Almost 3 weeks into accutane, dry eyes and lips becoming a bit more drier. Sore shoulders, not sure if this is a joint issue. But my complexion looks good, the cystic pimples i had last week all dried up so fast, just some flakey skin by these but thsts it. Just drier than usual, no new pimples or anything. wow....amazing ...oh and ive been drinkning alot of water , taking primrose evening pills, thirsty ALOT! hope I dont get any bad side effects, I can deal with these. No signs of depression at all either. Very happy!!!