I have very carefully watched my skin. No new breakouts. Havent broken out during my monthly in a while! Skin is neutral. Im still waiting for my blemishes to leave. I have been on Ziana for over 2 months & its been working since the first time i applied it. I hv maintained not wearing makeup because i feel as tho it may jus clog my pores. So far so good. I apply ziana every nite & acanya every morning. Pea sized amount. Moisturizer before i leave home.