Page 2 of Spironolactone reviews

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Active Ingredients:
25 mg, 50 mg or 100 mg of Spironolactone.

Inactive Ingredients:
Calcium sulfate dihydrate, colloidal silicon dioxide, croscarmellose sodium, crospovidone, hypromellose, lactose monohydrate, magnesium stearate, peppermint flavor, polydextrose, polyethethylene glycol, povidone, pregelatinized (corn) starch, sodium lauryl sulfate, titanium dioxide and triacetin.

Items marked with orange can be irritating and over-drying, especially to acne-prone skin.

The list of ingredients above is provided for informational purposes only. Always check the actual product label in your possession for the most accurate ingredient information due to product changes or upgrades that may not yet be reflected on our web site.

Where to buy is not associated with this product. All proceeds from links go toward maintenance.

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Satisfied Customer
Reviewed on August 19, 2014

I used to have very clear, porcelain-like skin, until my junior year of high school when I started getting minor breakouts. I went to a derm, and she gave me clindamycin lotion and minocycline 50mg 2x Daily. It worked really well and my acne cleared up. Since my acne wasn't THAT bad, I would forget to take a pill here and there and eventually stopped getting refills of my prescriptions. I had occasional acne but nothing extreme. When I went off to college, I had persistent mild-moderate acne that I couldn't get rid of. It started after I began shaving my upper lip, and I thought it was just razor burn/bumps that would go away after a few days but they didn't. In addition to my pimples I had all these little bumps around the sides of my mouth. I didn't make time to go to a derm until the summer after my freshman year of college (this summer). My derm kind of sucks, but once you get referred to once it's hard to go to any others. I made an apt with her and she walked into the room to see me and immediately stated in a grave tone "Oh, that's not good" right when she looked at my face. As if my confidence was not already shot, having gross uncontrollable bumps all over my face. She said it looked more like perioral dermatis then acne vulgaris and she quickly wrote me a script for minocycline and clindamycin again, the same dosage as before. Out of desperation, I took my pills and applied the lotion exactly as directed, but after the first month I noticed no changes. I came back to my derm after the first month desperate for something different. The day of my apt (before my apt) I was googling about birth controls used to control acne (I've been on cryselle for a few years for PCOS) only to find that my birth control PROMOTES ANDROGENS and therefore is BAD FOR ACNE. I thought all birth controls helped with preventing acne, but I guess I was wrong. Anyways, I went to my derm apt that day and told her about my newfound knowledge about my birth control. She said she doesn't prescribe that type of medicine but suggested I stay on the BCPs I'm currently taking and begin taking Spiro 50mg 1x Daily and continue with the Clindamycin. I didn't want to start taking yet another medication if it wasn't necessary, but I was desperate for clearer skin. I've been taking Spiro for a month now, and my skin is really clearing up. I didn't notice a TERRIBLE initial breakout, I got a few pimples, but nothing worth freaking out over (even though after reading all of these posts, I was REALLY freaking out.) And after like 3.5 weeks, I started getting clearer. It was kind of crazy. It was like one day my skin was producing pimples like normal, and the next day it just wasn't. My skin was actually a little on the dry side this morning. All of my old pimples are healing and all of those pesky little bumps around my mouth are GONE.

As for the side effects, I didn't really notice anything besides the dry mouth and the increase in urine output. That's a small price to pay for the confidence that accompanies clear skin.

I plan to update this as I continue taking spiro.

by truegirl2anna on 08/21/2014 18:43
omggggg!!! THANK YOU FOR POSTING THIS! I almost had the same issues as you! I posted my review above, I feel like you'd relate! I'm just worried because I'm only on 25mg which apparently is enough for me according to my doctor since I have mild acne aka 5-6 ugly pimples on each side of my face, especially on my jaw-line and cheeks. PLEASE do update! BTW I'm 19, turning 20, 5'8 and 125-130ishh? Hoping that wont change by taking this!??!?!?!?!?!?!?!
Reviewed on August 18, 2014

I'm 15 & I've been going to a dermatologist for 3 years. I've tried every wash, every topical cream, even antibiotics to the point where he's said "we've tried everything." I want to take accutane but I have a tendency to

acquire every side effect of every medication I take (the depression is a big factor.)

