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Hector12345

Member Since 17 Nov 2011
Offline Last Active Apr 15 2014 07:37 AM

Posts I've Made

In Topic: Omnivium's Low Dose Accutane Log

29 March 2014 - 03:29 PM

Hello.

 

I´m hector and I had the worst acne I´ve ever seen live (Sorry for my bad english i hope you understand what I mean).

I will tell you my isotretinoin story, I´ve been taking that for a long time!:

 

  • 1st time: Legal low dose
    • (2002 - I was 17yo)
    • 20 mg daily for 4 months.
    • Initial break out around the first month.
    • Cleared around the 3rd month.
    • The doctor decided to stop the medication after 4 months.
    • Acne came back after 6 months of retiring the isotretinoin but it was less intense, especially on my face.
  • 2st time: Legal low dose
    • (2007 - I was 23yo)
    • 20 mg daily for 4 months.
    • Initial break out around the first month.
    • Cleared around the 3rd month.
    • The SAME doctor decided to stop the medication AGAIN after 4 months. I told him about the cumulative dose but he said that more time on accutane wont help my acne!
    • Acne came back after 6 - 7 months of retiring the isotretinoin... this time it was less intense too!
  • 3st time: Ilegal low dose (I decided to take the problem in my own hands)
    • (2009 - I was 24yo)
    • 20 mg daily for 5 months.
    • very weak Initial break out around the first month.
    • Cleared around the 2nd month.
    • I decided to stop the medication.
    • Acne came back after 6 - 7 months of retiring the isotretinoin.... less intense but as I told you, I had the worst acne I´ve ever seen. So it was bad anyways...

      I just needed some time to live a normal life. I was contemplating suicide but I didnt do it because of my family, my love to them. (I read that deppression was one of the adverse reactions to isotretinoin.... but by this time ... isotretonoin had already left my body... and I thouth that I was deppressed not because of the traces of isotretinoin on my brain... but because of after all my efforts, ACNE  had came back and crushed all my beautiful dreams and hopes and motivations, I really thought I had a chance to live a normal life, a trip to the beach, walking without a shirt... 

      I decided to go on another course by myself... (even if that would kill me on the long run. I needed some good time on my life. So I exchanged "life quantity: years" for "life quality: happiness")

      On the mean time: I found 4 pills of accutane that i had left. So i started taking one per week just to take them. I was not expecting nothing but BAM!!!!!!! After 4 weeks.... My skin oilness was like a the one of a normal person... and no more break outs... I was schocked! I never thought that isotretinoin could be effective at that dose (one 20mg pill per week???!!! the first time I took isotretinoin It took like 70 pills to kick in!! How can this be possible??!!). I started my google research and found people doing this micro dose approach with excellent results! Even some dermatologist were doing this! 
       
  • 4th Time to now  - ilegal Long term micro dose.
    • (2010 - 25 yo)
    • 20 mg per week
    • No initial breakout
    • Oilness reduction after 5 - 6 weeks
    • No more pimples for about 2 years  :)
    • *Recently I forgot to take my weekly pills for about a month (4 pills) ... and after a while I started breaking out again! Oh I had already forgotten how bad that felt! Brought very bad memories to my mind!  
      I started taking the pills weekly again but I still had one or two cystic pimples on my back every month and since I have dark skin... when they are gone they leave their mark (hiperpigmentation that can last more than 2 years) 
      I was on this problem again. I looked for solutions and decided to double the dosing to 40 mg per week and also include some vitamin D3 (I heard positive results with it, with acne and other chronic diseases so I bought some 10000UI pills)... everything was fine .... but after two months I was breaking out again.... on my back.... just two cysts... but :(
    • My hypothesis:
      • Vitamin A and vitamin D compete with each other. When i add vitamin D, my vitamin A (Isotretinoin) levels went down.
      • Isotretinoin levels stored in my body after the last daily course have already gone down and a little weekly dose like 20mg does not maintain the optimal levels anymore. 

