the swelling of the brain is supposed to be a very rare side effect according to my derm. I've been on Accutane(Myorisan) for 7 months and I got maybe one or two headaches when I started Accutane. My advice is to invest in some cortibalm and good moisturizer because your lips will be REALLY dry. I wear contacts and my eyes have been dry on and off and I actually ended up getting a corneal ulcer. I think it was a combination of me stupidly falling asleep in my contacts one night and my dry eyes. my eye dr. told me to use systane drops to help keep my eyes moisturized. As long as you're armed with the right tools I think you'll be fine.
I'm also 28 years old btw