My doctor just prescribed me Spirolactone & I should start it in a few days. After reading these reviews, I'm so hesitant. I'm dreading the initial breakout, I'm actually crying. I hate looking at myself, I feel so ugly, I've been getting made fun of since my acne started, I can't wear certain clothes because they don't cover it, I'm so self concious I barely wanna make eye contact, i spend so much money on makeup to cover it but it's still awful. The last thing I need is it getting worse. I'm so scared :(

by Anguy1610 on 08/19/2014 03:48
Hi hun, I'm on my second month of Spironolactone and I would have to agree with the rest of these wonderful members who have taken it--I broke out horribly within the first month. Both of my cheeks and chin are absolutely inflamed. My dermatologist actually wants me to go on accutane while I'm still on Spironolactone, but my preference is to remain on one without combining any other medication. I feel the same way as you do-- trust me. I have never been so self-conscious and depressed in my entire life. But patience IS the key. I've changed so many antibiotics and have even undergone the natural/holistic route; nothing has worked. So I've made a vow to myself to stick to one thing for at least 3 months to see how it's working. I'm scared too. The initial breakout has basically traumatized me, but I'm finding strength in all of the posts made here on this website. I'll update you on my journey! Best wishes! Let's be strong together :)
by truegirl2anna on 08/21/2014 18:01
I struggle with mild/moderate acne. I was diagnosed with PCOS, so not only did i have bad skin, i also had extra body hair TMI but seriously. I have been on spironolactone for about 3 and a half weeks, at first my skin was already clearing up, then bam, i had the initial breakout. It can last for only a few days, for some people ircan be a few months. It is just your body getting used to the medication and balancing out hormones. It's basically your body finally gettin' it's stuff together lol. Don't worry, just be patient, as hard as that is for me to even type, it's true. I've done so much research on all of the different experiences people have and ya know what? PATIENCE is the number one thing ya need. Think how long you've waited to have clear skin, just give it 6 months to fully work, and that's nothing! Just wait and try it out, you'll probably look back and wish you started sooner!
Better than anything else out there
Reviewed on August 13, 2014

Six years on Spirano and just quit for the second time in that period. I would break through every so often, but it's more dependable and safe than antibiotics and BCP. BCP is supposed to increase its effectiveness, but there are risks to excess estrogen, most notably weight gain and emotional sensitivity. It's almost worth it for the clear skin and diauretic effects.

Reviewed on August 13, 2014

It does work, but it's not a cure. It's a band aid like most antibiotics. As long as your on the medicine it will work, once you come off of it for a while it will come back if you have severe acne. If you're willing to stay on this medicine for a long period of time then it will benefit you. As for myself I don't like taking medicine for a long time so I'll give it 4 stars for doing it's job.

So thankful to have found this medication
Reviewed on August 12, 2014

I'm a 24 year old female. My acne has always been considered moderate to a dermatologist, but of course to me it felt severe. In the last few years my acne became worse than when I was a teenager. My zits were cystic, more numerous, and relentless. Unfortunately, my skin had a great effect on my attitude and my mood. Whether my day was good or bad was highly dependent on the degree to which I was breaking out. I had tried antibiotics, birth control, topicals like proactive, retin-a (of varying strengths), reducing my dairy consumption, becoming a vegetarian, and much more and with nothing to show. I think the constant nuclear warfare on my face in fact worsened my skin and caused further irritation. My mom emailed me with an epiphany one day. She recalled after her pregnancy with me she was prescribed a water pill to help her with some horrible cystic acne she was experiencing. She said it cleared her up almost immediately. I made an appointment with my doctor shortly after and was prescribed 25mg of spironolactone daily. The doctor was slightly hesitant, and she made sure to run through the list of every other prescription available (all of which I had tried) before agreeing to prescribe me this pill. I began this medication in March and it is August now and I truly could not be more pleased. My skin is not only clear but it is predictable. I don't dread looking in the mirror each morning only to discover 3 new massive zits. My skin is stable. I am not without some occasional small pimples of course, but they are small and infrequent. I'm not embarrassed to be seen without thick layers of foundation and I'm not afraid of humidity or sweating my make-up off. I'm so thankful to have found this medication. I only wish my mom had recalled her experience sooner!

(Note: I do take this in conjunction with birth control. The birth control pill never did the trick for me but it is possible the combination of these two medications are giving me the ultimate effect)

by cleargoal on 08/12/2014 02:32
Hi, thanks for the review. I've recently been prescribed Spironolactone but my dermatologist wasn't hesitant with a 50mg prescription. I'm also a 24 year old female with a very similar acne story. Could you share why yours was? - Cheers
by truegirl2anna on 08/21/2014 18:09
I am 19 and was diagnosed with PCOS. I take provera only for 5 days out of the month to regulate my period, however i am so thankful I stumbled upon your review. I am only on 25mg of spiro, and it felt as if everyone was only having success on 50-100mg. I don't have cystic acne, nor have I ever, I just have breakouts almost all of the time. 5-8 red irritatd pimples, along with oily skin. I would have to caked my make-up on to make it look like I had "normal" skin. So I'm right on the same boat with ya'! I guess I'm just scared because for the first 2 week my skin was already clearing up, and started having a "glowy" look to it, then all of a sudden BAMM! I broke out as if I had just wore make-up for 2 days straight, while eating greasy food before my period (which I had gotten my period a week before so I knew it wasn't PMS pimples) I just hope this is only an "inital breakout" that everyone says happens. Or if I just need to up my dose, then again I don't have anywhere near severe or cystic acne, just ugly pimples all the time on my cheeks and sides of my face.
Finally a perfect treatment!!
Reviewed on June 14, 2013

I've been on spiro for 5 months I have been taking 100 mg daily and am currently still at this dosage. I started spiro three months after completing my accutane course. Unfortunatly I broke out after the accutane. I started the spiro and started to clear up after a month of use. Since then I'm not getting cysts or big pustular acne. I get a couple white heads here and there but the full benefits of spiro can take up to 9 months to show themselves. So I'm looking forward to having clear skin long term!!


