Page 5 of Spironolactone reviews

4.2/5 - 1030 reviews
5 star
540 reviews
4 star
315 reviews
3 star
92 reviews
2 star
44 reviews
1 star
39 reviews


Active Ingredients:
25 mg, 50 mg or 100 mg of Spironolactone.

Inactive Ingredients:
Calcium sulfate dihydrate, colloidal silicon dioxide, croscarmellose sodium, crospovidone, hypromellose, lactose monohydrate, magnesium stearate, peppermint flavor, polydextrose, polyethethylene glycol, povidone, pregelatinized (corn) starch, sodium lauryl sulfate, titanium dioxide and triacetin.

Items marked with orange can be irritating and over-drying, especially to acne-prone skin.

The list of ingredients above is provided for informational purposes only. Always check the actual product label in your possession for the most accurate ingredient information due to product changes or upgrades that may not yet be reflected on our web site.

Where to buy is not associated with this product. All proceeds from links go toward maintenance.

[The prices listed above may change at any time and in some cases do not include shipping.]

Did you find a problem with this item?

 Mark product as discontinued

 Flag an error in this listing

Body acne cleared up
Reviewed on January 26, 2014

I've been using Spironolactone for four months now. I'm 21 and the moderate acne on my chest and back I've struggled with since I was 13 is finally gone. I'm getting no new breakouts, just dealing with the post acne dark spots now. I did not get a bad initial breakout like many other reviewers did. I didn't see a change in my acne for better or worse until the 3rd month when I moved from taking two 50mg pills a day to three pills a day. Every topical medication failed to make a dent in improving my body acne. The only thing that worked a little was Yaz birth control. When I realized my acne was hormonal, my dermatologist prescribed Spiro to me. This medication has given me my body back. If you're a woman struggling with body acne and you think it could be related to hormones, I would absolutely ask your dermatologist about Spiro. It takes commitment and time, but it really is the miracle drug people say it is.

Just started!
Reviewed on December 27, 2013

So far, I've been clearing up in only 2 weeks. I've had a minor breakout on my forehead, but reading others reviews I assume that's normal. Maybe it's "fighting" my acne. I'm excited to see what happens! I'm taking 50mg daily. I'll update weekly and let you know!!!

Week 3-

Breaking out even more. Cystic acne popping up. Going to start taking 100mg per day. Crossing my fingers!!

Week 4-

Face really clearing up! Remaining acne is drying out. Just keeping moisturized seems to be helping!

Week 6-

Breaking out off and on, but stopped washing my face so much (down to once at night) and it's helping! I'm not having irregular periods like everyone else either.

Reviewed on January 22, 2014

Me: College student, very fair skinned, petite, outdoorsy but not athletic.

Problem: Excessively oily (<2 hours after applying makeup), constant cystic acne lasting weeks at surface with many more lurking beneath the surface esp. cheeks and jaw, additional pimples littered randomly, scarring, hyperpigmentation. Occasional acne on back and chest.

Solution: Wash and moisturize with CeraVe products every morning and night. Worked my way up over 7 months from 50 to 150mg/day. Initial breakout for every increase in dose. Have not had a new cystic pimple since initial dose. First month saw huge decrease in oil production, back and neck clear by third month in addition to great decrease in cystic acne. By sixth month totally free of cystic acne, decreased oil w/o drying skin. That said I am chronically thirsty and peeing like a racehorse, also, with the water loss I went down a cup size which is a little sad since I am not a buxom girl to begin with, but considering that my cystic acne used to make me skip class, parties, dates etc if it was just too bad, my happiness in infinitely increased. I am no longer too ashamed to let my boyfriend touch my face, or terrified of standing in the wrong light or checking up on my makeup between every class.

I have tried various regimens, amoxicillin, doxycycline, various diets, etc, and nothing worked on the deeper issue. Today I still have to deal with regular pimples, but its nothing compared to serious emotionally damaging uncontrollable and unpredicatable cystic acne I started getting around age 19. It been very hard learning to get out of the habit of obsessing over my skin, now that I don't need to worry about it.

