Page 5 of Spironolactone reviews

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Active Ingredients:
25 mg, 50 mg or 100 mg of Spironolactone.

Inactive Ingredients:
Calcium sulfate dihydrate, colloidal silicon dioxide, croscarmellose sodium, crospovidone, hypromellose, lactose monohydrate, magnesium stearate, peppermint flavor, polydextrose, polyethethylene glycol, povidone, pregelatinized (corn) starch, sodium lauryl sulfate, titanium dioxide and triacetin.

Items marked with orange can be irritating and over-drying, especially to acne-prone skin.

The list of ingredients above is provided for informational purposes only. Always check the actual product label in your possession for the most accurate ingredient information due to product changes or upgrades that may not yet be reflected on our web site.


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You need a lot of PATIENCE with spironolactone!
Reviewed on December 11, 2014

This medication takes a bit of time to work. for me personally it started to kick in fully at 8 months. I had absolutely no break outs by the 8th month. for some people they see full on results between 3-6mothns. This medications works for hormonal acne but you need a lot of patience with it , Do not give up ! Give it up to 8months to see if you see a change in your acne. Another thing is you must drink lots of Water ,you must train your body to love water.

My dosage was started at 100mg then upped to 150mg a day around month 4,

I also got on Yaz birth control once I started spironolactone.

For topical I was prescribed fiancea to fade my acne hyper pigmentation , and to spot treat my acne.

by LRH714 on 12/11/2014 20:37
What was the process for getting a prescription for spiro? Did you have to do any initial testing or bloodwork? Have you had to do any since? Also, did you get this from a dermatologist or your general practitioner/OBGYN?
by bm93 on 12/12/2014 05:16
You can get it prescribed by a dermatologist
by Sgala3 on 12/26/2014 19:50
I got my prescriptions from my dermatologist and also yes I do get my potassium levels checked regularly
25 with moderate to severe cystic acne
Reviewed on December 10, 2014

I have been using 100 mg of sprinolactone for 14 weeks and I couldn't be happier with the results. I use it in conjunction with birth control and Aczone. I have had mild acne on and off since I was a teenager but over the past 2 years it developed into moderate and at times severe cystic acne with my skin not being clear for months at a time. I had tried everything else, antibiotics, topical creams, etc. and nothing was working. After starting spironolactone I slowly saw results but did have a cluster breakout of pimples on my cheeks about once every 3 weeks at the beginning. However, my skin has been clear for the past month and I keep telling my sisters who suffer from the same kind of acne as me to get a prescription! No major side effects except for feeling dizzy when I get up sometimes if I am dehydrated. Stick with it, it's worth it!

by bm93 on 12/20/2014 21:56
What do you use for face wash and mosturizer?
Starting this treatment next week
Reviewed on December 10, 2014

**will keep updating as I go**

I will be getting married in 9 months. That being said I'm hopeful that'll give my skin enough time to a just to this medication.

when i was in my teens (14) i started suffering from acne. i mostly had it in my T-zone with the occasional cystic out breaks on my forehead. at the time my reg. doc gave me a scrip for Duac. this ended up being the wonder drug for me! after being on it for two years, i noticed i had "grown out" of my out breaks and was easily treated with otc so i stopped taking the duac.

Fwd to around 20 and i was getting more mild out breaks around my cheek area, my doc then decided it was hormonal and put me on a low dose Birth control pill to balance me. This set my skin over the edge! I've never been so badly and painfully broken out in my cheeks while on the pill. I had black heads, white heads, and cystic acne. I was on the pill for 3 months trying to give it a chance. i couldn't take it and stopped taking it. i then requested to be put back on the duac. unfortunately, duac isn't working as well as it did. it cleared up the black heads and the white heads about 85%, but not the cystic. my cheeks are starting to get a couple of "pits" and its depressing to look at. no amount of make-up will hide them... on top of it my skin has been very oily and my pores are enlarged. reading other reviews on this drug is giving me hope. most everyone else who is posting reviews on this, were having the same problems. my acne isn't as bad as most. i usually have around 2-3 cysts in my cheeks, the duac is keeping the white heads at bay. the cysts come around 1.5 weeks before my period and then finally subside after. then i'm for the most part "clear" of the cysts for about a week or so, till the cycle starts again. I'm nerves about the huge out break everyone describes, but I'm hopeful by summer my skin will finally be clear and i don't have to worry about doing a full face of make up any more.

