Jump to content

MatthiasINcity

Member Since 02 Oct 2012
Offline Last Active Jan 16 2013 04:30 AM

Posts I've Made

In Topic: Scarless Healing

30 December 2012 - 06:06 AM

Well and don't forget about the use of EPO for woundhealing:

http://www.sumobrain...2012031778.html

Although you might be skeptic as the headline says "scar-free healing" and the first paragraph in english says "significantly less scarring", in the german text it clearly says this method achieved scarfree healing in second degree scalding injuries and improved the healing of third degree scalding injuries.

I hope they test this method in full thickness excisions, because they mention that additional dermal stemcells in combination with the use of EPO improve the woundhealing effect of the EPO but no example where this has been done is included in the patent.

Also, I wonder if this could work in combination with a rapidly degradable hydrogel.

In Topic: Scarless Healing

29 December 2012 - 09:06 AM

@ Chuckstonchew:
Sorry for the late reply. I'm afraid the EPO related patent doesn't mention this method beeing used on a full thickness excision.

Also in one of the examples, where this has been used on a child with deep second-degree and third-degree scalding injuries, only the second-degree spots healed without scars and the third-degree spots only improved.

I still think this is interesting as there are several variations of this method mentioned in the patent. The EPO can be applied by injections or via hydrogel. For cases where a lot of the original tissue is lost, the patients own stemcells can be added into the hydrogel.

I just wonder if additional EPO and dermal stemcells would improve the regenerative capabilities of a rapidly degrading hydrogel.

In Topic: Scarless Healing

18 December 2012 - 04:48 PM

This method has actually been used in humans and brought scarfree regeneration in second-degree scalding injuries and non healing skin ulcers, according to the patent. Right now, this is beeing tested in clinical trials in Germany.

In Topic: Scarless Healing

18 December 2012 - 01:17 PM

Somehow everyone ignored my post, so I'll repost this :D

http://www.ncbi.nlm....pubmed/22419870

Although this only brought complete regeneration in second-degree scalding injuries, I think it's still interesting.

This method of using EPO is based on a german patent that's been postet in this topic.

In Topic: Scarless Healing

13 December 2012 - 04:35 PM

Has this already been postet ?

http://www.ncbi.nlm....pubmed/22419870

I think it sounds interesting, although it only achieved complete regeneration in second-degree scalding injuries.