First Week of Accutane- I am on 40 mg twice a day. The first few days I did not see much of anything...then BAM...my lips felt like they were melting!!! The first week was a but rough for me. My body was trying to become use to this BIG change. Week two- I am just starting off week two. This sounds a bit odd, although my lips are much better along with my face. I am itching really bad and my skin is peeling like crazy!! I will get back to everyone as soon as my second week is over!!!! Wish me luck!!