I'm 46 and have had acne since i was 14. I've tried everything out there and nothing has worked or lasted. this includes Accutane, antibiotics, sulpha lotion, benzoyl peroxide, laser, peels, and tons more. accutane worked for a few years but after the birth of my son, acne came back in a fury. i went on accutane again, but lasted a few months. This product with a combination of other products has helped resolve my problem. In the morning I wash my face with physoderm ph reducer. Then i apply a thin layer of reversa 8% glycolic cream (wait 15 minutes after washing to apply). Then i apply a second layer of Eucerin 5% urea face cream. Since glycolic can be irritating to the skin and also dries it out, this is the best cream that i have found to give me intense moisture without break outs. in the evening, i wash my face with sebcur 4% glycolic acid. Yes, this product is meant for dandruff, but the 2% face wash that are available on the market simply was not working. i needed something stronger. once my skin is completely dry, i apply .5 retinol cream to my entire face and add a second layer of eucerin 5% night cream (very very hydrating). Note that at the beginning, i had to apply the glycolic and retin a every 3rd day to give my face a chance to adjust. eventually it was every day without any irritation. By the 3rd week into this treatment, all pimples on my chin, cheek and nose disappeared. I had a few break outs and by week 6 nothing. I'm now on week 10 and still nothing. It is so nice now to get up in the morning, touch my face and no pimple can be found! its a miracle and i'm crossing my fingers that it will continue to last. the main benefit of this regime is that your skin will shed quite a bit bit without any irritation. however, it is important to manually exfoliate your skin every second day. The best exfoliating glove on the market is Renaissance. it costs more, but it can last several years (make sure to clean it on a weekly basis). i also purchased a small microdermabrasion machine and use it once a week for more intense exfoliation. This really helps with removing a lot of dead skin. Today, my skin is amazing. Many of my acne scars are barely noticeable. They are slowly disappearing and if you are in your forties, fine lines are also considerably reduced. My colleagues cannot believe how good my face looks, they indicated that i look so much younger and healthier. I wanted to share this regime as i have tried pretty much everything that exists out there.