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Stem Cells for Acne Scar Repair (SCIENCE FACT, not science fiction!)

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Hi BRD are you able to respond to my query on page 32?

Hey Otis20,

I will respond in a few days as I'm too busy at the moment to give detailed responses in this thread. Come Sunday I will try to answer/respond to the posted questions/comments thus far in one shot. I hope that's ok with you.

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BRD BRD BRD

I am under the impression that when stem cells do there thing -they create the missing/damaged cell then they also re create another stem cell. Is that correct?

In a transferred fat graft what would keep the fat graft from not slowly growing into the

area from which it was taken?

I have had some kind of stem cell process happening to me, since I had a fat graft at the young age of 23 and now I am 39 only 5 pounds heavier. Yet I have had some very odd things happen

to the area that was grafted?? I would love to discuss with you.

The fat graft was taken from my inner knee, and I remember the doc said fat lasted longer from this area. Also he said he was leaving some blood attatched to the fat,to help it last.

Well 16 years later it lasted alright, but has been a very difficult journey for me.... I have been trying to reduce it.Please message me.

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BRD BRD BRD

I am under the impression that when stem cells do there thing -they create the missing/damaged cell then they also re create another stem cell. Is that correct?

In a transferred fat graft what would keep the fat graft from not slowly growing into the

area from which it was taken?

I have had some kind of stem cell process happening to me, since I had a fat graft at the young age of 23 and now I am 39 only 5 pounds heavier. Yet I have had some very odd things happen

to the area that was grafted?? I would love to discuss with you.

The fat graft was taken from my inner knee, and I remember the doc said fat lasted longer from this area. Also he said he was leaving some blood attatched to the fat,to help it last.

Well 16 years later it lasted alright, but has been a very difficult journey for me.... I have been trying to reduce it.Please message me.

Jaden, what kind of side effects have you had? I was actually just thinking about this--what is going to happen to the areas injected with stem cells as we age? Will those areas age more slowly and cause a strange appearance?

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BRD,

When was the last time you were in contact with the Aoluosi clinic? Have they discussed with you about how they are investigating using GF's from umbilical cords?

Hi FT,

I spoke to them more than a month ago. It was around the time that you had them contact me. They asked me about my methodology and I gave them a quick overview. They did not mention anything about isolating GFs from umbilical cords, but I can see the benefit of doing that to an extent. This is better than nothing, but perhaps another strategy would be to isolate GFs from a more potent source.

I have isolated GFs (identical to their human GF counterparts) from the embryos of 5 day old fertilized chicken eggs. These contain a host of beneficial GFs (ie: TGF-b3) that are not as abundant in later embryonic development. Human first trimester foetuses also have different GF ratios that allow them to generate/regenerate tissues with exceptional efficiency. As I've said before, foetuses at this stage of development can heal in a scarless fashion. At later stages this does change as various tissues in the body alter their responses to injury with inflammation that minimizes the risk of infection, but in also contributes to fibrous tissue growth at the expense of original tissue functionality.

How are you lately btw?

Best,

BRD

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BRD,

When was the last time you were in contact with the Aoluosi clinic? Have they discussed with you about how they are investigating using GF's from umbilical cords?

Hi FT,

I spoke to them more than a month ago. It was around the time that you had them contact me. They asked me about my methodology and I gave them a quick overview. They did not mention anything about isolating GFs from umbilical cords, but I can see the benefit of doing that to an extent. This is better than nothing, but perhaps another strategy would be to isolate GFs from a more potent source.

I have isolated GFs (identical to their human GF counterparts) from the embryos of 5 day old fertilized chicken eggs. These contain a host of beneficial GFs (ie: TGF-b3) that are not as abundant in later embryonic development. Human first trimester foetuses also have different GF ratios that allow them to generate/regenerate tissues with exceptional efficiency. As I've said before, foetuses at this stage of development can heal in a scarless fashion. At later stages this does change as various tissues in the body alter their responses to injury with inflammation that minimizes the risk of infection, but in also contributes to fibrous tissue growth at the expense of original tissue functionality.

How are you lately btw?

Best,

BRD

Hi BRD,

Did you speak with someone from Aoluosi or Ingela from the puhua hospital?

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So I've been looking up Stem Cells and it seems very promising. It can do many things that are just insane(in a good way). What's the wait for everyone not doing it? Because its only offered in other countries? And is this a 100% solution?

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This is the stem cell treatment by Tiantan Puhua. This is from a new correspondent who is in charged of acne scar apparently. When I receive the pictures from them, I will post them. Apparently most of their acne scar patients are referred to them by this korean hospital, https://rnl.co.kr/eng/main.asp. This looks pretty exciting but sadly I do not have the resources to go for this treatment as of now. Most likely I will need to wait at least 2 more years before I can afford this treatment. If anyone is interested in this I can forward the email to you :).

