It may sound like blasphemy to say it on this site but over the now 13 years that I have had acne, I realize that just using water on my face has worked the best for me. Proactive, The Regimen, every retinoid, every antibiotic, etc.
I have used the regimen about 3 different times (each lasting over a year) and quit each time despite it helping a bit. I always had a feeling that the cleansing portion was hurting my results (my face was barely able to move after I would wash my face) but was told constantly it was the BP causing the dry and uncomfortable skin. I also had developed eczema and red patches on my face and it always itched.
6 months ago, I decided to give the regimen a final shot but without using a cleanser as I always hated that part. I just run water over it before applying BP. I can now use 2 pumps of BP, or more if I want, and my results have been amazing. I get a small pimple every 2 weeks with zero dryness or irritation despite a ton of BP.
Just something to think about if you are prone to irritation as I have personally found out that cleansing has only been harmful to my skin and played no part in decreased breakouts. Also my moisturizer of choice is Cerave Moisturizing Lotion. I mix it with some jojoba oil and it works perfect.