 

I think will take isotretinoin daily again for one month and then try to lower the dosing to 20 per week. I´m still taking vitamin D3 because I think i´m deficient (I found that Isotretinoin can lower your vitamin d3 levels). And since a few days ago... Zinc. I´ll let you know my progress. Ask me anything!!

 

Love you all!

 

Greetings from LatinAmerica!

 

Hector
 


In Topic: Vitamin D Has Cured Me Of Oily Skin And Acne

22 November 2013 - 04:34 PM

It seems like vitamin D3 works like isotretinoin when it comes to 1) the time that It takes in order to start noticing changes 2) the Initial breakout 3) sebum reduction .... I will try this approach!


In Topic: Isotretinoin Low-Ultra Low Dose Long Term Safety

20 November 2013 - 07:27 AM

I´m Héctor

28 years old

Latin American

Dark skin

Previous regimens: After trying everything, ​I went trough two previous regular isotretinoin treatments (4 months taking 20 mg daily) but acne came back after 4 - 5 months.

My actual regimen: Isotretinoin 20 mg per week. (one pill) ... I´ve been doing that for about 2 years. (Without prescription)

Side effects: dry lips but not chopped, less oil on my skin. Sometimes I feel a pain in my lower back... but a lot of my peers do.. so idk if isotretinoin got something to do with it... 


 


In Topic: Isotretinoin Low-Ultra Low Dose Long Term Safety

19 November 2013 - 02:32 PM

Hello. Im Héctor and I´m have been on this regimen for about 2 years. Looking forward to read more posts from you!


In Topic: I Hate My Life :(

09 December 2011 - 02:07 AM

Please guys, stop suffering... im gonna share with you a secret... the acne cure...  just google: Long term micro dose Isotretinoin.... do a lot of research... be aware of the risks(especially for women)... get the pills ... take em and enjoy life. theres a lot of info out there.


look at this:


Low Dose, High Rates of Success

Ultra-low dose isotretinoin is all many acne patients need

San Francisco - Low and ultra-low doses of isotretinoin are an effective therapy for many acne patients. This safer and cheaper solution can even be used continuously.

Gerd Plewig, M.D., believes that the doses of isotretinoin typically used in the United States and Europe are far too high. For many patients, as little as 2.5 mg twice a week, which he describes as "a drop of rain on a dusty road" is adequate.

Dermatologists all over the world already are treating some patients continuously with low doses of isotretinoin, according to Dr. Plewig, director, dermatology and allergy clinic, Ludwig-Maximilian University in Munich.

"When you talk to doctors in this country and other countries of the world, they use 10 mg twice a week or three times a week, which is a low or ultra-low dose. But nobody ever bothered to show and demonstrate that it works," he said. Thus, he and his team performed two clinical trials to assess its efficacy.

Study Spotlights Low Dosing In the first trial, 28 patients with acne conglobata and inflammatory acne took a low dose of isotretinoin: 20 mg/kg, 10 mg/kg, or 0.5 mg/kg body weight daily for six months. In the second study, 11 acne patients took an ultra low dose of isotretinoin: 2.5 mg to 5 mg daily or 2.5 mg twice a week for six months. Both trials involved multiple endpoints, including clinical grading, lesion counts, counts of follicular filaments (believed to be precursors to lesions), bacterial colonization, patients' opinion of seborrhea levels, two objective measurements of sebum levels (Sebutape and Bentonite clay), qualitative assessment of sebum using high power, thin layer chromatography, and biopsies to assess size and configuration of sebaceous glands.

Trials Yield Significant Improvement Results of the first trial in which low doses of isotretinoin were used revealed significant improvements in all parameters tested. Numbers of follicular filaments, and lesions dropped, as did levels of bacteria and sebum. Sebaceous glands shrank, as well.

