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Sydnor

Generic Accutane (Sotret) Log for Moderate Acne

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DAY TWO (1st entry)

Subject: 22 year-old Caucasian male, approx. 5'4" & 118 lbs. (I look much younger.)

Affliction: Moderate Acne vulgaris, especially blackheads and pustules, with episodic nodules and cysts (painful). I have been dealing with acne since I was about 13 years old. Neither of my parents had it as bad as I do, and I don't have it as bad as my brother.

Prior treatments: Several antibiotics, Topicals and Treatment Regimens. Prescription and OTC. Did try Proactiv, which demonstrated some temporary success. No surgical or laser procedures.

* Typical results consisted of a honeymoon period of success, followed by increased resistance to the treatment. Controlled rotation of products as a possible solution to resistance failed.

* A week prior to starting the Isotretinoin, I had been on Doxycycline 100 mg, b.i.d. for 5 days, which showed some improvement.

Current prescription: Sotret, 20 mg, b.i.d. (40 mg per day, total)

Ritual: Taken w/ food, copious amounts of water. I swallow the capsule just prior to beginning my breakfast or dinner meal.

Cleansing Regimen:

- Disposable exfoliating cloth, 2-3 times per-day, rough side first, then the smooth side.

- Neutrogena Advanced Solutions glycolic facial peel once per-day, at night (following use of exfoliating cloth).

- Throughout the day, rinse with water, as needed. Sometimes use Neutrogena Oil-Free Acne Stress Control Power Foam wash (it's really rather mild, lol).

- ChapStick Botanical Medley (the one w/ coconut and beeswax), as needed.

PLEDGE: Absolute teetotaling of alcohol consumption. I am committed to minimizing the burden placed on my liver and avoiding any negative interactive effects between the medication and alcoholic products. I have read a few horror stories which motivate me to stick to my pledge.

***

Okay, so I am starting this log after having officially been on Sotret (Generic Accutane) for approximately one day. I have taken 3 capsules so far, equating to 60 mg of Sotret. It is too bad that I did not take any pictures before starting, because I would argue that along with an immediate development of minor side effects, I have also seen some improvement.

Yes, in 24 hours I got:

(mild) SIDE EFFECTS, including

- Chapping of the lips

- Arthritic symptoms in hand and back

- Dehydration

- Slight heaviness, pain in head; reminds me of mild sinus issues.

- Gas, Stomach Upset*

* NOTE - I have had a previously diagnosed condition of Irritable Bowel Syndrome. Thus, stomach complications are not a surprised additional side effect for me.

Improvement:

- Reduction in oily complexion of face

- Reduction in size of cystic and pustular acne

Day Two Pictures are attached.

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hey man! im on my day 3! so we started almost the same! Im on sotret as well but on one per day 30mg! I wonder what is the difference between the generic and the brand. Less side effects? Someone please chime in on this!

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Um, my derm really wanted me on the Brand Name and referred to most generics as "garbage." She would have preferred Amnesteen over the other generics, saying that it produces more modest, but comparable results.

But I have Tricare Prime insurance as a military dependent (for exactly 6 more months, LOL... just enough time to finish the regimen), so I am stuck with either Claravis or Sotret generics without preauthorization. Basically, I have to prove that the generic doesn't work for me before I can use the brand name. Thus, I'm going to see what happens with this drug in a month.

As I understand it, the generics usually produce fewer and less severe side effects, even though the active ingredient is essentially the same. Personally, if the generic brand works a little slower, but still works, is cheaper, and the side effects are less dramatic, I'm all for the generic.

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I am currently experiencing a headache that feels like a permanent hangover. I've also experienced the dry eyes and this warm discomfort in my ears like an infection.

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Day 3

Waking up in the middle of the night to use the bathroom. But that's no surprise considering how much water I'm drinking. The headache has almost disappeared.

Status: Skin became oily at some point. Continued to see a reduction in size of cystic and pustular acne, but an increase in redness.

