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oli girl

'Accutane debate placeholder thread'

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I am willing to create a pinned thread for links to Accutane studies. The thread will be very tightly moderated, though. It won't be a place to debate the studies, simply a reference point.

It's a great idea, but I hope you will check the validity of the studies (whether the journal that published it is credible, etc), because it may be misleading and give wrong information if the links cannot be disputed.

I'm hardly qualified to do that.

If anyone spots a problem with a posted link, here are the options:

-- Start a thread to debate the issue

-- PM a mod

-- Post in the thread to point out the problem ... the post will eventually end up invisible, but hopefully the problem will get sorted out as well.

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is birth control ranked as the top 4th dangerous drug on the market and only 1/100 side effects ever get reported? Don't think so :naughty:

Accutane's rank has no effect on whether or not it works.

Yes, but it clearly shows that you can't compare birth control to accutane

I clearly just did, as they clearly both have possible serious side effects and are clearly both being prescribed for non-life-threatening conditions.

and one is clearly more dangerous than the other. birth control is not listed as top 4 on FDA's database, I am not a woman and do not have first hand knowledge of birth control, but I have researched Accutane so I can only suggest what I know. thank you for your time

I was looking on the FDA website and can't seem to find the list you're referring to. Could you please link me?

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is birth control ranked as the top 4th dangerous drug on the market and only 1/100 side effects ever get reported? Don't think so :naughty:

Accutane's rank has no effect on whether or not it works.

Yes, but it clearly shows that you can't compare birth control to accutane

I clearly just did, as they clearly both have possible serious side effects and are clearly both being prescribed for non-life-threatening conditions.

and one is clearly more dangerous than the other. birth control is not listed as top 4 on FDA's database, I am not a woman and do not have first hand knowledge of birth control, but I have researched Accutane so I can only suggest what I know. thank you for your time

I was looking on the FDA website and can't seem to find the list you're referring to. Could you please link me?

http://www.accutaneaction.com/adr/index.html

http://www.accutaneaction.com/adr/index.html#ranking

http://www.accutaneaction.com/adr/index.html#frequently

http://www.accutaneaction.com/adr/index.html#dechallenge

first link shows all.

Since it was approved by the FDA in 1982, its warning label has been changed more than 50 times because of adverse reactions. The list of side effects and warnings take up seven pages in the newly updated Physician’s Desk Reference. It’s among the top four drugs that attract the most reported adverse drug reactions on the FDA’s database. Due to the incidence of underreporting, the FDA estimates only about 1 to 10 percent of all side effects ever get reported to the agency. Based on this info, one can only imagine about how many serious side effects have occurred because of Accutane that have never been reported to anyone. Even Roche has admitted several years ago that there are over 40,000 Accutane adverse drug reaction reports on the database at their headquarters in Basel, Switzerland. As of today 266 cases of suicide have been reported to be caused by Accutane here in the United States, over 5000 psychiatric adverse drug reactions have been reported to the FDA and remember these probably represent only 1 to 10 percent of the actual number that have occurred. Since 1982, hundreds of deaths other than suicide (strokes, heart attacks, Crohn’s disease, and several other causes) have been recorded in the FDA’s adverse event reporting system. In the year 2007 alone, 430 cases of inflammatory bowel disease and 22 deaths were reported in connection with Accutane.

http://www.druglib.com/adverse-reactions_s...fects/accutane/

Accutane is only one of 3 drugs on the market that comes with a med guide, the other one is thalidomide, and I forget the 3rd.

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is birth control ranked as the top 4th dangerous drug on the market and only 1/100 side effects ever get reported? Don't think so :naughty:

Accutane's rank has no effect on whether or not it works.

Yes, but it clearly shows that you can't compare birth control to accutane

I clearly just did, as they clearly both have possible serious side effects and are clearly both being prescribed for non-life-threatening conditions.

and one is clearly more dangerous than the other. birth control is not listed as top 4 on FDA's database, I am not a woman and do not have first hand knowledge of birth control, but I have researched Accutane so I can only suggest what I know. thank you for your time

I was looking on the FDA website and can't seem to find the list you're referring to. Could you please link me?

http://www.accutaneaction.com/adr/index.html

http://www.accutaneaction.com/adr/index.html#ranking

http://www.accutaneaction.com/adr/index.html#frequently

http://www.accutaneaction.com/adr/index.html#dechallenge

first link shows all.

