It's jsmithson, back with yet another interesting topic! I came across a new science study about a Korean light therapy device in the British Journal of Dermatology:
"The clinical and histological effect of home-use, combination blue-red LED phototherapy for mild to moderate acne vulgaris in Korean patients: a double blind, randomized controlled trial"
You gotta pay to read it so I'll summarise it for you here. They tested a device from Ceragem Medisys called the MP 200. It's a combination blue (420nm) and red (660nm) light device that you use at home. You irradiate yourself for 5 minutes twice a day. After 12 weeks they found some very interesting results:
- Acne lesion counts down by average 77% and 54% (inflammatory and non-inflammatory respectively) in the treatment group. No change in the control group.
- Average 25% reduction in the area of the sebaceous gland (I assume this is a cross sectional area) in the treatment group. No change in the control group.
- Molecular markers for inflammation and sebum production (SREBP-1, IGF-1R, TLR-2, IL-1a, IL-8) were down in the treatment group. No change in the control group.
- Virtually no side effects (10% of treatment group reported 24 hours of mild dryness at one point in the study!)
- The study compares the treatment in effectiveness to topical retinoids and antibiotics but with less side effects.
- The blue light kills p.acnes via a PDT reaction. Since p.acnes stimulates oil production and inflammation, a reduction in oil production and inflammation is seen after treament.
- The red light has an anti inflammatory effect and accelerates wound healing.
This study is good for acne but also for us oily folk. I haven't found anywhere that sells the device so I don't know how much it costs. If it's not really expensive (it's just a bunch of LED's after all) I'll give it a shot!
jsmithsonMember Since 26 Nov 2006
Offline Last Active Sep 12 2013 10:13 PM
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Currently trying this at home: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283851/
I'm watching Dermira Lemuteporfin: http://www.dermira.com/tech-Lemuteporfin.html
And Cosmo cb-03-01: http://www.cosmopharmaceuticals.com/activities/pipeline/cb.aspx