I was taking 25 mg spironolactone from January to June, then I stepped up to 50 mg in the summer and started waking up with a puffy face and eyes every single morning. I felt extremely dehyrdated and my face and eyes looked dead, I ended up going back to 25 mg for 2 months then stopped the drug completely because I was tired of taking too many medications. I also take Yaz birth control pills. Its been a little over 2 months off Spironolactone and I still have the same side effects; puffy face every morning, extreme thirst and dehydrated feeling. I feel like my eyes swelling every morning is stretching them out and making them look so sold, my eyes look droopy now and wrinkly now. Ive tried to sleeping with bunch of pillows but i still wake up puffy and drinking massive amounts of water doesn't help. Anybody experience the same thing or have any advice?