Since it was approved by the FDA in 1982, its warning label has been changed more than 50 times because of adverse reactions. The list of side effects and warnings take up seven pages in the newly updated Physician’s Desk Reference. It’s among the top four drugs that attract the most reported adverse drug reactions on the FDA’s database. Due to the incidence of underreporting, the FDA estimates only about 1 to 10 percent of all side effects ever get reported to the agency. Based on this info, one can only imagine about how many serious side effects have occurred because of Accutane that have never been reported to anyone. Even Roche has admitted several years ago that there are over 40,000 Accutane adverse drug reaction reports on the database at their headquarters in Basel, Switzerland. As of today 266 cases of suicide have been reported to be caused by Accutane here in the United States, over 5000 psychiatric adverse drug reactions have been reported to the FDA and remember these probably represent only 1 to 10 percent of the actual number that have occurred. Since 1982, hundreds of deaths other than suicide (strokes, heart attacks, Crohn’s disease, and several other causes) have been recorded in the FDA’s adverse event reporting system. In the year 2007 alone, 430 cases of inflammatory bowel disease and 22 deaths were reported in connection with Accutane.

http://www.druglib.com/adverse-reactions_s...fects/accutane/

Accutane is only one of 3 drugs on the market that comes with a med guide, the other one is thalidomide, and I forget the 3rd.

I appreciate all the links, but I asked for a link to this FDA list you keep mentioning, not to accutaneaction.com.

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is birth control ranked as the top 4th dangerous drug on the market and only 1/100 side effects ever get reported? Don't think so :naughty:

Accutane's rank has no effect on whether or not it works.

Yes, but it clearly shows that you can't compare birth control to accutane

I clearly just did, as they clearly both have possible serious side effects and are clearly both being prescribed for non-life-threatening conditions.

the drug lib link above is from the fda, just for 2007

and one is clearly more dangerous than the other. birth control is not listed as top 4 on FDA's database, I am not a woman and do not have first hand knowledge of birth control, but I have researched Accutane so I can only suggest what I know. thank you for your time

I was looking on the FDA website and can't seem to find the list you're referring to. Could you please link me?

http://www.accutaneaction.com/adr/index.html

http://www.accutaneaction.com/adr/index.html#ranking

http://www.accutaneaction.com/adr/index.html#frequently

http://www.accutaneaction.com/adr/index.html#dechallenge

first link shows all.

Since it was approved by the FDA in 1982, its warning label has been changed more than 50 times because of adverse reactions. The list of side effects and warnings take up seven pages in the newly updated Physician's Desk Reference. It's among the top four drugs that attract the most reported adverse drug reactions on the FDA's database. Due to the incidence of underreporting, the FDA estimates only about 1 to 10 percent of all side effects ever get reported to the agency. Based on this info, one can only imagine about how many serious side effects have occurred because of Accutane that have never been reported to anyone. Even Roche has admitted several years ago that there are over 40,000 Accutane adverse drug reaction reports on the database at their headquarters in Basel, Switzerland. As of today 266 cases of suicide have been reported to be caused by Accutane here in the United States, over 5000 psychiatric adverse drug reactions have been reported to the FDA and remember these probably represent only 1 to 10 percent of the actual number that have occurred. Since 1982, hundreds of deaths other than suicide (strokes, heart attacks, Crohn's disease, and several other causes) have been recorded in the FDA's adverse event reporting system. In the year 2007 alone, 430 cases of inflammatory bowel disease and 22 deaths were reported in connection with Accutane.

http://www.druglib.com/adverse-reactions_s...fects/accutane/

Accutane is only one of 3 drugs on the market that comes with a med guide, the other one is thalidomide, and I forget the 3rd.

I appreciate all the links, but I asked for a link to this FDA list you keep mentioning, not to accutaneaction.com.

Call the fda by phone and ask them yourself, accutane reaction keeps all the fda's information and puts them together

o and the druglib is the fda's site just for 2007 though

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is birth control ranked as the top 4th dangerous drug on the market and only 1/100 side effects ever get reported? Don't think so :naughty:

Accutane's rank has no effect on whether or not it works.

