I am on day 18 of accutane. So far I have noticed a ton of breakouts on my neck and shoulders. Luckily it's winter time so I can cover them up with clothes, but they are extremely annoying and painful. I have already started to notice a fair share of side effects as well. Among these are bloody noses, joint pain, and the infamous chapped lips. My sister went on accutane about four years ago, and it did wonders for her acne, so when I started noticing that my acne was getting out of hand I knew that accutane was the right way to go. Just got to make it through these six months...and then hopefully I will have my much desired clear skin. We'll see.