) and I am taking milk thistle for my liver but I want to know if anyone else has experienced this??? Please help any tips and/or advice would be greatly appreciated.

THANKS!

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There are several posts about this, along with recommendations for a liver healthy diet.

Caring for Your Liver

Basic Liver Care

Diet and Your Liver

Basic Liver Care

Your liver depends on you to take care of it . . . so it can take care of you. It serves as your body's engine, pantry, refinery, food processor, garbage disposal, and "guardian angel." The trouble is, your liver is a silent partner; when something's wrong it does not complain until the damage is far advanced. So it needs your help every day to keep it healthy and hepatitis-free. To do that, you need to eat a healthy diet, exercise, get lots of fresh air, and avoid things that can cause liver damage.

What does my liver do?

Sadly, people generally have little knowledge of the complexities and importance of the thousands of vital functions their livers perform nonstop.

The liver is about the size of a football – the largest organ in your body. It plays a vital role in regulating life processes. Before you were born, it served as the main organ of blood formation. Now, its primary functions are to refine and detoxify everything you eat, breathe, and absorb through your skin. It is your body's internal chemical power plant, converting nutrients in the food you eat into muscles, energy, hormones, clotting factors and immune factors.

It stores certain vitamins, minerals (including iron) and sugars, regulates fat stores, and controls the production and excretion of cholesterol. The bile, produced by liver cells, helps you to digest your food and absorb important nutrients. It neutralizes and destroys poisonous substances and metabolizes alcohol. It helps you resist infection and removes bacteria from the blood stream, helping you to stay healthy. Arguably, your liver isn't just your silent partner – it's your best friend.

Three things to avoid for liver health:

1 Avoid excessive alcohol.

Most people know that the liver acts as a filter and can be badly damaged by drinking too much alcohol. Liver specialists suggest that more than two drinks a day for men – and more than one drink a day for women – may even be too much for some people.

One of the most remarkable accomplishments of this miraculous organ is its ability to regenerate. (Three quarters of the liver can be removed and it will grow back in the same shape and form within a few weeks!) However, overworking your liver by heavy alcohol consumption can cause liver cells (the "employees" in the power plant) to become permanently damaged or scarred. This is called cirrhosis.

2 Avoid drugs and medicines taken with alcohol.

Medicines – especially the seemingly harmless acetaminophen (the active ingredient in Tylenol and other over-the-counter medications) – should never be taken with alcoholic beverages. Many prescribed and over-the-counter drugs and medicines (including herbal medications) are made up of chemicals that could be potentially hazardous to your precious liver cells, especially taken with alcohol.

If you are ill with a virus or metabolic disorder, liver damage may result from the medications you take. In such cases, you should ask your physician about possible liver cell damage.

3 Avoid environmental pollutants.

Fumes from paint thinners bug sprays, and other aerosol sprays are picked up by the tiny blood vessels in your lungs and carried to your liver where they are detoxified and discharged in your bile. The amount and concentration of those chemicals should be controlled to prevent liver damage. Make certain you have good ventilation, use a mask, cover your skin, and wash off any chemicals you get on your skin with soap and water as soon as possible.

Diet and Your Liver

Overview

Poor nutrition is rarely a cause of liver disease, but good nutrition in the form of a balanced diet, may help liver cells damaged by hepatitis viruses to regenerate, forming new liver cells. Nutrition can be an essential part of treatment. Many chronic liver diseases are associated with malnutrition.

Watch the Protein

To quickly determine your daily protein in grams, divide your weight in pounds by 2. Too much daily protein may cause hepatic encephalopathy (mental confusion). This occurs when the amount of dietary protein is greater than the liver's ability to use the protein. This causes a build up of toxins that can interfere with brain function. Protein is restricted in patients with clinical evidence of encephalopathy. However, controversy exists regarding the type of protein a diet should contain. Vegetable and dairy protein may be tolerated better than meat protein. Medications, such as lactulose and neomycin, may be used to help control hepatitis-related encephalopathy. Due to the body's need for proteins, protein restriction should only be undertaken with a doctor's advice.

Watch the Calories.

Excess calories in the form of carbohydrates can add to liver dysfunction and can cause fat deposits in the liver. No more than 30% of a person's total calories should come from fat because of the danger to the cardiovascular system. To figure out your daily calorie needs, you'll need a minimum of 15 calories a day for each pound you weight. Watch the Salt Good nutrition also helps to maintain the normal fluid and electrolyte balances in the body. Patients with fluid retention and swelling of the abdomen (ascites), or the legs (peripheral edema), may need diets low in salt to avoid sodium retention that contributes to fluid retention. Avoiding foods such as canned soups and vegetables, cold cuts, dairy products, and condiments such as mayonnaise and ketchup can reduce sodium intake. Read food labels carefully as many prepared foods contain large amounts of salt. The best-tasting salt substitute is lemon juice.

Watch Vitamins A and D

Excessive amounts of some vitamins may be an additional source of stress to the liver that must act as a filter for the body. Mega-vitamin supplements, particularly if they contain vitamins A and D, may be harmful. Excess vitamin A is very toxic to the liver.