At the end of the second study, which investigated ultra-low doses of isotretinoin, efficacy was maintained on many of the parameters. There were significant reductions in numbers of active lesions and follicular filaments as well as objective measures of sebum levels. Patients' ratings of seborrhea improved, and levels of P. acnes on the skin diminished.

"The endpoint or the lowest point of a retinoid being effective for the treatment of seborrhea, persistent low grade acne, or maintenance therapy for patients with bad acne probably is around 2.5 mg or 2 mg, or maybe even 1.5 mg," Dr. Plewig said.

The best candidates for low and ultra-low doses isotretinoin therapy, Dr. Plewig said, include patients with severe acne who were controlled with higher doses and require a lower-dose maintenance therapy, individuals whose facial acne has persisted from adolescence into adulthood, and people with sebaceous gland hyperplasia. "Some patients come only because of their oiliness. ... For these patients, I think the low or ultra-low dose is very good, and it's cheap, too," he said.

Severe Patients Still Receive Low Doses Dr. Plewig keeps doses of isotretinoin relatively low in patients with severe acne. "I pretreat patients with severe inflammatory acne with systemic corticosteroids to begin with...about 1 mg/kg body weight for about seven to 14 days, taper it off, and then give an antibiotic, usually an erythromycin, a macrolide," he said. "And then I start with the isotretinoin [0.2 mg/kg to 0.4 mg/kg body weight]. It is so much better. We used to start immediately with isotretinoin or tried antibiotics, but often it takes too long, the patients are miserable, and it is so much better for them because you can have a faster final result, a better final result with cooling down the skin first, then adding your active treatment."

Continuous Use Offers Versatility A great benefit of using lower doses of isotretinoin is that it can be used continuously. There are other important advantages, as well. "In terms of pharmacoeconomics, it is cheaper to use lower doses, it is better tolerated by patients, has fewer side effects, fewer laboratory abnormalities, and of course the patients like it when they have continuous elegant treatment," Dr. Plewig said.

Despite the safer side-effect profile with low-dose isotretinoin, Dr. Plewig emphasized that, at any dose, the drug should still be considered teratogenic and be used with great caution in women of childbearing age.

http://www.dermatolo...il.jsp?id=65528

Prof. Dr. Dr. h. c. G. Plewig
Klinik und Poliklinik ;>für Dermatologie und Allergologie
Ludwig-Maximilians-Universität München
Frauenlobstraße 9 – 11
D-80337 München, Germany
Tel.: +49-89-51 60 60 00
Fax: +49-89-51 60 60 02
E-mail: Gerd.Plewig@;derma.med.uni-muenchen.de


Background: Excessive seborrhea, coarse-pored skin, minimal acne and oily scalp hair comprise a well-known clinical entity. It causes considerable concern, has social impact, and affects the quality of life in some individuals. Some patients seek treatment for seborrhea. No effective topical sebosuppressive medication is available. Oral isotretinoin is the only remedy for men. In women, oral isotretinoin is the most effective remedy, followed by antiandrogens.

Patients and methods: Eleven patients in three groups were treated for 6 months with very low dose isotretinoin. The influence on seborrhea was measured during oral treatment with 5 mg/d, 2.5 mg/d, or 2.5 mg 3× weekly.

Results: Sebum production, measured with Sebutape®, was reduced by up to 64 %. Acne lesions regressed by as much as 84 %. Follicular filaments were reduced by 66 %. Microcomedones were reduced on average up to 86 %. Quantitative bacteriology showed a reduction of Propionibacterium acnes but no increase of Staphylococcus epidermidis. Biopsies revealed a 51 % reduction in sebaceous gland size. With Bentonite™, a reduction of lipids was demonstrated with 2.5 and 5 mg isotretinoin/d but not with 2.5 mg 3× weekly. There was a shift within the lipid fractions: triglycerides dominated, followed by squalenes and free fatty acids.

Conclusions: Good results were achieved in all patients. The small number of patients did not permit a statistical analysis of the three isotretinoin doses studied, but there was a tendency toward better results with the two higher doses.
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