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jsmithson

Member Since 26 Nov 2006
Offline Last Active Sep 12 2013 10:13 PM

Topics I've Started

A New Light Therapy Device For Oil / Acne Improvement

05 January 2013 - 10:47 PM

Yo!

It's jsmithson, back with yet another interesting topic! I came across a new science study about a Korean light therapy device in the British Journal of Dermatology:

"The clinical and histological effect of home-use, combination blue-red LED phototherapy for mild to moderate acne vulgaris in Korean patients: a double blind, randomized controlled trial"

You gotta pay to read it so I'll summarise it for you here. They tested a device from Ceragem Medisys called the MP 200. It's a combination blue (420nm) and red (660nm) light device that you use at home. You irradiate yourself for 5 minutes twice a day. After 12 weeks they found some very interesting results:

- Acne lesion counts down by average 77% and 54% (inflammatory and non-inflammatory respectively) in the treatment group. No change in the control group.
- Average 25% reduction in the area of the sebaceous gland (I assume this is a cross sectional area) in the treatment group. No change in the control group.
- Molecular markers for inflammation and sebum production (SREBP-1, IGF-1R, TLR-2, IL-1a, IL-8) were down in the treatment group. No change in the control group.
- Virtually no side effects (10% of treatment group reported 24 hours of mild dryness at one point in the study!)
- The study compares the treatment in effectiveness to topical retinoids and antibiotics but with less side effects.
- The blue light kills p.acnes via a PDT reaction. Since p.acnes stimulates oil production and inflammation, a reduction in oil production and inflammation is seen after treament.
- The red light has an anti inflammatory effect and accelerates wound healing.

This study is good for acne but also for us oily folk. I haven't found anywhere that sells the device so I don't know how much it costs. If it's not really expensive (it's just a bunch of LED's after all) I'll give it a shot!

Oily Skin Clinical Trial - Here's Your Chance If You Live In Usa!

08 September 2012 - 09:11 AM

http://www.cosmophar...ipeline/cb.aspx

I've been keeping an eye on this product for some time now. It's a topical oil reducer. If you live in USA you have a chance to get into the clinical trial which have recently started:

http://clinicaltrial...cb-03-01&rank=1

Of course I live in Melbourne, Australia so it's off limits for me!

Oily Skin - Try Reducing The Ambient Temperature

08 September 2012 - 09:03 AM

This is something that has taken me a long time for me to realise: the ambient temperature affects my skin's oil production.

I've noticed that when I'm in a warm / hot environment for a long period (1 hour or longer), my skin produces more oil than normal. Conversely when I'm in a cold environment my skin produces less oil than normal.

This is obvious in 2 respects: the first is that I can actually see the change in oil on the skin surface after a period of time; the second is that my skin is in much better condition acne wise when I am in a cold environment for a prolonged period of time.

So of course I've recently been turning my house's heater down / off...

A Quick Survey For Those With Oily Skin

13 April 2012 - 08:17 AM

Hi folks!

A quick survey:

1. How often do you eat foods that contain large amounts of carbohydrate such as candy/confectionery, soft drinks, fruit, fruit juice, rice/pasta/bread/grains, breakfast cereal, etc?

2. How often do you eat dairy or dairy derived foods like milk, cheese, whey protein, etc?

3. How often do you work out at the gym? (resistance training)

I can answer yes in a big way to all 3 questions: I did all of those things for many years. From the stuff I've read there is a correlation between those activities and oily skin.

It would be interesting to see if the folks on this forum do the same!

New Product Being Tested Specifically For Sebum Reduction

27 March 2012 - 03:18 PM

Ok so I found something good during my usual trawl of clinicaltrials.gov.

There's a new pharma company called 'Dermira' which seems to be focusing on sebum reducing agents. Of course their target market is acne because it's such a huge market but it can benefit us oilies too!

Their most advanced agent is called 'lemuteporfin' which when used with light therapy reduces the size of sebaceous glands. Unfortunately it's not a permanent solution - you'd have to keep going back to keep your oil down - but it sounds promising.

Here's their web site:

http://dermira.com/t...muteporfin.html

And here's the clinical trial:

http://clinicaltrial...01490736&rank=1