Im just curious to know whether BRD thinks this is legit and workable, as I have no medical training and this hospital, being from China, does not give me the greatest confidence. The treatment process and costs are outlined below.

P.S BRD, have you heard of RNL Bio before, its a company specialising in stem cell research, and refers patients to Tian Tan. I wonder if it is a reputable company.

Treatment Procedure:

The new plan will last 3weeks, 2 weeks for stem cell propagation and 1 week for injection. You do not need to stay in hospital after every procedure.

1) we will extract at the most 30ml fatty tissue from your abdomen under local anaesthesia.

2)The fatty tissue will immediately send to lab to isolated and cultured. that will forming new blood vessels, collagen fiber and regennerating tissues.

3) After two weeks, you'll receive two times stem cell injection (with in one week)of your autologous adipose stem cell. For some oversea patients, they don't want to travel again after 6 months for 2nd time injection, so we make the other short term plan for them. because you are not in China, so I recommend the 3 weeks plan to you. If travel again after 6 months will not be a problem, you can have the 2nd injection after 6 month.

Before every injection,you will receive stem cell growth factor injection at the same day. Each time you'll receive 50 millions stem cells.We inject the cell mix with growth-promoting media and use 1ml syringe (every time you will receive 4 syringes) with very thin needle for stem cells injection and roller with needle for stem cell growing factor.

Cost:

The total treatment fee is 58,000RMB (about 8,660USD) which is including 10 years stem cells storage, liposuction, 2 times injection and stem cell growth factor injection. after then, 10,000RMB injection each time.

Concerning before and after photos, most of our patients are send by our Koran cooperative partner( Kora RNL), https://rnl.co.kr/eng/pr/pr_news_read.asp. they keep all the photos and we'll send to you once we get them.

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hiya, I e.mailed the Tiantan Puhua hospital the other day and they replied saying they could,nt help as they don,t do treatments for scarring! Do u think i,ve e.mailed the wrong hospital?

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This is great news Vanzzzz. Thank you.

The only thing "strange" is that they will perform the second injection in the same week, when it seems like they rather would wait 6 months.

Great if you can post those pictures when you get them !!!

Thanks again.

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This is the stem cell treatment by Tiantan Puhua. This is from a new correspondent who is in charged of acne scar apparently. When I receive the pictures from them, I will post them. Apparently most of their acne scar patients are referred to them by this korean hospital, https://rnl.co.kr/eng/main.asp. This looks pretty exciting but sadly I do not have the resources to go for this treatment as of now. Most likely I will need to wait at least 2 more years before I can afford this treatment. If anyone is interested in this I can forward the email to you :).

Im just curious to know whether BRD thinks this is legit and workable, as I have no medical training and this hospital, being from China, does not give me the greatest confidence. The treatment process and costs are outlined below.

P.S BRD, have you heard of RNL Bio before, its a company specialising in stem cell research, and refers patients to Tian Tan. I wonder if it is a reputable company.

Treatment Procedure:

The new plan will last 3weeks, 2 weeks for stem cell propagation and 1 week for injection. You do not need to stay in hospital after every procedure.

1) we will extract at the most 30ml fatty tissue from your abdomen under local anaesthesia.

2)The fatty tissue will immediately send to lab to isolated and cultured. that will forming new blood vessels, collagen fiber and regennerating tissues.

3) After two weeks, you'll receive two times stem cell injection (with in one week)of your autologous adipose stem cell. For some oversea patients, they don't want to travel again after 6 months for 2nd time injection, so we make the other short term plan for them. because you are not in China, so I recommend the 3 weeks plan to you. If travel again after 6 months will not be a problem, you can have the 2nd injection after 6 month.

Before every injection,you will receive stem cell growth factor injection at the same day. Each time you'll receive 50 millions stem cells.We inject the cell mix with growth-promoting media and use 1ml syringe (every time you will receive 4 syringes) with very thin needle for stem cells injection and roller with needle for stem cell growing factor.

Cost:

The total treatment fee is 58,000RMB (about 8,660USD) which is including 10 years stem cells storage, liposuction, 2 times injection and stem cell growth factor injection. after then, 10,000RMB injection each time.

Concerning before and after photos, most of our patients are send by our Koran cooperative partner( Kora RNL), https://rnl.co.kr/eng/pr/pr_news_read.asp. they keep all the photos and we'll send to you once we get them.

This sounds very promising and the only thing is the price :/, cause then you have to pay to get there and where to stay and eat in that country. Hopefully we can have something similar in the US. But here in the US not too many derms care about acne scarring as it doesnt happen to many of us.

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Regarding the treatment, the only thing i am concerned about is the growth factor. According to my doctor, the stem cells are created using enzymes to break down the fat. Afterward, either bacteria or animal stuff is used as growth factor to multiply the stem cells.