Mood: Optimistic :)

I might try to play soccer or run a track meet tonight, or salsa with some beautiful ladies if I'm lucky. Lol. I'll let ya'll know how any or all of that goes.

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Day 4

Progress:

Good

- So far, I have noticed an overall reduction in the oily complexion of my skin.

- I have seen a complete elimination of pustular acne, and a reduction in the size of all cystic acne.

- In the past 12-18 hours I have seen reduced redness of acne spots.

Bad

- Acne spots have cropped up in places I don't normally have problems - notably, my forehead.

> This may be due to the temporary increase of oil I observed yesterday.

Side Effects:

- The big headache went away, but sometimes I still feel "hungover."

> I always feel thirsty/dehydrated, which adds to my perceived fatigue.

- Mild dryness of my lips, hands and knees requires chapstick and lotion.

- I have continued to observe slight pain in my joints and back.

Additional Notes:

Good news! I did run in an intramural track meet last night, which I didn't train for at all, lol. I did feel abnormally drained after my brief warm-up for the race, especially dehydrated, and my muscles were more tense after stretching than they should have been, even if I haven't been training. However, I was able to sustain a five-minute mile pace for 2 laps, and ended up finishing the mile in 5:32. I'd say my failure to complete a five-minute mile was mostly due to lack of training, even if the medication made it more difficult (boy did my body lock up on the final lap... my back felt very stiff, which is something I've never experienced before. My friend from work caught up to me from 75m behind and ended up beating me by 100m).

Overall, I seem to be lucky. ::Knock on wood::

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Day 5

Just a quick update:

Each day seems to be a part of a cyclical process where it gets a little bit better overall, even though it sounds worse in some way. Today I see a couple of puss-filled lesions on my chin that are smaller than what I'm accustomed to seeing. The rest of the acne lesions which became red marks are starting to fade, and I can see zones in my face that are becoming absolutely clear and healthy-looking.

Most of the side effects have become so mild that they aren't mentionable, or they have actually disappeared. I do have sort of a stiff back and neck, and sometimes I feel a quick burst of pain in one of my joints. I also have to keep applying Chapstik all day. Other than that, so far, so good.

By the way, I take my pictures like right after I wake up, so in general, I look a bit unkempt. My apologies, lol.

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Um, my derm really wanted me on the Brand Name and referred to most generics as "garbage." She would have preferred Amnesteen over the other generics, saying that it produces more modest, but comparable results.

But I have Tricare Prime insurance as a military dependent (for exactly 6 more months, LOL... just enough time to finish the regimen), so I am stuck with either Claravis or Sotret generics without preauthorization. Basically, I have to prove that the generic doesn't work for me before I can use the brand name. Thus, I'm going to see what happens with this drug in a month.

As I understand it, the generics usually produce fewer and less severe side effects, even though the active ingredient is essentially the same. Personally, if the generic brand works a little slower, but still works, is cheaper, and the side effects are less dramatic, I'm all for the generic.

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Day 6

Same-old, Same-old. Lips are getting dryer, stuff is in a bit of a fluctuation. I get a little oily every now and then. Still optimistic.

:pray:

I am going to start deleting pics from prior posts because I can only use so much space on this blog. Rest assured that I am still taking them, though. If you want to see pics I have deleted, just let me know.

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Day 7

Almost one week down, and my face is already looking MUCH better. I am a lucky one. With the exception of dryness ... all over my body... and thirst, the side effects have generally subsided. Hopefully I don't see one of those "initial breakouts" I've read about... ::knock on wood::

Progress:

- Continued reduction in the swelling of cystic acne, no visible pustular acne.

- Mainly "spots" where acne swellings used to be.

- Redness has become fainter, more of a pink.

- Nicer complexion.

My mother commented today that my face is "looking better and better every day." :dance:

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Day 8

Still lookin' better than before. Too busy to say much more than that, other than I had a bout of dry eyes today that sucked.

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