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Entries in this blog

 

Indole, Tryptophan, Glyphosate, Antibiotics & Microbiota

It seems the more I learn about the microbiota and common herbicides/pesticides the more interesting things get.   Glyphosate is in a common herbicide as you know (Roundup). But the interesting thing about it is its inhibition of the “shikimate pathway” in bacteria. Harmless? I don't think so. Here's why:   The shikimate pathway is the pathway in microbes that synthesize the amino acids tryptophan, phenylalanine and tyrosine. While thinking about depression, acne and gut moti

FvckAcne

FvckAcne

04/04/17

 

Mucosal Immune Barrier

Turns out the mucus barrier in the gut is influenced largely by the microbiota. I keep hearing about “leaky gut” but I think apart from cell permeability... what if there's been a loss of key mucus-stimulating microbes?   There's another post on butyrate and SCFA that somewhat hints that they increase mucus production. There I talk about how I never had acne until my appendix was removed and that in studies of the appendix, they often find Akkermansia muciniphila – a known mucus-stimul

FvckAcne

FvckAcne

04/03/17

 

Probiotics and Microbiota

Here's my thoughts on the microbiota as of late:   I have my doubts about the importance of lactobacilli.   I've never really seen any difference when taking probiotics. But I'm interested in the Clostridia. They're spore-forming soil organisms. Some research even suggests that Faecalibacterium prausnitzii is one of the most prominent gut bacteria accounting for something between 5 and 20% of microbiota. What's interesting about them though is that they adhere close to the gu

FvckAcne

FvckAcne

03/27/17

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