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is my skin getting too used to my creams?

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hey! alright.. so i've been on this 3 topical creams:vitamin A,fucidic acid(antibiotic cream), and enrythromycin lotion. it has been working good but i've been on them since june 3rd, so it's been almost 5 months. i feel like i can put as much on as i want to and will have no side effects at all. do you think that since i've been on it for so long my skin will start not reacting to it at all? do you think i should get a higher percentage of my creams?

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