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Chico Esposito

Member Since 02 Aug 2011
Offline Last Active Nov 23 2014 11:41 AM

#3457204 Repairing the long-term damage from Accutane

Posted by Chico Esposito on 23 October 2014 - 02:26 PM

Chico youve been on this forum since its inception. By now you would have gained much experience.

Can you tell me what supplements have helped and what you take currently if any?

 

Cheers

 

I don't take any supplements anymore. I've taken them all, i mean you name it and i've taken it, but i don't see things in that way anymore. There was a time were it was "just let me find that one supplement that cures this" that was my approach, i've spent tens of thousands on supplements, it just doesn't work like that. You take something, the power of placebo, you think it's working, then suddenly it stops and you go back to the way it was before.

 

There are broadly two types of people here, ones the flat out react to vitamin A in food and people that don't....i'm in the former. Vitamin A in the form of retinol is poison to my body. The best advice i can give for those people is you must avoid ALL forms of retinol completely. I still eat kale and spinach and high beta carotene foods but egg yolk, butter, milk, cheese, meat, fish - i don't touch it, you can't heal if you don't remove it, you'll just keep adding to the toxicity.

 

Now you might be the type that doesn't react to vitamin A, either way stay away from cod liver oil, just eat what you normally eat. When i was 1-3 years post accutane i could eat whatever i wanted, i didn't react to vitamin A, but the more i ate, the worse it got, now it's 11 years post accutane and i cannot eat it at all, it accumulates.

 

So my advice would be sort out your diet, eat fruits, vegetables, soak nuts and seeds, eat quinoa, lentils, beans etc. Understand nutrition, dry skin brush, yoga, weightlifting, lymph based herbal teas, kidney herbs, echinacea, cleavers,  i drink a tea from Dr Stuart called skin purify it has nettles, red clover, burdock root, dandelion root, drink lots of water. I have a vitamix, i make 1-2 green smoothies a day, i strongly recommend that above juicing for the fiber benefits. Just healthy lifestyle choices really, no isolated supplements, just foods.

 

If you've got dry skin try natural moisturisers like Jojoba oil, grape seed oil, coconut oil, apply argan oil to your hair, explore them. Hope that answers your question timatron, obviously it's not for everyone but that's my honest opinion.




#3456428 Repairing the long-term damage from Accutane

Posted by Chico Esposito on 17 October 2014 - 11:49 AM

Firstly i'm not irrational, the only time i've been irrational on here has been one time to Crank and i've apologised to him for that. Secondly I don't object to other peoples theories, in fact i like reading tryingtohelp and Dubya's posts. I'm interested in the methylation and homeopathic imprint theories, i like reading anonyy's post's and what he has to say on the matter.  

 

I'm just sceptical when someone says "hey i've cured myself by applying grape seed oil once" and then everyone goes out and buys grape seed oil, and then it's "hey i took 15mg of biotin and all my side effects like aching joint's, dry skin, hair loss, it all went away" and then everyone goes out and buys biotin and so on....

 

It's a perpetual loop where it's about buying supplements and not about understanding the root cause. Most of us have hypervitaminosis A side effects, most of us do not disclose the length and severity of side effects we have, so when someone cures something, what have they cured? and what did they have in the first place? 




#3455408 Repairing the long-term damage from Accutane

Posted by Chico Esposito on 10 October 2014 - 01:51 PM

A deficiency of vitamin b12 or folate doesn't cause a reaction to eating foods with any retinol in it, nor does a slow methylation pathway cause aching creaking joints, or exfoliative cheilitis of the lips that crack and bleed at night without vaseline. What we're talking about here is a condition of toxicity not deficiency.

 

Taking B12 or folate is not going to suddenly awaken the liver into purging the toxicity. Nor is taking D3 or K2 going to do anything to the side effects in the short or long term. What Anonyy's talking about is terrain modification of the body, what your talking about is supplement cure alls and you can ask virtually any of us what's the net result of all the supplements we've taken and it'll probably be close to zero. I've taken D3 for nearly 2 years, i've taken vitamin K2 in the form you talk about, i've taken b complex and isolated b12 in really high amounts, did any of them work? no. Did they cost a lot of money? yes.

 

Unless there is a study on 100 people with post accutane side effects ranging from mild to severe in a double blind placebo setting with a cure then i'm not interested because they aren't relevant to us. You have to understand that we are the real 'blank generation' just like Richard Hell sang about. There is no foundation (like ALS) set up in our honour researching a cure for us, you either turn your back on the allopathic community and go it blind or go back to them and get the same results you've always gotten.




#3454793 Repairing the long-term damage from Accutane

Posted by Chico Esposito on 06 October 2014 - 10:42 AM

Durian rider is a complete sociopath / psychopath and thinks everyone that doesn't follow Doug Graham is a quack. The man has about the same amount of intelligence as a plank of wood and bans people from his charlatan site at the first consideration of eating meat, or doing something he doesn't 100% agree with. He charges people hundreds of dollars for a single skype session informing them to eat more banana's, the man is the very definition of charlatan.  He's also been known to send death threats to defectors of his ideology and harassed prominent paleo youtuber’s into getting restraining orders taken out against him, such is the level of abuse. He certainly doesn't deserve to be held up as any sort of truth gauge unless the gauge itself, was a mentalism gauge.

 

Robert Morse sells herbs at exorbitant prices, he doesn't live the lifestyle he preaches, but his information is actually very good. Don't get me wrong, he can be perceived as a charlatan as well and i suppose there is an aspect of that, like with all healers in the sense that he's selling his own product, but i think his intentions are very much noble.

