I totally agree. Topicals are a wasted of time and money. I have tried every topical and none of them reduce oil. I know it perfectly, because I have a master degree in acne after suffering from 13 years old to 43 years (actually).
The only thing that improve your skin, and decrease oil is ingredients AntiDht.
I am 43 years old, female, suffering from cystic acne since I was 13 and not cured but 80% cured. The only advice I can give you after so many years of this horror desease is not wasting your time with topicals, as I did.
The only thing that improve my skin (but not cured) was the ingredients antiDht as Diane35, zinc 50 mg, pumpkin seed oil 50 mg, and recently I have started taking SawPalmetto. I also think tha Spiro has been a great solution for some people, but I have low blood pressure and I fainted the first week with just 50 mg of Spiro. Check out Green Gables posts about Spiro, they are awesome.
Thank you Laitholiel for sharing your experience about saw palmetto, it`s very useful for me.
I am currently taking Diane35, but it,not enough for me, and I think I have excess of androgen, and 2 miligrames of ciproterone acetato is not enough. That,s the reason I am actually taking zinc 50 mg + pumpkin seed oil 50 mg + 160 mg of saw palmetto, but I have been taking it just for a month and it´s very soon to say something.
I did´t understand well. So, you say you are actually taking 320 mg or 600 mg a day? ( english is not my first language). And in case you have decreased your dosage, have you had better results? I am asking because my skin is even now so oily.
I am also interesting to know the effects of vitamine B5 in testosterone. I thought it was vitamine b6 and not vitamine B5 that has relation with testosterone, please, Green Gable, tell us your experience with B5. And there is a theory about the conexion between a deficit in coenzyme A ( vitamine B5) and Acne ( from a chinese doctor Dr.Lee I think).
I have read that vitamine B6 reduces prolactin, and a reduction in prolactin levels avoid the conversion of testosterone to DHT.