I'm having a better morning. I've noticed that accutane seems to interact with my anti-depressants, b-complex and I'm more sensitive to sugar so I think I'm stopping the vitamins, decreasing one of my anti-depressants, reducing sugar and take accutane separate with any medications. I feel less depressed so I want to make sure I'm not taking too many meds that'll make me sick. I tend to react to medication quite rapidly and I have to respond to it as it comes. If I get depressed I'll up my med again. I really want to take accutane and I'm willing to change the way I do things to accomplish that. I would even resort to taking an anti-anxiety med to counteract any anxiety that I get from accutane. The psychological impact is greater than the setbacks that might be given. I'm taking the accutane today at around 4pm. I hope it's enough to make it bearable.