Also beware, since I began spironolactone I have noticed that in terms of the few baby pimples I still get now and then, even just a tiny bit of picking will leave me with a scar. Huh.

Hang in there... it is SO worth it! This med is a life savior.
Reviewed on January 21, 2014

I tried everything. Accutane at one point, a bunch of antibiotics, creams, etc. My derm started me on EstroStep BC and Tazorac. Taz works awesome and really tightens pores. However, once I started on Sprio 100 mg, I began to see results. My derm bumped me up to 150 since I was handling the med fine and my skin TOTALLY cleared and no oil EVER. My pores have shrunk and I don't need to wear make up like I used to. I had a horrible initial breakout for 2-3 months and I almost stopped but my derm said to see the full result I needed to wait until the 6 month period. I am at the beginning of the 5th month and looking amazing. I started to see the major improvement the middle of the 4th month. You need to drink a ton of water on this medicine! I know the initial outbreak can be rough (mine was really intense)... however the difference now is night and day. People tell me I have beautiful skin all the time now. Below are helpful research articles I read about the med that are VERY helpful. Be informed of your medicine and be responsible when taking this med. Best of luck!!!

39 years old, finally something that works
Reviewed on October 9, 2013

I have been on Spiro for just under 4 months. Good luck prying this stuff out of my cold, dead hands. I am a 39 year old female and have had acne since the age of 12. My major problems areas have been my jawline, hairline, neck, chest, back, shoulders and arms. I have been able to keep it somewhat under control with topical treatments over the years having the most luck with BP. Last winter something changed though and I started experiencing new kinds of acne, most noticably constant breakouts at my hairline, horrible neck and chest breakouts, and miliary breakouts that I'd never had before. Also my acne was starting to get more cyst-like...definitely went from minor to relatively severe over this time. This also coincided with irregular and painful periods. Suspecting PCOS I was put on 100 mg Spiro a day. I experienced a severe breakout in week two. I won't lie, it sucked. Oh yeah, and my breasts were pretty sore for about a week or so. However I started noticing a few things during the first month: much less oil (I have never gone a single day without showering because my hair and skin were so I can go 2 days without washing my hair...and can skip a day of showering without feeling gross), skin is much smoother, pimples are becoming less severe (instead of cyst-like, they are more normal and quicker to resolve), chest, back, arms and hairline cleared within 1-2 months. I used to have combo skin with oily parts and dry my skin is totally even, and I can quickly apply powder foundation without flakes and oily marks. Third month I was bumped up to 150 mg per day and I would say this is when my neck and jaw made the most improvement. I have not had an active zit for several days (never had I had a day without something somewhere). But all of the sudden my whole life changed. I can wear whatever clothes I want. I had no clothing that didn't cover my shoulders, chest and back completely. I went shopping the other day and was able to try on any thing I saw. Not to sound superficial but for someone like me that is a huge, huge deal. I wore a bathing suit in public for the first time in 2 decades this last Friday.

This is a diuretic so I was thirsty and peeing alot the first few weeks. This passed and I don't notice it now. I have irregular periods but some of this may be due to the PCOS and I will be starting BC soon to try to regulate. Seriously I don't care though....clear skin is soooo worth it. You have to give it time to work though...don't pussy out after the first breakout.

UPDATE: 01/19/14

I just wanted to give an update since it's been a while since my review. After experiencing several months of bi-weekly periods, I went on the birth contol Yasmin. This has totally regulated my periods. I don't get pimples anymore....haven't for 3 months +. I backed down from 150mg per day to 100mg per day a couple weeks ago with no ill effects. The effect this medication has had on my life is nothing short of a miracle for me. Trust me, if you have hormonal acne and you don't give this medication a chance, then your acne must not be that bad. I would have been happy with 50% improvement, but the results have been nothing short of astounding.

Cystic pimples are rare and much less severe
Reviewed on January 19, 2014

I'm a 21 year old female with hormonal acne.

I began taking Spiro in 100 mg doses daily in July 2013, and was upped to 200 mg daily doses in November 2013. It's definitely a medicine that requires patience and will only show results long-term, but I can say that my acne is much less severe. The acne I do get is much smaller and easier to get rid of, and the rare cystic pimple (once every 3 months approx.) goes away much faster.

