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Benzoyl Peroxide Cautions: Benzoyl peroxide (BP) generates free radicals in the skin. Its effect is similar to unprotected sun exposure. The redness of the skin (erythema) caused by the sun and BP is the result of free radicals (oxidative stress) upon the skin. Repeated sun exposure and BP use generates free radicals that damage the skin's structure and cellular DNA, resulting in premature aging of the skin. The extent of the damage and aging from BP is determined by the concentration of BP, the frequency of applications and the duration of its use. Non-medical skin professionals should no knowingly damage skin or promote its premature aging.

Because benzoyl peroxide generates free radicals it interferes with and slows the healing process. The red and brown marks that are a part of the acne healing process may last weeks longer when BP is a regular part of the daily regimen.

Benzoyl peroxide has been linked to cancer for a number of hears and many research journal entries state "benzoyl peroxide is a free radical-generating skin tumor promoting agent." Performing a word search of the words "benzoyl peroxide cancer" in PubMed in the National Library of Medicine produces 102 articles from medical publications dealing with research aspects of BP and cancer. About two-thirds of the research supports linkage between BP and cancer.

Skin care professionals are reminded, "In 1995 the FDA changed benzoyl peroxide from a Category I (safe) to a Category III (safety is uncertain) ingredient and stated this action (56 FR 37622) was based on new information that raised a safety concern regarding benzoyl peroxide as a tumor promoter in mice..." Additionally, the FDA charged manufacturers with the responsibility of providing this information to consumers so they could make educated decisions. A more complete FDA statement is at the bottom of this page for your reference.

Use of BP to control or maintain the control of acne may promote severe skin damage. Aestheticians selling benzoyl peroxide products should advise the client of the potential of premature skin aging, skin cancer or the potential of developing benzoyl peroxide-induced eczema from BP contact dermatitis. BiON has given particular attention to providing effective treatment with no side effects and does not use benzoyl peroxide.

FDA / Benzoyl Peroxide Action: February 17, 1995

Food and Drug Administration / Department of Health and Human Services: "Topical Drug Products Containing Benzoyl Peroxide: Required Labeling"

"The Food and Drug Administration (FDA) is proposing additional labeling (warnings and directions) for all topically-applied acne treatment products containing benzoyl peroxide. The warning advises consumers to avoid unnecessary sun exposure and to use a sunscreen when using a benzoyl peroxide product to treat acne..."

"The agency classified benzoyl peroxide from its previous status Category I to Category III status. This action (56 FR 37622) was based on new information that raised a safety concern regarding benzoyl peroxide as a tumor promoter in mice and a study that reported that benzoyl peroxide has tumor initiation potential."

"FDA evaluated these data and information and determined that the studies show that benzoyl peroxide is a skin tumor promoter in more than one strain of mice as well as in hamsters. To date, topical studies (which have shown only tumor promotion) have been of short duration (about 52 weeks). Although animal data and human epidemiology data are available, the agency has determined that further studies are necessary to adequately assess the tumorigenic potential of benzoyl peroxide. These studies are currently being conducted. The agency acknowledges that it may take several years for these studies to be completed and analyzed, and for a final determination to be made on benzoyl peroxide's safety."

The use of benzoyl peroxide products generates free radicals in the skin and interferes with and slows the healing process. The red and brown marks that are a part of the acne healing process may last weeks longer when benzoyl peroxide is a regular part of the daily regimen. Benzoyl peroxide may increase the risks of acne scarring.

And now my face is like a hyperpigmentation factory

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Guest papillon

Yup. My red marks turned redder with the use of BP. Sad for me. Now, it's going to take a long time to get rid of them. BP sucks in my opinion. =O(

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yeah, i kinda noticed this as well. i'm going to try to stop using the stuff because i just keep hearing bad stuff about it.

now i'm trying to find things that help with the hyperpigmentation and focusing on actually having HEALTHY skin...not just punishing my skin for having acne. the breakouts i get aren't all that bad anymore (i think nature's cure is helping), if i could just get rid of these darn red marks i think my face would look soooo much better.

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I get HP scarring quite badly because i'm mixed race. CP serum is the only thing I have found that helps.

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