Aknemycin Plus : Erythromycin (4%) and Tretinoin (.025%) Solution

Brand:
Reviews
3.1
24 Reviews

Active Ingredients: Erythromycin (4%) and Tretinoin (.025%). Inactive Ingredients: Mineral oil, petrolatum, paraffin, talc, titanium dioxide, trilaureth 4 phosphate, oleyl oleate, tricetareth 4 phosphate, cetostearyl alcohol and sorbitol.

Items marked with red have tested a 3 or above (out of 5) in comedogenic (pore-clogging) testing.

The list of ingredients above is provided for informational purposes only. Always check the actual product label in your possession for the most accurate ingredient information due to product changes or upgrades that may not yet be reflected on our web site.

5
4%
4
32%
3
36%
2
20%
1
8%

Used Aknemycin Plus : Erythromycin (4%) and Tretinoin (.025%) Solution? Rate It:

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December 21, 2023
Did not work for me, acne became worse
I used Aknemycin plus for 6 weeks after I developed a painful and inflamed acne on my jawline, cheeks, around mouth and chin, which my usual go for Dual gel (benzoyl peroxide and clindamycin) would not touch. I am 35 years old female and struggled with acne since 12 years old but never experience so aggressive acne as now. My dermatologist prescribed Acnemycin plus once a day (at night) and Skinoren cream in the morning. I did separate review for Skinoren cream - but in nutshell neither worked for me and my acne got massively worse and much more inflamed. How it worked: - It did not work for me. I kept photo diary of my acne and my acne got much worse - got many more spots/cysts, more inflamed, painful, with big spots sensitive to touch which would hang around for weeks. - Skin got at times too dry and hurt. My lips got cracked when I applied the product to spots under my nose. I used this product in the winter and moisturised my skin, but weather might have contributed to skin being dry. - When applied on broken skin, it hurts and does not seem to allow skin to heal. My spots were often too sensitive to touch and bursted during washing/removing make up. I still put the Aknemycin on these bursted spots but it did not calm it down (as for example Dual gel used to do for me). it says not to use it on broken skin, so this is not a surprise. - I kept with Aknemycin for 6 weeks as I did not know if worsening of acne was purging phase or not. My dermatologist did not know why Aknemycin (and Skinoren) did not work for me and seemed to make my acne worse and I am now trying Doxycycline and Rozex - both antibiotics. Good bits: - the application is easy and applicator makes it easy to apply. - After about 4-5 weeks, acne seemed to be a bit calmer after using Aknemycin during the night, but spots still continued to develop
June 17, 2016
Worst acne medicine I've ever been on
Two stars only because I like the way the bottle works for application. I used this for almost a year and I had absolutely no improvement. If anything, my acne became even worse. Aknemycin made my skin oily at itchy, not to mention it also smelled awful and if you accidentally get some on your lips, you'll be tasting it for the next couple of hours. Also if you have any open wounds (from a recently popped pimple or even from shaving) this medicine STINGS like no other. I wouldn't recommend this to anyone.
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August 10, 2014
Aknemycin
I've tried just about everything over the years. Roaccutane helped a lot and lasts unlike anti-biotics. When I do get the odd breakout i used to use Isotrexin Gel as instructed by my derm. (not had to use it for years) Right now that is not available in the UK so my doc prescribed me this. I noticed an improvement within 48 hours. I guess retinoids just suit my skin type. What i must stress is that LESS IS MORE with retinoids. They do dry out the skin and that can make things worse. I was advised to use it once a day, a thin covering on effected areas, and not everyday. If your skin feels really dry take a day off. Let your skin adjust and get used to it. Then you can build up the frequency to everyday, then twice a day if your skin is reacting well and needs more. Go slowly and the results can be really good with these type of treatments. My wife doesn't even realise I used to have bad acne problems :) I hope this advice helps.
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January 2, 2012

Pros:

No blackheads

Cons:

Made me breakout
Red, really dry, painful skin ~ Don't use it for one day and skin becomes incredibly oily
Did nothing for current spots

Unless you have light acne or very light acne, don't bother using it, it really did nothing for me at all.
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October 20, 2011

Pros:

Cheap (NHS prescription in the UK)

Cons:

