You don't understand what is detoxification. Detoxification is eliminative. You explain me how some methylation issue within the brain (caused by a congested environment btw) will drain the lymph from the kidneys?
Listen, this stuff is not stored in your brain... or your kidney. thats #1. you have to ELIMINATE IT from the body by whatever means necessary(synthetic or otherwise.) The kidney is just one elimination route.... but treating the kidney or lymph nodes wont mobilize the metabolite thats stored in the fat or the liver. you have to deal with the enzymes and genes that deal with the liver detoxification pathways imo.
i think #1 you have to get to a state where the drug metabolite is circulating again... either thru fasting or extreme exercise, and then hit the metabolite with everything to eliminate it. That being all of the active forms of B along with other supportive minerals that deal SPECIFICALLY with your bodies WELL KNOWN methylation processes.
And to say you dont care about the medical studies.... why the @#!%$ am i even arguing with you?????
I don't know where you got the methylation idea from but accutane's removed through glucuronidation, it's bound to a glucuronic acid molecule and removed principally via the kidney's, so again anonyy actually knows what he's talking about. Granted it's also removed in the bile as well but glucuronidation is the process of making a fat soluble compound more water soluble so it can be excreted via that pathway.
Secondly the idea that it's stored in the liver is also wrong, accutane is not retinol, retinol is stored in the liver, retinoic acid is end chain, it doesn't store in the liver, categorically, 100%. One of the things anonyy talks about is drinking kombucha, kombucha is the only known food source of glucuronic acid, it also inhibits the cleaving of glucuronic acid via beta glucuronidase enzymes, these enzymes break the bond between the glucuronic acid molecule and the toxin and force the toxin back into the system, kombucha helps prevent this.
I believe you about it being stored in the body, i have very similar experiences whilst fasting to your own and i'm in complete agreement with you there, others don't believe it, that's fine we can have differing opinions on things, it's not the end of the world. The lymphatic system is very important when dealing with accutane side effects though, you shouldn't poo-poo that idea, the lymph transports fat soluble vitamins to and from the cell, accutane is a fat soluble vitamin so it's transported through the lymph, the lymph removes fat soluble compounds, the lymph has a lot to play in this, anonyy knows.
In fact anonyy deserves more respect than he's being given around here, just because he talks about the bigger picture doesn't mean he's not referencing intuitively the concepts that you are talking about like detoxification pathways, enzymes, etc, he just looks at it more expansively.