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Quetzlcoatl

Member Since 04 Mar 2013
Offline Last Active Today, 01:36 AM

#3461111 Going Off Accutane Early? Scared Of Side Effects.

Posted by Quetzlcoatl on Today, 01:25 AM

It's a risk you have to consider. Permanent side effects are very, very rare, unless you go into accutane with nutritional imbalances (like low vitamin D). No one can tell you that the dry eyes will 100% not be permanent. But from all of the anecdotes I've seen, it basically always reverts within a month after being off treatment. So will the red skin.

 

If I were in your position, I would push through. The length of treatment is more important than the dosage, and if you were going to get any permanent side effects, you would have gotten them by now. One more month, hell, three more months, are very unlikely to cause any more harm.




#3454408 I Got Tested For A Food Intolerance Test... Here's What I Found Out

Posted by Quetzlcoatl on 03 October 2014 - 02:00 PM

Candida is rarely the issue, even though many think it is. The issue is general dysbiosis, caused by an imbalance in usually bacteria. A probiotic rich diet of whole foods will still help this condition, however; but avoiding sugars is largely unnecessary if the sugars are coming from whole food sources in reasonable amounts.


#3454406 Need Help With Finding The Problem For Cystic Acne!

Posted by Quetzlcoatl on 03 October 2014 - 01:56 PM

Avoid all wheat products. Pasta, bread, cereal, pancakes, cookies, etc. Cystic acne is very often caused by a food sensitivity. Yours could be wheat. It isn't easy, I'll warn you. Wheat flour is often added to things like soup and sauces.


#3453866 Is What Im Eating Fine? Please Comment :d

Posted by Quetzlcoatl on 29 September 2014 - 07:43 PM

There are wheat-free breads available. I like to enjoy a millet-zucchini bread when I'm in the mood for a sandwich or melt. It tastes like normal bread, but has a thicker consistency, kind of like rye.

 

It would be better, though, if you didn't eat a sandwich every day. There are lots of delicious cuts of meat that you can combine with herbs and sauces to make amazing food. I would also recommend eating eggs at least once a week.




#3453860 Is What Im Eating Fine? Please Comment :d

Posted by Quetzlcoatl on 29 September 2014 - 07:30 PM

I would get rid of the wheat - the ciabatta and the frosted mini wheats. Other than that, your a bit heavy on the carbs. Consider replacing some of the fruit, particularly the melon, with dark leafy greens.


#3452538 Sebum Quality

Posted by Quetzlcoatl on 18 September 2014 - 08:39 AM

Yes, which is what I said




#3451854 Understand & Cure Acne- The Skin Is Used For Excretion!

Posted by Quetzlcoatl on 13 September 2014 - 08:01 AM

This is mostly voodoo. There is a lot of science behind and, and it's becoming apparent that the cause is almost always immune dysfunction in some form.

 

what if my blood is great and i have no inflammation and have good immunity?

 

Then you don't have acne




#3450742 Y Does It Take 666 Million Years To Fade Redmarks ?

Posted by Quetzlcoatl on 05 September 2014 - 05:22 PM

Diet looks great.  I'm still on accutane so the reddishness is still here, but I have no doubt it will go away. I do basically paleo but I consume a lot of fermented dairy. I recommend yogurt as it is highly insulinogenic and will increase the turnover rate of your skin.

Vitamin D can potentially help as well, as can mild sun damage/tanning.

Many vitamins take ages to accumulate (like vitamin D), so keep going strong with the diet and you may see improvement with time.


#3450051 Age Blocker

Posted by Quetzlcoatl on 01 September 2014 - 10:49 AM

So I looked into this a little bit and I think it would be worth it to clarify what benfotiamine actually does.

 

Benfotiamine is a synthetic relative of thiamine. It's been modified to be more lipophilic, which allows for greater biodistribution in tissues. Thiamine, on the other hand, is entirely water soluble, which means that overdosing on it will not really lead to much of a therapeutic benefit as it will be cleared from the blood very quickly. This is the only difference between the two compounds; once thiamine/benfotiamine is inside the cell, the mechanism of action is the same.

 

The mechanism of action is basically increasing sugar metabolism, which raises the threshold for glucose toxicity (glucose toxicity is the state in which the glucose concentration of a media/cell is high enough for proteins to become randomly glycosylated without the need for enzymes. Glucose toxicity directly results in the formation of AGEs).

 

What does this mean? It means that if you are on benfotiamine, it could allow you to eat more sugar without experiencing the negative effects. However, it also means that benfotiamine will not remove AGEs that are already formed. There is no known compound that is able to cleave AGEs at any therapeutic level, but a lot of research is currently being done in this area.