Hey I updated my review! So happy!
Reviewed on August 30, 2014


I am 25 years old, and when I was sixteen I got bad acne on my back. Went to the dermatologist, and it cleared right up. Then after that I was fine, no real problems. Then I hit 22, my acne is not awful, its moderate. It feels awful though. I always pick at them I can't help it. So at 22, I was put on birth control to help, and antibiotics, then retin-a. I read it can take up to a year to work, I used it off and on for the first year, then I decided to get serious so I used it religiously, nine months go by and no change. I get maybe four days out of the month with clear skin. I noticed it got really bad the week before my period, and during. I changed my dermatologist about a month ago. I told my new doctor that I felt like my old doctor would just put me on a different antibiotic at a higher dose, and never really asked my too many questions. He said he didn't understand why I was on retina, because he said it was for smaller pimples, and black heads. He prescribed spironolactone, because my acne was is the right place as hormonal acne, and it corresponded with my period. I am already on birth control, so he said to stay on it. He also paired it with minocycline antibiotic to help with the initial breakout. He told me the first week to do 1-2 25 mg pills a day of sprinolactone, then the next week up it to 2-3 pils, then the final week to take 4 pills, so 100 mg. He left it up to my to decide what dose my skin responds to the best. I am on the first day of the 100 mg week. I am still in the breakout stage, which isn't any worse then one of my bad breakouts. I am really hopeful about this. He told me to come back in November to check in, and see if it was working. I will update my post then. This dermatologist was much more attentive.

They that was three months ago above ^^^^^^^^^^

I am updating my review. Going from 3 to 5 stars. 12/08/2014

If you want my acne background scroll down to the August posts, and there it is. I have been on Spironolactone for three month's. I see a huge difference. My acne corresponds with my period. Last month there was still a breakout the week before my period started. This month nothing, no big breakout. My dermatologist wanted to be proactive so he wanted to do another check up 3 months after I started. Which was around my last period. Which was before thanksgiving. I still had a breakout going on when I went to see him. So he added a topical creme, to my birth control, and Spironolactone. I don't know if the spiro kicked in, or the topical put me over the top. Its probably a combination of both. My skin has been clear for three weeks now. Which is unusual for me. I only have moderate acne, but I still got pimples every week. Nothing since I started the topical. Its called AcZone, apparently is pretty expensive if you don't have insurance. My insurance covered the whole cost though. When I tried to fill it at the pharmacy, the girl said the insurance won't let me fill it, because they want to see I had tried other topical's. So she called the insurance and ask them to override it , because I had tried other things. It took only about ten minutes. I am pretty sure all three things I am on has helped me become totally clear. The birth control, and spiro helped the hormones. So that treated what was wrong on the inside, then the AcZone just put me over the top. I would recommend all three to you guys if your breakouts correspond with your period hormones! Birth control was free with insurance, AcZone was free with insurance if you have met your deductible, and I think spiro was 5 to 10 dollars with insurance! Oh and I didn't experience any of the negative symptoms on Spiro that some people have. No tiredness, no dizziness, or I have read some of you have had weight gain? I haven't gained a pound. I am really lucky, because I know all our bodies are different, and respond to things in different ways. It also only took 3 months to kick in for me, that might be because the other stuff helped too.

by Chelseakayheaton on 08/30/2014 01:02
I have never tried accutuane, because its scary, and I don't have severve acne, just moderate. I am really hoping this solves my skin issues. I also tried all natural things like taking a supplement, eating better, and having a strict face washing schedule. My problem was obviously deeper then superficial causes. Topical's didn't really work all that well for me.
by ang9243 on 08/30/2014 21:06
You have to keep taking it faithfully and you will see results, but you must be patient. Honestly, patience is the important thing here. I've been on Spironolactone for 17 months now and I have seen and still great results. I can't feel any better the side effects are totally worth it.
Feeling like a walking dead
Reviewed on December 4, 2014

Background: PCOS, so hormonal acne for 100%

Have read almost every post and review about spiro on this forum, so the sane me know sometimes spiro can be slow. But going through all these I can bearly think rationally.

2 mo ago I went on spironolactone, 50mg per day. Stopped getting blemishes for 5days but then broke out again. Stayed at 50mg for 3 weeks and got bumped up to 75mg. Stayed clear for 3 days but broke out persistently again. One week later got upped to 100mg. Stayed clear for 3 weeks and I genuiely thought this years long nightmare is over. BAM breaking out nastily again. Today marks 2mo starting spiro and 3weeks on 100mg. New ugly spot every day. My skin problem is consuming my life. And I cant imagine how I would really have clear skin one day.

