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First (Real) Entry 2/14/14

So, more about Spiro and Doxy.

FYI: this post is a bit messy, I promise I'm not usually this confusing.

I'll post pictures later, but basically, I have cystic acne on the bottom half of my face--mostly concentrated on my lower cheeks, but also some on my jaw line and chin. My nose and forehead are actually quite nice looking.

So I went to an endocrinologist and got my hormones tested. Everything is good except my DHEA, which is way high (darn adrenal gland, malfunctioning). According to her, it is probably causing my cystic acne and other not-relevant-to-this-forum health symptoms.

In January, I started on Spironolactone (January 14th, to be precise--happy one month anniversary to me!!!). 25mg once per day. I did that for 2 weeks and then went up to 50 mg. Tuesday was the start of my 3rd week on 50 mg and the start of my 5th week overall (hopefully that made sense).

Not gonna lie--I absolutely HATED Spiro at first. I had an initial breakout and my skin was so dry it was turning white and flaking off. Partially, I attribute that to the fact that I live in a very cold and very dry climate. But I think it was also the diuretic effect, cause I was constantly dehydrated too, and going to the bathroom a lot.

However, my skin started getting a bit better, surprisingly soon.

When I went up to 50 mg, it was the initial breakout and dryness effect all over again, only this time it was not going away as fast. So when I went back to my dermatologist last Friday (2/7/14), he started me on 200 mg Doxycycline, 100 in the morning and 100 at night. He said we're just 'biding time' for the Spironolactone to really work, so hopefully this is a temporary thing. Fingers crossed.

So far, Doxycycline is really helping. Less redness, less cysts.

He also took me off Tazorac since it's really drying and not helping my cysts anyway. It feels weird to be off it though......I've been on one topical or another since I was 11 years old (I'm 17 now).

Unfortunately, I have 2 new cysts today, one on each cheek. I'm hoping they'll go away before they get full blown. Otherwise, my skin is actually really smooth, which just a couple 'old' cysts in the process of healing.

And perhaps the new cysts are just cause of my crappy eating habits this week......Valentines Day brings too much chocolate. Ugh.

Side note: I know my Spiro dose is kinda low......I'm on another medication that has a high risk of reacting badly with Spiro, so I have to be careful and get my blood tested a lot.

In case you didn't want to read all that, here's a summary:

27 days on Spironolactone, on 50 mg once per day right now.

7 days on Doxycycline, 200 mg per day.

Clearasil face wash at night, just water in the morning.

Cetaphil moisturizer.


Hey there! I am also a Spiro/Doxy user and at 50mg. I am also on Yasmin, which cleared me before so I have much faith in the low dose. I too had a bad IB weeks 3-4, the 3rd week was inflammed so I went on doxy and the 4th week all closed comedones that came out of nowhere. Well I guess not nowhere. But anyways. I've been slowly clearing those closed comedones. Have had a few steps forward then a few steps back this last month, but I finally finally think things may be getting better in this 3rd month. I am interested to see how you do and when you decide to wean off Doxy. I think I am going to stay on it another 2 months and slowly slowly slowly wean off. Like snail pace :) Hope your week is going well!


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Thanks for sharing your experience--I'm always happy to hear from another acne sufferer in a similar situation. Closed comedones are the worst!!! I'm glad things are getting better for you. I'm not even THINKING about going off Doxy right now, but if/when I do make that decision, I'll definitely write about it. :)

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