So at the moment I am about 3 weeks into taking 408mg Lymecycline, and my acne is probably worse than ever!!! I know that i should be waiting it out because my derm recommended 10 weeks of dosage, however Im just feeling incredibily self concious. When i last saw my derm (3 weeks ago) he said that i should do a second dosage of roacctuane. My thoughts on it are completely 'iffy'- yes- it made my acne so much better after around 6 months, however those 6 months were unbearable for me, simply because I already suffer with depression. So when my derm recommended taking it again I had to turn it down for my own mental health... I have booked an appointment in with my GP instead for Thursday to see if she can help or has any other suggestions.