These pills work amazingly well for ME. After 5 years of having moderate acne with large, painful bumps that left bad scars, I had zero self-confidence. It got so bad that some days I wouldn't go out in public. I was trying every cleanser I could find, going on antibiotic pills and creams, using Differin and Retin-A, trying different birth controls, cutting dairy products out of my diet completely, and going to many other difficult and sometimes extreme measures in order to clear my skin, but nothing worked. But after reading a lot of great reviews about ortho tri-cyclen, I decided I would make one last attempt at clearing my skin. I loved it right away! I barely had any PMS symptoms, and my skin was instantly less oily and every morning when I looked in the mirror I had fewer pimples! For the first few months I still broke out around that lovely time of the month, but I can say after 5 months of using ortho tri-cyclen that my skin is TOTALLY CLEAR! I never thought I would be able to say I don't have acne, but it feels so amazing to be confident going out in public, even without makeup! So, I guess the bottom line is that after much trial and error, I found the cure for MY acne. Everyone's skin reacts differently to treatments, which is why acne is so hard to get rid of. All I do is live a clean lifestyle and take these pills every day, and for MY skin, that's all I need! I drink about a gallon of water every day, ALWAYS wash my face twice a day (using Clean and Clear Continuous Control cleanser), keep bacteria off my face (use clean makeup brushes, sleep on clean pillow cases, etc.), and take these pills every night. It truly is an amazing feeling to have clear skin! If you haven't found what works for you yet, I know exactly how you feel, and I would encourage you to start by drinking a lot of water, keeping your face clean, and living an overall healthy lifestyle. From there, I would definitely recommend trying ortho, just remember to be patient! Good luck :