Beware of Alcohol

You'll need to stop drinking completely to give your liver a break - a chance to heal, a chance to rebuild, a chance for new liver cells to grow. This means avoiding beer, wine, cocktails, champagne, and liquor in any other form. If you continue to drink, your liver will pay the price, and if your doctor is checking your liver function tests, it may be hard to determine if a change in a test means there has been damage to your liver due to the disease itself or because of the alcohol.

Beware of Alcohol and Acetaminophen

Acetominophen is an ingredient in some over-the-counter pain relievers, and is contained in many over-the-counter drugs used for colds or coughs. Taken with alcohol, these products can cause a condition called sudden and severe hepatitis which could cause fatal liver failure. Clearly, you should never combine these two substances. If you have any doubt about what medicines to take simultaneously, ask your doctor.

Beware of "Nutritional Therapies"

Herbal treatments and alternative liver medicines need to undergo rigorous scientific study before they can be recommended. "Natural" or diet treatments and herbal remedies can be quite dangerous. Plants of the Senecio, Crotalaria and Heliotopium families, plus chaparral, germander, comfrey, mistletoe, skullcap, margosa oil, mate tea, Gordolobo yerba tea, pennyroyal, and Jin Blu Huan are all toxic to the liver.

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I have not taken isotretinoin (yet), but I've been doing a lot of reading on the boards and on other sites as I try to figure out if I want to try it or not. I've seen many people say that some of their blood levels were abnormal (especially elevated lipids/cholesterol and sometimes liver enzymes). As long as they don't get too high (as determined by your doctor) then slight elevations are usually reversible and may not indicate a true problem. However, if platelets or white blood cells start dropping, then that may warrant discontinuation of the drug.

I just now found this article that discusses the prevalence of abnormal lab values in patients taking isotretinoin. I thought it might make you feel better and/or give you some perspective.

You can also ask your doctor about it at your next visit or give his office a phone call so that they can put your mind at ease. It's their job! (Or should be at least.)

http:// archderm.ama-assn. org/cgi/reprint/142/8/1016

Hi, I was just wondering if anyone had irregularties in their blood work? Going into my 2nd month mine came back and showed that I had high colestrol and high liver enzymes(and I am not a heavy drinker...just a few on weekends). My derm up'ed my dose even from 40mg to 60mg then he gave me a diet to follow(and I am not overweight I just eat to much junk I guess) and I am taking milk thistle for my liver but I want to know if anyone else has experienced this??? Please help any tips and/or advice would be greatly appreciated.

THANKS!

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Thanks for the response, it really helped! If anyone reading this has any tips or if you have experienced a change in your blood work feel free to share your experience/advice.

THANKS AGAIN

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I have not taken isotretinoin (yet), but I've been doing a lot of reading on the boards and on other sites as I try to figure out if I want to try it or not. I've seen many people say that some of their blood levels were abnormal (especially elevated lipids/cholesterol and sometimes liver enzymes). As long as they don't get too high (as determined by your doctor) then slight elevations are usually reversible and may not indicate a true problem. However, if platelets or white blood cells start dropping, then that may warrant discontinuation of the drug.

I just now found this article that discusses the prevalence of abnormal lab values in patients taking isotretinoin. I thought it might make you feel better and/or give you some perspective.

You can also ask your doctor about it at your next visit or give his office a phone call so that they can put your mind at ease. It's their job! (Or should be at least.)

http:// archderm.ama-assn. org/cgi/reprint/142/8/1016

Hi, I was just wondering if anyone had irregularties in their blood work? Going into my 2nd month mine came back and showed that I had high colestrol and high liver enzymes(and I am not a heavy drinker...just a few on weekends). My derm up'ed my dose even from 40mg to 60mg then he gave me a diet to follow(and I am not overweight I just eat to much junk I guess) and I am taking milk thistle for my liver but I want to know if anyone else has experienced this??? Please help any tips and/or advice would be greatly appreciated.

THANKS!

Thank you soooo much beachkrazd your post really really helped. I will definatly check out that site and I will ask my Dr. about the blood work results I am sure the levels were not to high if he up'ed my dose. Thanks again for all your help!!!

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ive been off for about 1 month on my last month due to stupidity of my doctor and nurses. but i was suposed to be off for only 1 week due to bad liver results.

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Cosmo24- Not sure if your in the U.S., but you can also read directly what Roche says about accutane effecting liver,cholesterol levels. I believe thier information is on page 30,32,33,34.

http://www.rocheusa.com/products/accutane/pi/pdf

Almost all the time Cholesterol levels go back to normal after your course. Also, Wynne posted a good link for liver care.

Good Luck :D

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my readings for my triglycerides (i think that is what it was...?) was about 500 one month ...

we decreased my dosage and it went wayyyy back down.

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I was just looking for this problem...i went for my appointment the other day and my fat lipis/colesterol have gone up, its always been good, so they have lowered my dose from 75mg to 60mg and asked me to watch my diet to try and get it back down.

The only downside is i may have to be on the meds 6 months rather than the 4 months they initially wanted me to take.

I started my third month yesterday.

Michelle

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