Yes, but it clearly shows that you can't compare birth control to accutane

I clearly just did, as they clearly both have possible serious side effects and are clearly both being prescribed for non-life-threatening conditions.

the drug lib link above is from the fda, just for 2007

and one is clearly more dangerous than the other. birth control is not listed as top 4 on FDA's database, I am not a woman and do not have first hand knowledge of birth control, but I have researched Accutane so I can only suggest what I know. thank you for your time

I was looking on the FDA website and can't seem to find the list you're referring to. Could you please link me?

http://www.accutaneaction.com/adr/index.html

http://www.accutaneaction.com/adr/index.html#ranking

http://www.accutaneaction.com/adr/index.html#frequently

http://www.accutaneaction.com/adr/index.html#dechallenge

first link shows all.

Since it was approved by the FDA in 1982, its warning label has been changed more than 50 times because of adverse reactions. The list of side effects and warnings take up seven pages in the newly updated Physician's Desk Reference. It's among the top four drugs that attract the most reported adverse drug reactions on the FDA's database. Due to the incidence of underreporting, the FDA estimates only about 1 to 10 percent of all side effects ever get reported to the agency. Based on this info, one can only imagine about how many serious side effects have occurred because of Accutane that have never been reported to anyone. Even Roche has admitted several years ago that there are over 40,000 Accutane adverse drug reaction reports on the database at their headquarters in Basel, Switzerland. As of today 266 cases of suicide have been reported to be caused by Accutane here in the United States, over 5000 psychiatric adverse drug reactions have been reported to the FDA and remember these probably represent only 1 to 10 percent of the actual number that have occurred. Since 1982, hundreds of deaths other than suicide (strokes, heart attacks, Crohn's disease, and several other causes) have been recorded in the FDA's adverse event reporting system. In the year 2007 alone, 430 cases of inflammatory bowel disease and 22 deaths were reported in connection with Accutane.

http://www.druglib.com/adverse-reactions_s...fects/accutane/

Accutane is only one of 3 drugs on the market that comes with a med guide, the other one is thalidomide, and I forget the 3rd.

I appreciate all the links, but I asked for a link to this FDA list you keep mentioning, not to accutaneaction.com.

Call the fda by phone and ask them yourself, accutane reaction keeps all the fda's information and puts them together

o and the druglib is the fda's site just for 2007 though

Soooo you can't provide me with a direct link to the information you're throwing around?

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is birth control ranked as the top 4th dangerous drug on the market and only 1/100 side effects ever get reported? Don't think so :naughty:

Accutane's rank has no effect on whether or not it works.

Yes, but it clearly shows that you can't compare birth control to accutane

I clearly just did, as they clearly both have possible serious side effects and are clearly both being prescribed for non-life-threatening conditions.

the drug lib link above is from the fda, just for 2007

and one is clearly more dangerous than the other. birth control is not listed as top 4 on FDA's database, I am not a woman and do not have first hand knowledge of birth control, but I have researched Accutane so I can only suggest what I know. thank you for your time

I was looking on the FDA website and can't seem to find the list you're referring to. Could you please link me?

http://www.accutaneaction.com/adr/index.html

http://www.accutaneaction.com/adr/index.html#ranking

http://www.accutaneaction.com/adr/index.html#frequently

http://www.accutaneaction.com/adr/index.html#dechallenge

first link shows all.

Since it was approved by the FDA in 1982, its warning label has been changed more than 50 times because of adverse reactions. The list of side effects and warnings take up seven pages in the newly updated Physician's Desk Reference. It's among the top four drugs that attract the most reported adverse drug reactions on the FDA's database. Due to the incidence of underreporting, the FDA estimates only about 1 to 10 percent of all side effects ever get reported to the agency. Based on this info, one can only imagine about how many serious side effects have occurred because of Accutane that have never been reported to anyone. Even Roche has admitted several years ago that there are over 40,000 Accutane adverse drug reaction reports on the database at their headquarters in Basel, Switzerland. As of today 266 cases of suicide have been reported to be caused by Accutane here in the United States, over 5000 psychiatric adverse drug reactions have been reported to the FDA and remember these probably represent only 1 to 10 percent of the actual number that have occurred. Since 1982, hundreds of deaths other than suicide (strokes, heart attacks, Crohn's disease, and several other causes) have been recorded in the FDA's adverse event reporting system. In the year 2007 alone, 430 cases of inflammatory bowel disease and 22 deaths were reported in connection with Accutane.

http://www.druglib.com/adverse-reactions_s...fects/accutane/

Accutane is only one of 3 drugs on the market that comes with a med guide, the other one is thalidomide, and I forget the 3rd.

