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Mr Pipps

Mr Pipps' (UK) daily accutane log

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Background

Twenty five years old. Persistent, mild, resistent acne since age nine.

I am a classic Type 1 - very pale skin and green eyes. Every spot and blemish effects my skin with powerful illumination.

After years of excessive Benzoyl Peroxide and emasculating daily makeup, I finally broke. A visit to my city's finest dermatologist, who just happens to be my new Doctor, and I have four weeks signed off work and a prescription for accutane.

Day One

Four weeks later, I necked my first pill there and then in front of the pharmacist. And I couldn't help but smile - I had waited sixteen years for that moment.

I am back in the office on Monday and with clients on Tuesday. So as you can imagine, it's still thick Panoxyl (Benzoyl Peroxide) twice every day.

Starting on 20mg per day for first two weeks. Increasing to 40mg per day thereafter.

It begins now!

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Good luck on ya treatment :D!

I'd take it ez on the BP while on accutane! Might not hurt for the first few days but when your skin dries up and becomes more fragile/ sensitive, I would discontinue use. BP is a harsh product, as is accutane so mixing them together might lead to excess irritation and added redness... It might make things look a lot worse! I am not a doctor to be talking though, but just telling ya what I've heard and came up with! Try it and let us know :D...

Keep us posted! :)

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Day 2

Took my 20mg with a bowl of muesli and milk. I hope there was enough fat in the semi-skimmed milk.

Malvolent, thanks for the advice. :)

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Day 3

My third Isotretinoin pill.

I have begun taking fish oil. Super concentrated 1000mg fish oil, from Holland & Barrat. It contains:

EPA 300mg

DHA 300mg

I plan to take three fish oil tablets a day.

From my research, it would appear that this supplement is essential to any successful accutane regime.

I am continuing with the twice daily BP. No problems or particular dryness, yet.

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Guest AcneProne_1977
Day 3

My third Isotretinoin pill.

I have begun taking fish oil. Super concentrated 1000mg fish oil, from Holland & Barrat. It contains:

EPA 300mg

DHA 300mg

I plan to take three fish oil tablets a day.

From my research, it would appear that this supplement is essential to any successful accutane regime.

I am continuing with the twice daily BP. No problems or particular dryness, yet.

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Day 4 and day 5

My lips are starting to feel a little cracked and dry in the very corners of my mouth.

Also, despite plentiful amounts of Eucerin to regulate the BP, my skin appears to be more flakey than usual when on the regime.

I have reduced the BP to one application per day, in the evening.

Robyn, thanks for the encouragement! Good to hear you're on the fish oil too. My dermatologist's strategy with commencing on a 20mg daily dose was that it will most likely avoid and initial breakout within the first month.

I hope he is right.

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Guest AcneProne_1977
Day 4 and day 5

My lips are starting to feel a little cracked and dry in the very corners of my mouth.

Also, despite plentiful amounts of Eucerin to regulate the BP, my skin appears to be more flakey than usual when on the regime.

I have reduced the BP to one application per day, in the evening.

Robyn, thanks for the encouragement! Good to hear you're on the fish oil too. My dermatologist's strategy with commencing on a 20mg daily dose was that it will most likely avoid and initial breakout within the first month.

I hope he is right.

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Day 6 and day 7

I've begun taking my pill with lunch instead of dinner. I figure that there is more fat content in a larger lunch meal. What do you think?

Robyn, thanks for the recommendation. I've been using an E45 lip balm so far. I will definitely look out for Aquaphor.

I have not noticed any notable improvement in my skin as yet.

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Day 8

My lips are beocming slightly drier. So is my face. No problem though. It's hardly noticeable. In fact, I quite like the dry feeling.

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Hey good luck, I just wanted to say I don't think it's a good idea to use BP at the same time as Accutane....Tane may or may not dry your face out (depending on your dosage), but nonetheless Accutane is all you need to get clear skin. BP might possibly just irritate your face more, and could even make your skin redder. Plus, as Malevolent mentioned, your skin is much much thinner while on Tane. Just curious, why do you want to be on both at the same time? For most it's recommended that you just use a gentle wash and moisturize a lot while on Accutane.

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hi Mr Pipps.. i'm 2 days ahead of u.. and on 20 mg. as well..and yeah.. dry lip.. almost everyone on Tane experience it..lolz.. so well..just get a lip balm.. and apply on ur lip when u feel that it's cracking a lot..else when u try to brush the skin off.. it may cause ur lip to bleed a little.. so just be careful.. gd luck :P

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Day 9

I recently found this article very encouraging and informative.

Low-Dose Isotretinoin for Acne Vulgaris - Adverse effects are dose-related, so lower-dose isotretinoin is an exciting prospect.

...95% of patients achieved considerable improvement or complete remission of their acne.

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yep! roaccutane has proved very very effective! After finishing the course you will find your acne will still improve. It has high remission rates due to the shrinkage of the sebaceous glands.