The problem with using these foreign reagents is that there may be a chance of complication occurring if the lab is not careful..

I am not familiar with the process but this was what my doctor told me. Thus it is better to do this treatment in a reputable hospital in order to minimize complication. Kinda like how you want an experienced derm to so the surgeries on your scars, cept in this case it is experienced and reputable hospital. In fact, my doctor mentioned how he saw very good results from japanese hospitals.

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Well, I haven't heard from the Belgian research center yet and to be honest I don't think I will. Also, when I had them on the phone a while ago they were actually quite rude so I'm not excited about calling them.

I'll see what else I can do to find a list with places that offer treatments, ok?

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If you want try calling them yourself you can, though. Here's their number:

+ 32 16 33 02 95

Ask for Erik Bogaerts, the co-worker of Catherine Verfaillie.

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Hi guys,

I am very busy the last few days and thus haven't answered your questions. Since I don't want to leave anyone out I will spend a few hours replying to everyone when I get the time to do so. I also want to commend all of you that are researching stem cell therapies and contacting various clinics, doctors and scientists. You know who you are. We're going to make this work one way or another even if some people here seem to disagree with a synergistic top-down and bottom-up approach. You do your part and I'll do mine.

:)

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Great.

@icaretohelp

What's the exact treatment you got from Dr.Khan ? Great that you will be satisfied. :)

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I did STEM cells and PRP injections with dermarolling

I thought you didnt really do the "stem cell"?Could you explain the treatment a bit more.

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Hi guys,

I am very busy the last few days and thus haven't answered your questions. Since I don't want to leave anyone out I will spend a few hours replying to everyone when I get the time to do so. I also want to commend all of you that are researching stem cell therapies and contacting various clinics, doctors and scientists. You know who you are. We're going to make this work one way or another even if some people here seem to disagree with a synergistic top-down and bottom-up approach. You do your part and I'll do mine.

:)

Hey BRD, I have two questions as well. As you can tell from my username I don't have acne scars. Instead I have a solitary, depressed scar due to an injury which I sustained during a near fatal traffic accident. I fell on the ground at high speed. I'm still very handsome, though. lol :) But needless to say, if the scar can be improved it would be cool. It already has improved a great deal through a few Vbeam treatments (and I plan on getting a few more) but if stem cells could eventually take it even further that would be interesting.

Do you think I could benefit from stem cell injections the same way as people with acne scars possibly can? Or should I expect different results, hypothetically?

Also, I noticed you mentioning the chicken eggs... I can see a vegan or a vegetarian being reluctant to get treated because of that. So I was wondering, do many potential stem cell treatments make use of things that are derived from animal products?

Thanks.

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Hi guys,

I am very busy the last few days and thus haven't answered your questions. Since I don't want to leave anyone out I will spend a few hours replying to everyone when I get the time to do so. I also want to commend all of you that are researching stem cell therapies and contacting various clinics, doctors and scientists. You know who you are. We're going to make this work one way or another even if some people here seem to disagree with a synergistic top-down and bottom-up approach. You do your part and I'll do mine.

:)

i also have a question but its not about scars or stem cells. it is to do with a skin problem that i have had for a while and doesnt seem to go away. its hard to explain properly but i can post a picture of my skin. should i post it here as you inbox is full (its not about scars though) ?

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I just want to quickly post an article (courtesy of sciencedaily.com) summarising an exciting development in regenerative medicine. As I've said, things are moving fast and before we know it our wildest abstract fantasies of regenerative medicine may come to blossom in the seemingly concrete reality that we inhabit.

Experts grow new teeth in adult mice

--------------------------------------------------------------------------------

Aug. 3, 2009 (Reuters) — Scientists in Japan have managed to grow fully functional teeth in adult mice using cells from an embryo, and they hope the same technology can be used to grow human organs in the future.

The researchers described how they had developed a "bioengineered tooth germ" - or seed containing certain cells taken from a mouse embryo. The seeds were later transplanted into the jawbones of adult mice.

"The hardness of the enamel and dentin of the bioengineered tooth was equivalent to those of a natural adult tooth," they wrote in response to questions from the media.

The new tooth also came complete with nerve fibers and the mice responded to pain tests.

Led by Takashi Tsuji of the Research Institute of Science and Technology at the Tokyo University of Science, the team hopes this technology can be used to grow human organs.

"The ultimate goal of regenerative therapy is to develop fully functioning bioengineered organs that can replace lost or damaged organs following disease, injury or aging," they wrote.

(Reporting by Tan Ee Lyn; Editing by Sanjeev Miglani)

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Hi BRD,

If the skin is dermabraded where hair currently exists and then stem cells are injected into this area followed by an application of GFs & ACell, would the hair regenerate along with healthy tissue or is there a good chance the hair does not return? thx

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