I appreciate all the links, but I asked for a link to this FDA list you keep mentioning, not to accutaneaction.com.

Call the fda by phone and ask them yourself, accutane reaction keeps all the fda's information and puts them together

o and the druglib is the fda's site just for 2007 though

Soooo you can't provide me with a direct link to the information you're throwing around?

Why you think im lying? Read through the websites

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I was looking on the FDA website and can't seem to find the list you're referring to. Could you please link me?

http://www.accutaneaction.com/adr/index.html

http://www.accutaneaction.com/adr/index.html#ranking

http://www.accutaneaction.com/adr/index.html#frequently

http://www.accutaneaction.com/adr/index.html#dechallenge

first link shows all.

Since it was approved by the FDA in 1982, its warning label has been changed more than 50 times because of adverse reactions. The list of side effects and warnings take up seven pages in the newly updated Physician's Desk Reference. It's among the top four drugs that attract the most reported adverse drug reactions on the FDA's database. Due to the incidence of underreporting, the FDA estimates only about 1 to 10 percent of all side effects ever get reported to the agency. Based on this info, one can only imagine about how many serious side effects have occurred because of Accutane that have never been reported to anyone. Even Roche has admitted several years ago that there are over 40,000 Accutane adverse drug reaction reports on the database at their headquarters in Basel, Switzerland. As of today 266 cases of suicide have been reported to be caused by Accutane here in the United States, over 5000 psychiatric adverse drug reactions have been reported to the FDA and remember these probably represent only 1 to 10 percent of the actual number that have occurred. Since 1982, hundreds of deaths other than suicide (strokes, heart attacks, Crohn's disease, and several other causes) have been recorded in the FDA's adverse event reporting system. In the year 2007 alone, 430 cases of inflammatory bowel disease and 22 deaths were reported in connection with Accutane.

http://www.druglib.com/adverse-reactions_s...fects/accutane/

Accutane is only one of 3 drugs on the market that comes with a med guide, the other one is thalidomide, and I forget the 3rd.

I appreciate all the links, but I asked for a link to this FDA list you keep mentioning, not to accutaneaction.com.

Call the fda by phone and ask them yourself, accutane reaction keeps all the fda's information and puts them together

o and the druglib is the fda's site just for 2007 though

Soooo you can't provide me with a direct link to the information you're throwing around?

Why you think im lying? Read through the websites

I never said you were lying. I just asked for you to link me to this FDA list. If you can't, you can't. *shrugs*

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My skin hasnt started to clear up yet. I have had bad skin for the past 3 years. During that time I have tried tetracycline, minocycline, doxycycline, clindamycin and all the suggested topical creams from dermatologist. Ive have been on AMNESTEEM(accutane) for 16 weeks now and all I noticed is extremly dry skin and lips and sensitivity to the sun. Im in the Coast Guard and I cant help but being out in the sun. So I get Sun burnt at least once a week evan thou I use face sunscreen. I eat healthy, drink lots of water and workout at least 4 times a week. Im trying not to give up hope for clear skin but im afraid that accutane wont work for me.

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What really bothers me about Accutane, is that I got mislead by the pharmaceutical company. Now I'm stuck here, trying to warn others of the severe dangers involved with taking Accutane.

All Roche had to do was put on the pamphlet

x. used in the treatment of brain cancer

or

x. slows down metabolism/cell division in the body/brain

or

x. permantley alters gene-expression

If I could have just been provided with full information, I would have stayed away from treatment.

I wouldn't be sitting here looking for growth factors to repair my brain, or the best anti depressant treatment to combat the Accutane induced brain-damage

They ruined my health in a unfair way

Right now the force that keeps Accutane on the market is money, not the health of the patients

I was aware of side-effects going into treatment, but nothing that would emerge months to years after. Something is definetly at fault, when a drug has side effects that do not appear until after you are done with it.

Most people will continue taking the drug, and some will end up suffering very badly, if only there was something I could do to prevent it from happening, but at the moment the economical influences are to strong

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My skin hasnt started to clear up yet. I have had bad skin for the past 3 years. During that time I have tried tetracycline, minocycline, doxycycline, clindamycin and all the suggested topical creams from dermatologist. Ive have been on AMNESTEEM(accutane) for 16 weeks now and all I noticed is extremly dry skin and lips and sensitivity to the sun. Im in the Coast Guard and I cant help but being out in the sun. So I get Sun burnt at least once a week evan thou I use face sunscreen. I eat healthy, drink lots of water and workout at least 4 times a week. Im trying not to give up hope for clear skin but im afraid that accutane wont work for me.