This medicine IS very dehydrating so it would be best to keep a water bottle available at all times. It can also make mornings a bit more difficult since you NEED to hydrate when you wake up, after sleeping with 8 hours or so with no water.

My period also is a little irregular right now, and I am menstruating twice a month. Spiro will mess with your period in some way, so consult your doctor about it first.

i am clear.
Reviewed on January 11, 2014

While I was recovering from anorexia nervosa, I developed moderate cystic acne on my cheeks and chin. It was painful and humiliating; it only drove my already introverted self to stay in and hide away from the world. I felt like a monster and I avoided looking at myself in the mirror for weeks at a time. About 7 months ago I started taking spironolactone, 100mg…probably the best decision ever. Not gonna lie though, the first three months were hell. I got an initial breakout that was pretty brutal, and I was chronically fatigued for those months. Also, I would get my period twice a month. But all of those negative symptoms dissipated as time went on. I began seeing real results around the 5th month. The key with spiro is BE PATIENT! It took a while but the results are so worth it that i would do it again in a heartbeat. My skin is smooth and completely clear (although i do get a random little spot rarely..gone very fast) and so is this acne on my back! It feels so good to wash my face and just feel…nothing. No pain, just smooth skin, everywhere. The only thing I dislike about this medicine is that it is just a temporary fix. If you stop taking it for a couple of weeks you will break out again.. but if you are desperate for hope and change like I was then I say go for it!

Tips: Drink a lot more water than you're used to. this medication will make you thirsty. If you are drinking alcohol make sure to drink EXTRA water because Spiro is a diuretic and it has the potential to dehydrate you.

Sleep at least 8 hours a day. seriously. You will become a zombie for 3 months if you don't.

Saved my life
Reviewed on January 10, 2014

I've had acne my whole life and when I hit my late 20's it got bad, cystic acne bad. Spironolactone is the ONLY thing that has ever kept me clear long term. I also don't eat junk food or eat wheat, gluten and really any kind of grain which I know helps.

I waited until enough time has passed that I could be 100% totally sure this works before I wrote a review and now I can positively say it works. I've been completely clear for 8 months now. However, I've been on it for about 1.5 years. It took 8 months, almost 9 for it to really work so if you get on it you might have to be patient. But once you get clear all the waiting is worth it and you won't care, you'll just be happy it worked. I'm so glad I tried this before accutane. Highly recommend it. I take 150mg/day, but originally started out at 75mg and after crying in my Dr's office about my skin, I got her to up my scrip to 150mg. I probably wasn't on the full dose of 150mg until about 3 months in.

Spiro! the only thing that's worked!
Reviewed on December 19, 2013

I got painful cystic acne in my late 20's spent a year or two trying a variety of topical prescription medications as well as antibiotics. I was at my breaking point when my dermatologist suggested I take 50mg of spironolactone daily. I wasn't getting results so without consulting him I increased to 100mg daily. Changed my life! I went from a face Full of painful cycstic acne to currently averaging 2-4 blemishes a month. I have thus told my doctor I'm taking 100 mg daily he said that's fine but don't increase the dose anymore. If you are a women over 25 I Highly recommend you give it a try.

Want to gain weight and not clear up your acne? Take this!
Reviewed on December 13, 2013

Did not have any effect on acne, caused extreme dryness/thirst, low blood pressure, and weight gain. Avoid, avoid!

by Guandi on 12/27/2013 17:06
How long were you taking it and what was causing the weight gain? Did it make you hungry?
by DC-girl on 01/10/2014 04:52
You have to give Spiro 7-9 months to work, that's how long it took for me, but it DOES work, it's awesome stuff. You also have to be taking enough. I take 150mg/day. which is higher than they usually start you out at.
by Ann B. on 01/20/2014 07:46
I would sure hate for somebody to not try spiro just based on this review. For spiro to work, the acne does need to be hormonal and/or due to polycystic ovaries....if your acne is due to some other cause, then it may not work for you. It also requires TIME!!!!! I cannot stress this enough!