Also Im glad you decided to stop the panoxyl!

Products like that are advised against whilst on roaccutane as they are " keratolytic " i.e.strip the top layer of skin really.

Whilst you are on roaccutane the skin will be more fragile due to the drugs mechanism of action and will be prone to shedding, using benzoyl peroxide in the various strengths may only aggravate redness and cause irritation!

Im on 40mg OD, halfway through my third week. Currently have quite a bit of redness but the eucerin and an anti redness cream i purchased tend to calm it. Also my lips are going! but nothing a bit of blistex can't solve. If you get a chance read through my diary, as my symptoms are very similar to yours! dose as well!

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Days 12 and 13

I think I am beginning to experience adverse side effects. In other words, an initial breakout!

Over the last 2-3 days I have noticed that a number of unusually large pimples have been present on my face first thing in the morning. What has been even more difficult, is that on promptly dealing with the offending follicle infections, I have discovered the hard way that my skin is indeed a lot softer and more easily breakable that it has been historically. Dealing with a spot has therefore caused far more skin breakage and redness than I would’ve usually expected. I have concluded that dealing with a pimple whilst on Accutane is almost a recipe for disaster. In fact, it’s effectively a loose-loose situation.

So I have started back on the Panoxyl 2.5% benzyl peroxide. I have applied it only to my chin, in the hope that I will not experience any further breakouts in that area. It is interesting to note that the breakout has only been on my chin and nowhere else. The spots on my back have remained exactly the same. Cheeks and forehead have certainly improved since commencing Accutane.

The thing that bother me is that an initial breakout isn’t supposed to happen when taking only 20mg. But who knows, perhaps my breakout would’ve been much worse if I’d started on 40mg.

I am due to increase to 40mg on day 15. That is when the real ‘fun’ should begin! lol

Blackhole, thanks for your advice and support. I am definitely also finding the Eucerin to be really helpful. Out of interest, where are you from the in the UK?

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Guest AcneProne_1977

Sorry to hear about your breakout, but, it sounds like Accutane is doing it's "thing"!

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Day 14 - two weeks in.

I double my dose tomorrow - 20mg to 40mg. I look forward to it!

The initial breakout, isolated solely to my chin for reasons entirely unknown, has caused significant skin breakage. I am finding that my skin is taking significantly longer to heal. What a bain.

I must stress, that cheeks and forehead have been clear since commencing accutance. My neck, which has always been a terribly problem area, has also seen improvement.

A glimpse of hope, two weeks in. Maybe, one day not so far from now, I will look like a normal human being... :)

Roll on day 15!

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I'm with Juls, on this one - I think you should totally ditch the BP and let the 'tane go about its business. Some of the spots you're currently brewing might go away of their own accord due to the action of the 'tane working from beneath them - if you put BP on top of them and thin-out the epidermis even further, you might interfere with that process and make the spots more prominent and potentially scarring than they would otherwise be.

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Guest AcneProne_1977
I'm with Juls, on this one - I think you should totally ditch the BP and let the 'tane go about its business. Some of the spots you're currently brewing might go away of their own accord due to the action of the 'tane working from beneath them - if you put BP on top of them and thin-out the epidermis even further, you might interfere with that process and make the spots more prominent and potentially scarring than they would otherwise be.
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Day 15 - two isotretinoin tablets today. One with breakfast and one with dinner.

I do wonder whether the fact that I eat absolutely not fat from day to day may be effecting how much isotretinoin is being absorbed into my system. Oh well...!

DH, Robyn, I think you're both right. I am now quite the BP. My skin is taking much longer to heal now and I don't want to do anything to slow the process down any further.

I'm looking forward to seeing what effect the 40mg has on my skin!

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Days 16 and 17

No noticeable increase in dryness yet.

Would anyone please advice as to whether I should be trying to eat more fat than normal? How important really is fat for the proper absorption of Isotretinoin?

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How to make skin heal more quickly, when on Accutane?

I find that my skin breaks very easily now that I've been on 40mg for two weeks.

For instance, I had a cold recently. It required regularly wiping of my nose with a handkerchief. Now my septum is sore and bleeds whenever I wipe my nose. The skin-healing process I had taken for granted all my life so far, is barely happening any more.

Surely something can be done to correct this momentary lapse in epidermical regeneration?

PS: Due to recent 15 hour days at the office, days 18 to 27 have flown by!

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Rhys - the regeneration of your epidermis is not lapsing, at all. It's occurring much, much more quickly. The cells are being replaced at several times the usual rate and, in the process, your epidermis is thinning-out, making your skin more fragile and slower to heal.

Other than keeping the skin properly moisturised, eating and drinking properly, and getting enough sleep, I don't think there's much more that you can do. Other than stop taking the pills...

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Guest AcneProne_1977

I usually eat a low (or no) fat diet as well, but I started eating a spoonful of peanut butter just before taking my pill everyday because, apparently, it's WAY better absorbed with fat. Do you like PB??

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