CLEARLY YOU HAVEN'T READ THE FIRST POST ABOUT RULES FOR POSTING IN THIS FORUM!

It's only for people who have FINISHED their courses of accutane and are suffering negative effects.

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jmiri gets all his "facts" from a site whose only purpose is to aid in lawsuits against roche and other producers of accutane. His claims of "millions" of sufferers of side-effects are backed by no credible sources, and he can't provide any links that shows unbiased and independent research on the subject.

oligirl said

I believe that yes, people should listen to thier doctors and what thier doctor suggest. However, with my experince I have learned to research outside of what my doctor has suggested.
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Thank you for this thread it was really needed. Hopefully now someone will be able to ask a question or state their experience that they had with accutane without it becoming an all out flame war. May I suggest that we also have another thread specifically for accutane studies because the posts become very repetitive.

That was our intent with this thread. :) One person whose thread was hijacked never returned to this site.

That's a good idea about the accutane studies thread.

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I have emailed the FDA to send a link to their top 10 list that is so frequently referred to here and other websites but that I have not been able to find on the FDA website.

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Those of you who think us anti-accutaners are simply overexagerating the effects of accutane should go and watch a documentry called the corporation. Basically i was watching it in one of my businesses classes, it is to do with corrupt businesses and how they cast a shadow over the real goings on within their companys.

They had a brief 2 minute segment showing the fines some businesses had incured due to wrong doings and corruptness. Guess who was top of the list and fined over 500million dollars in one year?

Hoffmann-La Roche.....

They are very good at pulling the wool over their potential customers eyes (evident by the response we often get from pro accutaners on here). So are all pharma companies but roche are by far the worst. OPEN YOUR EYES.

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I have emailed the FDA to send a link to their top 10 list that is so frequently referred to here and other websites but that I have not been able to find on the FDA website.

Jimiri- People aren't going to understand no matter how much you try to warn them unless the side effects happen to them. Some don't even believe what is printed in the medcine guide regarding side effects or published studies.

It seems it will always be a debate. One can only hope that the side effects don't happen to them. Hopefully things will change soon and doctors who prescribe this so easily and do not follow recommendations that are printed on the Roche Fda Online information, or thier prescriber guide, they will be penalized.

Wynne-thanks I would like to see that email from Roche. I wonder though does the list stay the same. I say that only cause I wonder how the list is comprised. Ex: Is it comprised of information they recive on adverse side effects of a drug? Is it comprised of the controversy of the drug? Is is comrpised of black box warnings of a drug.

I will say I did just go on the FDA website under accutane and there is a lot of information. Even transcripts of meetings held from 1983-2000 on Accutane. interesting.

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jmiri gets all his "facts" from a site whose only purpose is to aid in lawsuits against roche and other producers of accutane. His claims of "millions" of sufferers of side-effects are backed by no credible sources, and he can't provide any links that shows unbiased and independent research on the subject.

Is it proven that there is no connection? Are there any reliable studies that have found that there is no interaction with the brain from the drug?

Can such evidence be presented? No, because there is something to hide.

Are there any follow up studies?

No, the only thing that we know now is that with the most modern technology, significant changes in the brain are spotted when patients have been treated with Accutane, for the use of acne and brain cancer.

You would think after the bremner study there would be alot of interest in putting more money into research.

But nothing happens. Why ?

Read this link if you want to know what Roche tried to do after Bremner completed the brain studys...

http://www.beforeyoutakethatpill.com/index.php/tag/accutane/

"In other words, after wasting several million dollars and everyones time the basic conclusion that Accutane (isotretinoin) affects brain function was unchanged. The data even looked a little better than before on re-analysis.

Thanks guys! Look forward to working with you again!

I’ll leave you with a final quote from Hoffman La Roche Pharmaceuticals (in the context of why they charge $18,000 per year for an HIV drug in Korea where hardly anyone makes that much, total, in a single year, so they can’t afford the drug."

"We are not in the business of saving lives. We are in the business of making money. Our business is making money."