Still hopeful
Reviewed on December 5, 2014

Going to give it 3 stars because I want to be hopeful! Ever since starting the Spironolactone, it seems to just keep getting worse and worse. Now huge cystic acne under the skin and it's getting red, and seems more irritated. I will keep holding out, because I know it's all hormonal. I don't think my period helps when it's that time of month. However, I really am getting depressed over it, and want to cry. My kids want to go out and play, I don't want to go do anything. I'm getting so sad, I feel so ugly. The package says to drink alot of water, and I have been to see if it helps. NOTHING IS WORKING. Anyone else have any hope? I started the pill on November 17th, 2014. I'm now learning, from reading different reviews it's going to get worse before it gets better. This is just disheartening, however hopeful all at the same time. I don't know how to feel. I'm really upset about it, and cry everytime I feel how bad my face is.

Hope this all pans out, and I don't have to wear makeup anymore.

by gmailgrl on 12/05/2014 04:08
Took 6 months before I saw the difference. was well worth it tho!
by Charnick on 12/07/2014 12:30
I have been on on several years now with great success. It took 4 months before everything finally cleared up. 50 mg 2 x daily. My Dr. told me it would take several months, well worth the wait!
by sladnacne on 12/08/2014 22:07
I started mine on November 22 and am going through the same thing. Even though my acne has been this bad in the past, it hasn't gotten this bad in a while and is a very sobering reality to deal with. Everyday is an emotional struggle to not let my skin bring me down and maintain hope that one day it'll be better, but I can only describe how I feel when I look in the mirror as painful. I have started to notice that if a pimple appears and I don't try to pop it like I always do, that it disappears more quickly than in the past. This is giving me SOME hope. Everyday is hard just to get up and go through the painstaking process of trying to treat and cover existing pimples while trying to cover old ones. I would give my right arm for this all to be over without having to wait out these painful few months
Reviewed on November 22, 2014

I have never posted on here before but feel like I am at the point to do so. I am 29 years old and battling with hormonal acne since I was 12. As we all know, it can really take a toll on your self confidence and it has made me so insecure over the years. I have tried numerous things along with everyone else and in the past Proactiv worked for me but now makes me skin burn and no longer works. Birth control also helped me but I stopped taking it when it was getting too expensive. About 6 months after I stopped my face started breaking out like crazy possibly worse than I can remember. I tried clarisonic, multiple cleansers, to no success. I finally broke down and went to the dermatologist hoping for a cure and interested in Spironolactone because of all the good reviews. She started me on Spiro 50 mg for one week then bumped me up to 100 mg daily and it has only been 2 and a half weeks since I have been on it. I am also on Atralin gel at night and Aczone in the morning. I feel like my skin is very slowly improving but it is hard to tell and I know it takes time with this medicine so I will continue to be patient. I hope for the day I can wake up and see no acne looking back at me. I seem to tolerate the medicine okay so far with no crazy side effects.

by KCsr2 on 01/06/2015 14:20
Wanted to update my review as I know the importance of that from reading everyone else's... I have now been on Spironolactone 100 mg for 9 weeks. I went to a recheck last week and at that time my skin still seemed awful, I couldn't tell if it had improved much or not. I could tell there was much less oil as I used to use oil blotters before on a daily basis and now hardly ever have to reach for them. About one month ago, I started up birth control again- Lo Loestrin Fe, due to having a period every other week from Spiro. I also have cut out coffee a few weeks ago, and recently have stopped dairy as well as I seemed to notice new pimples daily after a heavy pizza weekend. After meeting again with my dermatologist which was an early recheck, I got my potassium levels checked and discussed with her to stay on the Spiro at the same dose, but also was given Omnicef, an antibiotic to help with the inflammatory lesions. She also re-emphasized the importance of retin-a gel at night and aczone in the morning which I had started to use sparingly due to my skin drying. I started that up again and switched to Veltin which is a less harsh retin-a that also has Clindamycin in it. Somehow, the consistency of this combination and my current medicines have led me to see great improvement in this past week. My face is getting more smooth and pimples that were lasting for weeks are starting to fade. I am hopeful that this is not temporary and will continue to improve and get better and better until I am completely clear. Prayers and thoughts with all of you going through the same thing! It is a mental condition for me as it has affected so much of my life and I can't wait for us all to be confident in the near future. I will continue to provide updates.
by KCsr2 on 02/01/2015 22:04
12 week update! My skin is looking better and better. It is so much more noticeably smooth when I wash my face. I have a few pimples but all of the others are fading thus I have red marks that last forever but makeup helps hide them. I am feeling more confident and hoping for continued improvement. Quality of life is improving too! I am also still on antibiotics and topical creams as mentioned in previous post. My only concern is every once in awhile I am experiencing heart palpitations, could definitely be stress related but it scares me because of the concern for hyperkalemia and low blood pressure. My potassium levels were normal a few weeks ago though. Anyone else experience these? I pray for continued clearing of my skin!
by KCsr2 on 03/08/2015 23:45
I'm past 4 months now and feeling great! Skin is mostly clear with the occasional pimple but overall dramatically improved. So much smoother and red marks are fading. I did a six week course of antibiotics and still trying to keep majority of dairy out of my diet. Still on Spiro 100 mg once daily. I am now using nerium at night to help with the lines/marks/scars etc. Just wanted to give a positive update! Still can't wait for the day where I don't have to wear makeup to feel beautiful.
22yo on Spiro
Reviewed on November 21, 2014