 

That being said, the body naturally metabolizes and excretes AGEs over time. If one were to take benfotiamine for a long period of time to limit the formation of new AGEs, eventually one might see a decrease in total tissue AGEs. This does carry an unknown risk with it, though, as benfotiamine is not thiamine, and could cause unforeseen complications when taken for an extended period of time. This is my conjecture, and I have no evidence for negative side effects, but I think it's worth it to caution against the unknown.

 

A small final point I would have is that using benfotiamine as an excuse to consume extra sugars would result in no net benefit. If one were to aim to reduce their tissue AGEs, they would need to reduce their sugar intake/glycemic load of foods and take benfotiamine at the same time.




#3449249 1500 Negative Posts About Accutane

Posted by Quetzlcoatl on 27 August 2014 - 12:01 PM

Side effects arise and become permanent for a few reasons. If you have a pre-existing autoimmune condition or a family history of such, your risk is probably much higher. If you have mutations in the pathway that metabolizes the drug, your risk is much higher. If you have poor nutrition, your risk is much higher.

Preexisting conditions and family history are easy to decipher. Nutrition is a bit harder, but it can be improved and then excluded as a risk factor. Genetics are the most difficult to deal with, but are also the rarest.

It's important to not that the incidence of side effects is not cumulative. Certain people are at risk for many side effects, whole others are at risk for very few. You need to with that risk for yourself; for most people, it works out, and most people don't give a single damn about recognizing any of the things I listed.


#3447787 Overdosing On Vitamin A, Good Idea Or Nah

Posted by Quetzlcoatl on 18 August 2014 - 07:15 AM

The rate limiting step is the enzyme that converts vitamin A into its derivatives. Overdosing on A will simply allow the vitamin to accumulate in your tissues and possibly lead to some unwanted side effects. Accutane gets around the enzyme issue by being a downstream non rate-limiting metabolite.

There is no such thing as accutane without the side effects.


#3444706 If Acne Was Caused By Diet Why Would It Only Start At Puberty?

Posted by Quetzlcoatl on 31 July 2014 - 07:52 PM

It's more than diet, though. It's also environment, immune system development, and epigenetic inheritance. I think one should be careful of suggesting a single causal factor for the myriad types of acne.




#3444419 Acne Doesn't Signal Illness

Posted by Quetzlcoatl on 30 July 2014 - 04:10 PM

Acne can certainly be an indicator of illness. Chloracne, for example. But even normal acne is present for a reason. At the simplest baseline, having acne means that something is not functioning as it should. In most cases, it's immune system related (though the causes of immune dysfunction are many). Does this mean we have an illness or a flaw? Certainly at least the latter. Can it be fixed? Probably. Is it in our genes? Ultimately, everything is.


#3443843 If Acne Was Caused By Diet Why Would It Only Start At Puberty?

Posted by Quetzlcoatl on 27 July 2014 - 07:12 PM

These are studies not facts. Not every study is right actually many are absurdly flawed (vaccines cause autism ect.). 

 

I think what you're trying to say is that acne is really an immune system issue. If that were the case wouldn't that spread over into other aspects of the immune system? Wouldn't acne patients be sick all the time if they were so immune impaired. 

 

I have had acne since I was 12 which warranted Accutane at 17 and have always had a normal immune system. Even as a now ventilator dependent quadriplegic I rarely ever get sick with UTI's or upper respitory infections. Why is that? 

 

Nothing is really a fact, but we have occam's razor for that. Acne has nothing to do with having a 'good' or 'bad' immune system. It has to do with having parts of your immune system dysregulated. And yes, sometimes you will see bleedover effects - people with acne are more likely to be diagnosed with celiac disease, IBD, and dandruff, for example. These same people might have perfectly aligned immune responses to unrelated threats - maybe they have shitty skin, but never catch a cold. Is their immune system good or bad? Neither, really. They just never learned to tolerate a particular microbe that lives on their skin because somewhere along the line, something interfered with the development of a normal immune response to that one microbe.




#3443833 If Acne Was Caused By Diet Why Would It Only Start At Puberty?

Posted by Quetzlcoatl on 27 July 2014 - 06:46 PM


 

.. Also if acne was an immunological condition like some of you are saying why don't they just treat it with steroids? They don't, because it's not. 

 

no derm considers acne an "inflammatory disease" it's considered hormonal and tends to be hereditary. 

 

 

Meh I tried. Believe whatever you want. 

 

You could try reading this article, since I know you will not take my word for it: http://www.medscape....warticle/448506

 

Dermatologists today were educated with principles decades now outdated. Recent research shows that acne is an outcome of immune dysfunction:

 

Isotretinoin normalizes TLR2-mediated immune response: http://www.nature.co...id2012111a.html

 

Correlation between certain immune factors and acne severity: http://eng.med.wanfa...e=zhpf201102017

 

Microcomedogenesis driven by immune factors: http://europepmc.org...ct/MED/23986176

 

 

The information our medical practitioners have is from time to time outdated.