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Notice that a lot of posts that had been dumped are now back in full view for everyone. Those posts that had been dumped were separated from the original topics that had been derailed by the debate. The original topics are now back in Accutane posts and can have the original question answered. We are also able to preserve interesting debate here on this thread now. (some nine pages!!!!)

Please stop the accusations of favoritism by the moderators. That really pisses some of us off when we do try to be neutral as possible.

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jmiri gets all his "facts" from a site whose only purpose is to aid in lawsuits against roche and other producers of accutane. His claims of "millions" of sufferers of side-effects are backed by no credible sources, and he can't provide any links that shows unbiased and independent research on the subject.

oligirl said

I believe that yes, people should listen to thier doctors and what thier doctor suggest. However, with my experince I have learned to research outside of what my doctor has suggested.

funny. yesterday you were saying the complete opposite. that you should trust your dermatologist, that your husband (the DOCTOOOR as you keep reminding us) told you to trust him. that doctors know best. i told you you should research the treatments that are perscribed too you and today you are suddently mirroring my words exactly.

As for acne not being a deadly illness. Considering its effect on people's social life and the fact that it can be a major cause for depression makes it a serious condition. Something that requires treatment. Accutane is not a perfect solution, but for many its their last hope at clear skin. Blaming roche for side-effects from a drug you took WILLINGLY and on your own INITIATIVE is PATHETIC. Take some responsibility for your own health. Roche didn't give you acne, and they didn't force you to take accutane either.

I am soooo speechless at how some think..........I am really not even going to respond to any of this......really Ducks Three I don't remember every telling you not to take accutane. By the way I said that people should listen to thier doctor, but research what thier doctor is telling them. Not all doctors have patients best intrests.

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Mr. ducks....kindly remember that some people do indeed have side effects from Accutane. Blaming the victim is not at all polite.

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Mr. ducks....kindly remember that some people do indeed have side effects from Accutane. Blaming the victim is not at all polite.

Thak You Wynne.....

I wish everyone a good day, :D

I am acutally off to one of the many doctors I know have to see for my side effects.

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oli girl is not a victim (although she tries hard to make it seem like it). oli girl wasn't the "victim" of some freak accident. She wasn't the target of some gross injustice. Oli girl sought out a dermatologist for acne treatment, she was prescribed and purchased the accutane. she was or was not aware of the possible sideeffect (if she wasn't thats just ignorance on her part), and she took the pills hoping that it would cure her acne. When the side-effects hit she decides to blame roche....why?

I am aware that many have side-effects from accutane, still there are only a few that decide to file lawsuits against roche. A few that refuse to take responsibility for their own actions. The side-effects of accutane have been known for decades.

I acknowledge the side-effects of accutane. why is it that oli girl, jmiri and their likes REFUSE to acknowledge ANY of its benefits. With all the positive accutane diaries popping up on youtube, acne.org, reclaimyourskin.co.uk and similar sites, with people telling how accutane made a positive change in their lives, why is it that we should listen to a few bitter individuals who have no intention other then screaming "POISON POISON POISON!"

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oli girl is not a victim (although she tries hard to make it seem like it). oli girl wasn't the "victim" of some freak accident. She wasn't the target of some gross injustice. Oli girl sought out a dermatologist for acne treatment, she was prescribed and purchased the accutane. she was or was not aware of the possible sideeffect (if she wasn't thats just ignorance on her part), and she took the pills hoping that it would cure her acne. When the side-effects hit she decides to blame roche....why?

I am aware that many have side-effects from accutane, still there are only a few that decide to file lawsuits against roche. A few that refuse to take responsibility for their own actions. The side-effects of accutane have been known for decades.

I acknowledge the side-effects of accutane. why is it that oli girl, jmiri and their likes REFUSE to acknowledge ANY of its benefits. With all the positive accutane diaries popping up on youtube, acne.org, reclamyourskin.co.uk and similar sites, with people telling how accutane made a positive change in their lives, why is it that we should listen to a few bitter individuals who have no intention other then screaming "POISON POISON POISON!"

Only a few to decide to file lawsuits against ROche? Why is there a national class action lawsuit with thousands signed up then? If you go around on all those websites, there is also MANY negative experiences, so it goes both ways I guess.

But are the side effects so acceptable? Should a drug you take for your skin, be able to damage your brain, or have your colon removed, or make you crippled for life? and much much more

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