Made my acne worse, still after 6 weeks

Months after I had to stop taking the Dianette which had worked wonders for my back and chest acne, my skin got gradually worse again. My GP prescriped me the Aknemycin Plus topical solution. Quite difficult to apply to the back, I tried it anyway and didn't see any positive effects so far. In the last few weeks, I realised that my skin got even worse, I have new angry red pimples which I didn't experience that badly before. People often write about initial bad outbreaks and then an improvement but so far I have been taking this stuff for 6 weeks now and there are no signs of improvement whatsoever, just the opposite. My skin is in such a state that I'll go to a specialist next and will ask for Accutane. Aknemycin seems to work for some, maybe it depends on how severe the acne is. So please don't be discouraged, it might help you, I just wanted to add that this was not the case for me.
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October 28, 2009

Pros:

Easy to use as it is in a roll on container and skin overall looks alot healthier and feels very smooth

Cons:

Skin slightly dry and can feel tight but nothing I can't handle.

I have been using this for the past month with Erythromycin and I can tell you my skin is looking very good for the first time in 5-6 years of struggling with acne. I use it twice a day but before hand I always wash my face with a gentle facial cleanser to remove dirt, then pat dry with a soft towl and finally apply the Aknemycin onto the affected areas. It just feels a bit tight and dry during the first few minutes of applying it to my face and after maybe 10 to 15 minutes you skin feels normal again. It's smell isn't the most pleasent especially if you have to apply it under your nostrils as it smells like pure alcohol and makes your nostrils feel tingly. Just a warning to the males and possibly some females :P. Try not to apply it on wounds after shaving it really does sting.
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June 20, 2009
v been usin this for about a month nw, and my skin is at its worst in my opinion, uneven tones, dryness, etc but after readin other people's reviews i gues tht is normal, hopeful i wil notice a change soon,fingers crossed.
May 28, 2009

Pros:

I have been using it for a month and saw a dramatic difference after 2-3 weeks of everyday use. It clears up the skin, kills bacteria that cause acne. Has a mild peeling effect therefore the acne scars disappear quickly. Skin is a lot smoother.

Cons:

It does irritate the skin especially in the first week. Skin may become red and is sensitive to the sun. Stinging sensation (don't use it on open wounds!!!)

I tried almost everything - antibiotics, contraceptive pill, roaccutance (although decided to quit it after 3 weeks=I guess does not count), various creams (BP) and microdermabrasion. I was not convinced this would help but decided to give it a go. I was desperate for a miracle. And this proved to be one. I noticed huge difference after 2 weeks. I have a lot less skin bumps (that later become red swollen and painful spots), skin is clearer and smoother. I have not had a pimple for a week - a miracle as I used to have a new one each morning. I will continue for another two or three months and then will have some microdermabrasion to get rid of scars. I may have to come back to it again.
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April 12, 2009

Pros:

It seems to purge all those infected pores. Hopefully, it gets better.

Cons:

You break out. A lot.

My doctor prescribed this to me after I started breaking out badly after using Murad and mineral make-up. I've only been using it for a month. Needless to say, it causes one to break out quite badly (for me, it was/is terrible on top of those that I suffered earlier). I seem to be getting pimples everywhere, as well as dry, red, peeling skin. After reading previous reviews, I suppose this is an initial expected stage, so I'm gathering my courage and patience to wait it out for the next few weeks.
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November 5, 2008

Pros:

After the first month it does start to work. It reduces redness and oilyness as well as starting to clear up the acne.

Cons:

It stings and makes your skin tight. Also, you can't stop using it when you think your acne has gone. It will come back!!! The treatment makes your skin very sensitive afterwards, so be careful when using other products, such as makeup & moisturisers

The bottle applicator is fantastic as it is very hygeinic and easy to use. It does sting a lot, however it is worth perservering. You will notice that your skin seems to get worse in the first month but don't worry because after the initial month it will improve. Once it does start to work it is great. This product does make you peel. It says in the instructions not to use any exfoliatives whilst using this product, however i did, this got rid of any dead skin cell and the itchiness that does occur with Acnemycin Plus solution. I also used a LIGHT, NON OIL based moisturiser whilst using this product, but don't go mad with the moisturisers as they will just make the skin worse. Now my skin has improved i still use the product everyday but only once a day rather than the reccomended twice a day. I have very few spots now but quite a few scars which i am using bio-oil for. But again, do not use this untill ALL spots have gone.
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