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discomfortzone

Member Since 06 Sep 2013
Offline Last Active Sep 11 2014 05:54 PM

Posts I've Made

In Topic: Vitamin B5 Hairloss- Cured (Pictures)

11 September 2014 - 07:23 AM

@churchill

Indeed, credit goes to itsoveriknowiknow. Sorry about that, I copied & pasted your name by mistake.

Actually, I think everyone on this thread deserves a pat on the back - this entire ordeal has been a real bear.

As far as mitigating hyperactive adrenals, it’s a pretty complicated feat. You can listen to this discussion on youtube to get an idea of what it might entail: youtu.be/SM9vDjCuhvQ

I suggest that we each make a list of all the symptoms we’ve experienced. Include everything that seemed off: for example, insomnia, the periodic tingling sensation in the feet, the hardening of the sebum, itchy scalp, dry eyes, an increase in androgenicity (DHT is a powerful androgen that can cause back/shoulder hair), etc. This way we can compile a list of symptoms of this disorder, making it easier to troubleshoot and qualify/quantify progress.

I would strongly suggest that we do this before reading other people’s accounts, so as to avoid being influenced by what the others describe. We can compare our notes afterward and create a composite list.


In Topic: Vitamin B5 Hairloss- Cured (Pictures)

10 September 2014 - 03:14 PM

Hi all,

I've been keeping an eye on this discussion since my last posting back in October of last year. It has been very informative (well, for the most part:), so thanks to everyone who has contributed to this thread. I guess the bad news is that we're all still shedding, but the upside is that, perhaps, in collaboration we might find a way to remedy our common, self-inflicted snafu. Here is my  $0.02.

Over the past year, I have tried to tackle this problem from multiple angles via vitamin/mineral/antioxidant supplementation (vitamins B1, B2, B3, B6, B7, B12, D, E, magnesium, zinc, curmcumin, NAC); topical treatments (ketoconazole, minoxidil, corticosteroids, azelaic acid, essential oils); the use of adaptogens and adrenal support supplements (ashwagandha, valerian root, Relora, rhodiola, Seriphos); as well as anti-androgenic supplements (Saw Palmetto, Nettle Root Extract). Unfortunately, thus far nothing has worked very well – I still have scalp irritation/inflammation and my hair loss continues. If I had to estimate, I’m down to about 30-40% of the follicles in the anagen (active) phase.

I can elaborate on what I’ve done and the rationale for why I’d chosen any particular approach if anyone wants to know.

My background is in chemistry and pharma, so knowing the jargon and the basics of the healthcare reimbursement system I was able to convince my pcp to run a lot of tests for me, which he had reluctantly agreed to do. I have to double check, but I think that all of my vitamin/mineral panels came back normal, while some of my hormones were out of whack.

@Elessarx

I had my cortisol tested three times using two different methodologies. The blood cortisol test (sample drawn in the morning when the cortisol level is supposed to peak) came back normal while both of the 24h urine tests (urine collected over 24 hours and tested for the total amount of cortisol) showed my cortisol levels elevated (almost 4 times above normal). Our cortisol levels are supposed to follow the circadian rhythm – spike in the morning and diminish towards the evening. Apparently, my adrenals keep secreting cortisol throughout the day (hence the issues with sleep),  This would also explain the discrepancy in the cortisol test results.  As I’ve mentioned a while ago, I suspect that the B5 megadosing has thrown our HPA axis out of kilter, putting our adrenals in hyperdrive. If not corrected, this will eventually lead to adrenal fatigue, which will, in turn, affect the thyroid function.

@Hermetic

That is some excellent news, man. Hopefully, your results are generalizable and can be reproduced in others.

@churchill

I really like your idea of trying each of the components of Hermetic’s regimen to see which one did it for him, or if it was a combination of some or all of them. I suspect the glandulars are to “blame” though.

I could also take part in this little experiment – take, for example, colostrums for 6 weeks and report the results. If other people are willing to participate, maybe we can assign and keep track of who is trying what. We should also come up with a list of symptoms and a qualitative way to measure outcomes (e.g. variable A ‘scalp irritation’ ranging from 0 to 5, with 0 being ‘no irritation’ and 5… well, you get the idea). Let me know what you guys think.


In Topic: Vitamin B5 Hairloss- Cured (Pictures)

23 October 2013 - 10:15 PM

So has anybody heard about kerastase densifique? It's suppost to be the latest best thing for hairloss and claims to reawaken hair follicles. It also says you can regrow upto 4000 new hairs in 3 months.

Nice find, man. I'm curious as to how effective it really is.


In Topic: Vitamin B5 Hairloss- Cured (Pictures)

19 October 2013 - 06:34 PM

I got back the results of my latest blood work – vitamins B2, B6, B12, D as well as Copper, Iron, Lead, Mercury and Zinc – all came back normal. So, there is no deficiency/excess of any of these.

In the meantime, I managed to slow down the shedding. What did the trick in my case is Magnesium + Chelated Zinc  (400/15 mg twice a day) and some adaptogens along with calming herbal supplements to help keep cortisol in check. It seems to be working, so I’m a bit more optimistic now than I was a month ago. 

As a side note, my visits to the gym have become less of a drag, as I definitely feel more energetic.


In Topic: Vitamin B5 Hairloss- Cured (Pictures)

28 September 2013 - 11:46 AM

Dhea is produced by the adrenal glands which again goes back to my theory that the adrenals are playing a massive part in the hairloss. The only reasons that the adrenals will produce more dhea than normal is due to, toxins in the body, Pollution, stress, And medications. We could be getting somewhere here.

High DHEA levels are often associated with high cortisol, which in turn suggests hyperactive adrenals (out of balance HPA axis). As I have alluded to in my first post, megadosing on b5 seems to affect the HPA axis and cause overproduction of adrenal hormones (cortisol in particular), until the adrenals are exhausted.

The question is whether high cortisol is what's causing the hair loss or if there are other factors (e.g. Cu/Zn/Mg deficiencies) that are more directly responsible for this symptom. I had an episode of rapid hair shedding back in December (2-3 months after I'd stopped supplementing with b5) and back then taking remedies for adrenal fatigue seemed to have helped quite a bit. There is a very interesting talk on this topic (youtu.be/SM9vDjCuhvQ).