Ok well my journey with spiro has been a long one. I've been on it now for over a year and a half. It helped me dramatically... changed my skin from being moderately severe to mild/moderate. Probably had an 80% improvement.. However, I yearned to be 100% clear. I finally added birth control, ortho tri cyclen, and also added differn .1% gel. Differin worked great for me in high school, but had to stop because I no longer had health insurance. Well, one and a half months into these new additions and I am 100% clear, and have been so for a week (and I'm on my period, no less!) My skin tone has dramatically improved, and my skin is great, no clogged pores, no whiteheads or blackheads... this has never happened to me before. I've also dramatically changed my diet in the past two months. I cut out gluten, dairy, and eat mostly leafy greens and daily green smoothies. I have never felt better or more confident in my life. Spiro is a wonderful drug, guys, and it helped clear me so much, but only now am I 100% clear. Spiro was a great step in the right direction though.