I've been on Spiro for 41 days and I'm just now seeing the results I'd hoped for. I have one pimple on my cheek but my entire face has cleared. I used to have cystic acne all around my mouth jawline and cheeks. I was on 100mg for 1 month and just bumped up to 125mg the last 10 days. I would recommend to anyone struggling with acne!! It does take time though and I am still hoping for more improvement over time.

by bm93 on 11/22/2014 01:56
Im so glad to hear that spiro has helped there anything else you are on or taking with spiro and I'm on 50mg a day been on it for 24days now you think it just takes time to see results?
Feeling uneasy...
Reviewed on October 2, 2014

I have never really had Acne until about a year ago. After reading several posts I think the factor that caused me to suffer such a sever breakout was going on and off of birth control 3 times in the last year and stress. I would have to say the end of 2013 and most of this year has been extremely difficult.

A little background about me... I am almost 29, and have suffered with thyroid disease for the last 14 years having been diagnosed with hyperthyroidism at the age of 15. Then having radioactive iodine therapy at age 17. Which sent my body into a complete shutdown causing my thyroid to become hypo. For a really long time I was taking synthroid and it wasn't helping me at all. I was gaining massive amounts of weight, extremely depressed worst part was the excruciatingly unbearable pains in my joints, no energy couldn't stand to be cold, always getting severe colds almost pneumonia all of the time. Until about 2 years ago when I found this wonderful doctor who in a way saved my life. Since then I dropped all the weight, feel happy and healthy. No pain and then this.......

About a year ago my skin went crazy. My cheeks and neck became inflamed with nodules, cysts, and huge disgusting white heads. Then the picking and popping began. Everyday it was another and another and there wasn't one day that went by that I didn't get another one. I started seeing a derm by my office who would give me creams, washes and more and more antibiotics. for months doing everything as prescribed and not seeing any light at the end of the tunnel. I changed my diet (which I was already eating very health to lose the weight) . I used organic this and no dairy and went for facials, even did Photodynamic therapy with and without levulan leaving more acan and now holes, scars and dark spots.... You name it I did it. After not seeing any results with the first derm about 2 months ago I started seeing another one. She started me the same way blu U, anti biotics, aczone, acyana, epiduo, etc, etc... Last month I went there just heart broken. I was about to host my boyfriend's 30th birthday and I couldn't even bear the thought of going into public like this. All I wanted to do was crawl under my covers and hide. The derm said lets try spironolactone.... She prescribed me 50mg's 2 times per day also kept me on minocylcen 100 mg once a day and creams aczone in the AM and epidou in the pm. wash 2 times per day with neutrogeona ultra gentle hydrating cleanser and cetaphil oil control moisturizer.

Today marks my one month on this medication. The only side effects i experienced were in the first few days a little lightheaded and dizziness.. that has pretty much subsided, I am very thirsty and Pee a billion times per day. I did have terrible initial outbreak in the second week which still has not gone away. I have ugly cysts on my check but I have noticed the amount of acnem i normally get is reduced and the length of time a pimple takes has increased. I don't know how much more patient I can be. M skin is still oily and I don't want to wear make-up but walk with my head down out doors because its just so heartbreaking. I am supposed to go back to derm on Monday. Hopefully something with give for me soon. My heart is just so heavy I can't even look in the mirror. If i have to go somewhere i have to cake on pounds of make up and that doesn't even help. I just want to feel pretty again. All I do lately is cry because I have done everything as directed and just nothing. I hope everything I read is true and I start to see improvement soon. I don't know how much more I can handle.