I've now been using Spiro daily for 14 months now. Still at the 100mg dose. It's managing to keep my skin nice and breakout free. I can't thank this medication enough. It completely rid me of the paranoia and fear of looking in the mirror in the morning and not knowing what I was going to face. I will admit I get a white head every couple of months. That's nothing to complain about! I do not have any side effects from the medication at all. All my blood results have come back perfectly. I love it!

by Cali04 on 06/17/2013 01:45
Are you using any gel? Or did the Spiro just work for you by itself? Thank you!!
by Like Moonlight on 08/25/2013 07:23
I'm not using a topical no. Just the spiro
Late 20s and finally found a cure with Spiro
Reviewed on July 17, 2014

I have tried everything under the sun, and finally my dermatologist prescribed Spironolactone for me and my face has been clear now for 3-4 months. It took about 2 months before I started noticing a difference, but it was worth it. Additionally, I also started running 3-4 times a week and doing Crossfit 3 times a week along with cutting flour out of my diet for all meals except 2 per week. Perhaps a combo of the Spironolactone, a good exercise regime and eating better was the key, but I am so glad because I have battled skin issues for almost the entire decade of my 20s. Also, it's a good idea to increase your water intake with this drug because it is a diuretic, so I have done really well with that. The more water, the better for your skin. Lastly, I swear by washing your face morning and night with the plain orange liquid neutrogena, applying Olay Regenerist moisturizer in the morning after washing your face, and using neutrogena concealer for small cover-ups and a little bit of the neutrogena powder. Foundation is the devil. Everytime I go back to wearing foundation, I can almost always bet on breaking out. Less is more when it comes to wearing make-up AND keeping your skin clear!

Major Improvement!
Reviewed on July 3, 2014

Hello all!

I have been struggling with moderate face (mainly on my jaw line and cheek bone area), back, and chest acne since I was 14 years old. I have tried multiple topical treatments, as well as oral antibiotics for my acne. Initially, each product seemed to work great .... until it didn't anymore! My acne has been a problem on and off for the past 10 years, as I am now almost 24. A total struggle! Finally I found a provider who actually wanted to help me clear up my acne. And of course I love her, as she is a physician assistant like myself. We decided to go with Spiro, because we both felt that my acne was mainly hormonal. Initially I was on 25 mg 2x / day. I had no side effects at all. Bacne - GONE. You would never know I had an issue. Face and chest not so much. After 3 months I went for my f/u appointment and she increased me to 50mg 2x / day and we added Retin A Micro (I'm using the generic form which is just tretinoin gel). In 2 weeks I've seen MAJOR improvement in my face and chest. I currently have no active breakouts, just some left over hyper pigmentation (which I am eager to get rid of!) I only apply the Retin A at night to affected areas (if I put it all over my face it gets to dry). I also use St. Ives anti blemish exfoliating wash every night (I swear by it).

HOWEVER....ladies pay attention to what makeup you are using. Once I switched to MakeUP Forever (you can get their products at Sephora) I have also noticed a HUGE difference compared to drug store brands. It's worth the extra couple of bucks and it lasts longer! I also wash my makeup brushes every other week...and I apply foundation with CLEAN fingers only.

DRINK DRINK DRINK lots of WATER! Not only is it necessary while taking Spiro, but it is just good for your skin in general.

All in all, Spiro gets an A+++ in my book.

I LOVE Spironolactone for my acne
Reviewed on July 2, 2014

I'm a female and I was on Accutane 2 times, then Ortho Tri-Cyclen and then Spironolactone for my acne. I decided it was finally time to share my story. You can see pictures too. My share is a bit long, but I wanted to be comprehensive. All or nothing. I pasted it in the blog:

Reviewed on June 30, 2014

3 months ago my doctor put me on a 50mg dosage.. to say the least it did not help with my acne at all it was all around my jaw line and forehead. about a month ago he bumped my dosage to 100mg a day (2 pills) and ever since then my acne got 100xs worse!! Its all over my cheeks and my neck. Does it get worse before it gets better? Should I wait it out? has this happened to anyone ? any info would be great

by Ann B. on 08/10/2014 15:35
YES....It does get worse before it gets better. I think your doc did the right thing bumping your dose up. I started on 100mg and had the initial breakout about 1-2 weeks after starting, and let's not lie, it was a MAJOR breakout. Please be patient and don't get down. I would say it was very gradual improvement over the first 2-3 months....months 4 & 5 were where I saw the most amazing results. HANG IN THERE!