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I just want to let you know a little bit about my story with Spiro. First of all, I've taken minocycline, tetracycline, accutane, bactrim, and now spirolactone. This fun little process has been going on since I was 12 years old, and I'm now 23. Bactrim did well for the longest, from ages 16-22, but I hated taking the huge pill twice a day. I also developed IBS and wanted to get off of anything that might upset the bacteria in my intestines (since Bactrim is technically an antibiotic). About two months after getting off the Bactrim I broke out like CRAZY.

Finally fed up and ready to get back on birth control to see if that would help, I went to my OB/GYN, who also prescribed me Spiro for my face. I'd never heard of it before but thought it couldn't hurt. Taking Spiro along with my Ortho-Tri-Cyclen Lo birth control stopped any period irregularity. I am about the worst person in the world when it comes to drinking water, but I did just fine! I never had any problems with it, honestly.

I did have an initial breakout that lasted longer than most, the first 5 months are so. I'd say months 3-4 for the absolute worst. Then, like some sort of miracle, I cleared up the 5th month. Once it started, it happened fast. By the 6th month I was 98% clear, and today after being on Spiro for 8 months, I'm as clear as can be.

My acne was every kind you can think of: blackheads, whiteheads, cysts, etc. It was everywhere, and during the initial breakout from the Spiro about 2/3 of it was on my chin (a hormonal breakout spot). It was tough to stick through at the hard times, but after taking 100mg in the morning for this many months, I'm finally free from my acne with zero side effects. I drink soda, coffee, and milk mostly, and rarely drink up to a bottle of water a day. Needless to say, I'm doing just fine. Alot of people read things that aren't true and freak out about it, but if my body had a problem with my routine it would tell me about it, and I trust that.

Thought this might help, good luck in all of this!

- Tricia

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Congrats Tricia!

I am on my 4th month of Spiro and it just keeps getting better. I am on a low dosage of 50mg per day and I'm about 98% clear. I hope to stay on the low dose b/c I have a history of weird / bad reactions on longterm meds, mostly antibiotics. I developed toxic hepatitis on Bacrtim, Hives on Tetracycline, and Intestinal ulcers and bad IBS on Doxy. Needless to say AB's are no longer an option for me.

My GP told me Spiro is very safe despite the wacko claims you hear. He is also a heart specialist and told me in his 40+ years of practicing medicine he's never once heard of anyone having a bad reaction to spiro. He is happy I've finally found something that works for my acne (I'm 39 years old) and feels safe to let me stay on it longterm.

I just had my 3 month blood work done to check liver, bilirubin, potassium levels and all are A. okay. As long as this stuff stays in check, I plan to stay on spiro through menopause or however long the acne hormones last. I lost too many years of my life hiding away at home due to embarassing acne. Now thanks to spiro I don't have to.

I'm so glad it's working for you too. Only wish I went on it when I was 23, better late than never though!

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I wanted to wish you congrats as well!! I never got the horrible IB so that does suck but I'm sure you're glad you stuck it out. :)

I have been on Spiro for 3 months and like green eyes said, with each month comes better skin. I am 99% clear now. I got 2 small pimples from my period and those were the only two I've had in a while. My period is being kinda wacko right now, but I will live with that for the sake of clear skin. I am 100mg a day and will continue using this for as long as needed.

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The more I read about this, the more I want to start Spiro. I am going to see my derm next Monday, and I plan on asking her about this.

The only thing I fear is the IB, because I have a wedding in May that I want to look decent for. If my derm gives this to me, should I wait until after the wedding to start taking it? Do most people experience an IB the first few months of Spiro. I know one poster on this thread said she didn't, but the OP said she did and that it was "horrible" i'm really hoping that I don't have to wait 5 months before I get clear that's a long time! I guess it's worth it for clear skin right?

How much is the prescription with PPO insurance?

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I never got an IB on Spiro either. My skin was less oily after week one and either stayed about the same or improved consistently from there :)

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The more I read about this, the more I want to start Spiro. I am going to see my derm next Monday, and I plan on asking her about this.

The only thing I fear is the IB, because I have a wedding in May that I want to look decent for. If my derm gives this to me, should I wait until after the wedding to start taking it? Do most people experience an IB the first few months of Spiro. I know one poster on this thread said she didn't, but the OP said she did and that it was "horrible" i'm really hoping that I don't have to wait 5 months before I get clear that's a long time! I guess it's worth it for clear skin right?

How much is the prescription with PPO insurance?

Maybe you could take an antibiotic for a month or two (like April and May) just to make sure you'll be clear for the wedding. Also, my initial breakout lasted 28 days.

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Wow, reading your guy's posts gave me hope. I'm 23 and have persistant moderate acne. I have been on spiro for 2 months (after trying minocycline which didnt work at all) the spiro has done nothing for my skin yet.. but im keeping my fingers crossed. Sometimes I look in the mirror and cry cuz i feel like my acne will never go away, i guess i just have to keep trying though :)

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I'm on my seventh month of spiro and I'm finally clear. Things looked pretty hopeless for the first four months, then my derm added antibiotics and I haven't had a breakout at all in more than a month. My skin is still way too oily, but I'd rather be shiny than bumpy and red!

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I think the chance of getting an initial breakout is pretty slim, but it varies from person to person. When my doctor first prescribed Spiro to me he actually prescribed Doxy along with it to help with the IB, and I think that's pretty normal practice, just to be on the safe side. I decided not to take it just because I felt like I was taking a thousand other things, but it probably would have helped me. He said to take the Doxy just for a few months anyway.

I've heard alot of bad things about Spiro like it lowering your blood pressure, making potassium higher, making you need to pee, dehydrating you, etc. I swear I have had NO problems with it! Reading posts like that scared me, so don't take it too seriously! Spiro can really be a long-term solution for people like me. In my case the IB was terrible, but I'm so glad I stuck through those first four months because now it seems like nothing I can do will make me break out.

If you're concerned about it not working for you, give it 6 months to work before giving up. Please! My acne at it's worst would be considered moderate to severe. I didn't just have a couple, they were everywhere, deep, and painful. I really hope Spiro is as much as a miracle for everyone else as it was for me!

How much is the prescription with PPO insurance?
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Yeah, it seems more often than not ppl don't experience an IB...from what I have read anyway. You have a good chance of it not causing a huge breakout but of course that is not a certainty. I had a trip before I started Spiro and because of the possible IB I thought about delaying it. But...I was only prescribed 25mg for the first week and then was told to up to 50mg after that. I just decided to stay on the 25 mg until after my trip (3weeks I think) and then upped it. Like I said, I never got the IB so I would have been okay....but I thought better to be safe than sorry.I slowly upped myself from 25mg, to 50mg, to 75mg and now at 100mg for the past 6 weeks and been doing GREAT on it.

Good luck.

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