I will update again in a few weeks. Good luck everyone out there going through this.

by ang9243 on 10/07/2014 02:27
You just have to keep taking Spironolactone you have to go it more months.
by Downbutnotout85 on 10/07/2014 13:55
@ang9243. Today is the first day I don't have any new acne and my skin is beginning to heal. I am praying.
by ang9243 on 10/07/2014 21:36
@downbutnotout85 you should be fine you just have to let the Spironolactone do it's work because it works once you make it a habit of taking it every day. You have to give Spiro at least a year or something close to a year before you start seeing clear skin I don't even have to put on makeup anymore at least not pounds like before I just put on light stuff because my skin is so clear now it's amazing. I've been taking this for 18 months now (1 year and 6 months) you just have to be patient sometimes the side effects can be a pain in the ass that's all. 😞
by Shlebs on 10/10/2014 17:47
Listen to me...please do not give up! Your review has inspired me to post one of my own (it will be right above yours), because I was feeling EXACTLY the same as you are one month in. I've now been on 100 mg of Spiro for about 3.5 months and I haven't had a breakout in 3 weeks. Truly, how Spiro affects people is so may take a couple weeks for a [very] few lucky ones, and it may take up to 8 months or beyond for others. I'd say between 3-4 months to see a drastic change is typically average. I am confident this medication WILL help you, just let it do it work. :)
by Downbutnotout85 on 10/20/2014 19:13
So today was not such a great day. I woke up with 7-8 inflamed bumps. I ended up crying at my desk a couple times following my derm appointment earlier this morning. I have now been on Spironolactone for 6 weeks. I am just beside myself. How much longer :..................( When will I get to wake up and look in the mirror and just feel the weight of this illness lifted from my shoulders. It doesn't need to be perfect but just be able to go out without looking like pizza face.
by ang9243 on 10/22/2014 21:44
@downbutnotout85 I'm sorry to hear that you're battling right now, but you have to keep taking it to see results. It takes more than 6 weeks to see results. You just have to hang in there.
by jenblue on 11/05/2014 04:53
look into getting a hydra-facial at the dermatologist. Not pretty or relaxing but in a few days your skin will feel much better. I had an infected cyst and it is clearing up. The dermatologist will extract alot of the pimples but it will heal. please look into it, it is somewhat expensive but i swear it has helped me go through this as well.
by Downbutnotout85 on 11/05/2014 17:55
I just want to give an update.. Felling better I have 1 cyst and red marks and scars but not even one pimple. I have reached my 2 month mark and am finally beginning to see what everyone has been talking about. I spoke with my Derm she said that peels will help significantly with marks and scars and greatly improve my skins texture.. They are so expensive so I will have to figure something out. But I am feeling positive, hopeful and for a change at ease. Good luck to everyone out there if your suffering. No one should have to go through this!!
works only if you have pcos, hormonal acne. no permanent fix
Reviewed on November 2, 2014

I was diagnosed pcos 2 years ago and they put me on this drug. Worst mistake of my life.

I've recently discovered( change doctor)I don't have any pcos( weight 110 lbs, height 175cm, no hirsutism, perfect blood exams,no insulin issues, perfect testosterone and dhea levels even before this cure, no issues with menstrual cycle)and the previous doctor was totally wrong and gave a wrong diagnose.

My acne was never completely cured while on this drug despite being on 100 mg per day and despite my acne was mild, never more than 5 pimples/ papules per time.

Beware of the side effects which aren't mentioned like drying of the skin and scarring.

My skin became superdry in the last few months but my acne is still there. I'm weaning off of it but it's still dry.

Scarring, which I never experienced before, is caused by dry skin and the fact that skin wounds take more time to heal if the skin is dry. Acne is not only caused by oily skin but it has to do with the oil and the pores of your skin. That's why you don't cure acne just by suppressing oil, because even the smallest part of oil can get stuck in your pores if they don't work properly.

Moreover this drug is not a cure for your acne, because even if it works when you stop it your acne will come back.

You'd better give accutane or exfoliators a try, this is just a waste of time and no permanent Fix.

My skin has scars now Thanks to a wrong diagnose, a wrong cure and a stupid doctor who told me to stick with it for almost 2 years.

I'm considering a lawyer and will start accutane in a few weeks.

Even my periods went totally crazy,came every two weeks, and I needed a progestinic 4 days a month to fix it. Stay away unless you have real pcos or you are looking for troubles.

by dkknaj on 12/04/2014 04:10
your crazy, spiro is the most amazing medicine for acne. stopped my oily skin and greasy hair. NO more cystic acne. You need to use a moisturizer like cetaphil daily whether you take spiro or not to help skin feel soft and heal quicker. I was on Accutane, my skin was completely peeling, lips were splitting, not to mention every bone in my body ached including my heals just touching the mattress while I slept on my back. eventually acne came back. Spiro is the only medicine that has ever made any significant improvements on my skin. I have had acne since 14, I am 47 now. If I stop taking spiro within one month break outs appear again. I do not have pcos. My periods have also shrunk down to 3 days and very mild at that.