 

About the vitamin A thing, maybe, possible certainly, but then again why would the skin condition completely go away when fasting?

 

As for the ad hominem attacks on your person i do apologise for that, i apologise for discrediting your character, that wasn't called for. i don't however apologise for calling it bs and it does irritate me that this site is used as a 'cannabinoid' research centre, but then again people are probably fed up of my long winded diatribes about accutane, so i can see it both way's. Will you accept my apology Crank?




#3454439 Repairing the long-term damage from Accutane

Posted by Chico Esposito on 03 October 2014 - 07:26 PM

Ha witnessing: 'tryingtohelp2014' vs. 'anonny' brings about a profound sense of deja vu.

I've grown tired of bickering about who's right or wrong, but this thread definitely needs sub-sections so we can debate our hypotheses with like-minded individuals. Rather than concomitantly discussing topics as diverse as methyl regulation as well as eating more apples...

Anyway, now that I've got a functioning internet connection once again I'll post up my 1 month review of RSO in the next couple of days.

Of note, when I'm doing the most exercise I'm feeling at my best. Ahhh the idiosyncrasies, so frustrating in their diversity. 

 

 

Why don't you create a Accutane side effects RSO sub forum, to flog your bs cannabis oil and take your little minion's with you, so the people that actually have problems beyond semi erect penises can debate with each other rather than some Rick Simpson sales man trying to peddle his wears on everyone like it's the gospel truth for 100% of the people.




#3454290 Repairing the long-term damage from Accutane

Posted by Chico Esposito on 02 October 2014 - 01:49 PM

 

 

You don't understand what is detoxification. Detoxification is eliminative. You explain me how some methylation issue within the brain (caused by a congested environment btw) will drain the lymph from the kidneys?

 

Listen, this stuff is not stored in your brain... or your kidney.  thats #1.    you have to ELIMINATE IT from the body by whatever means necessary(synthetic or otherwise.)  The kidney is  just one elimination route.... but treating the kidney or lymph nodes wont mobilize the metabolite thats stored in the fat or the liver.  you have to deal with the enzymes and genes that deal with the liver detoxification pathways imo.

 

i think #1 you have to get to a state where the drug metabolite is circulating again... either thru fasting or extreme exercise, and then hit the metabolite with everything to eliminate it.  That being all of the active forms of B  along with other supportive minerals that deal SPECIFICALLY with your bodies WELL KNOWN methylation processes.

 

 

And to say you dont care about the medical studies.... why the @#!%$ am i even arguing with you?????

 

I don't know where you got the methylation idea from but accutane's removed through glucuronidation, it's bound to a glucuronic acid molecule and removed principally via the kidney's, so again anonyy actually knows what he's talking about. Granted it's also removed in the bile as well but glucuronidation is the process of making a fat soluble compound more water soluble so it can be excreted via that pathway.

 

Secondly the idea that it's stored in the liver is also wrong, accutane is not retinol, retinol is stored in the liver, retinoic acid is end chain, it doesn't store in the liver, categorically, 100%. One of the things anonyy talks about is drinking kombucha, kombucha is the only known food source of glucuronic acid, it also inhibits the cleaving of glucuronic acid via beta glucuronidase enzymes, these enzymes break the bond between the glucuronic acid molecule and the toxin and force the toxin back into the system, kombucha helps prevent this.

 

I believe you about it being stored in the body, i have very similar experiences whilst fasting to your own and i'm in complete agreement with you there, others don't believe it, that's fine we can have differing opinions on things, it's not the end of the world. The lymphatic system is very important when dealing with accutane side effects though, you shouldn't poo-poo that idea, the lymph transports fat soluble vitamins to and from the cell, accutane is a fat soluble vitamin so it's transported through the lymph, the lymph removes fat soluble compounds, the lymph has a lot to play in this, anonyy knows.

 

In fact anonyy deserves more respect than he's being given around here, just because he talks about the bigger picture doesn't mean he's not referencing intuitively the concepts that you are talking about like detoxification pathways, enzymes, etc, he just looks at it more expansively.

 

 

if its not stored in the liver, where is it being stored...because we both know its stillin us...in one form or another.... is it stored in the fat itself...is it constantly being recycled?

 

i read what he said about calcium d glucorinate.... you would have to  take 30,000 mgs to have any effect.  the amount of glucuronic acid in kombucha is negligible 



One of the things Roaccutane (or Accutane or isotretinoin or 13-cis retinoic acid) does is to raise the gene expression of the enzyme glycine N-methyltransferase. This enzyme normally limits the ratio of SAMe to SAH in the methylation cycle. When the activity of this enzyme is increased, the ratio of SAMe to SAH is decreased, and this causes a methylation deficit, so that the many methyltransferase reactions in the body are downregulated. I think this is the connection to ME/CFS. Over the past few years, I have heard from several people who developed ME/CFS after being treated with Accutane. I don't know why this happens to some people, but not to most. I'm aware of one case in which testing indicates that glycine N-methyltransferase has remained upregulated even years after Roaccutane treatment was ended. I don't know why. 

Glycine N-methyltransferase is normally inhibited by 5L-methyl tetrahydrofolate, which is a form of folate used in the methylation treatments. If glycine N-methyltransferase is responsive to it, as it normally is, the methylation treatment should downregulate it. In the case I refer to, this doesn't seem to work, and I don't know why. Perhaps there is a genetic polymorphism in glycine N-methyltransferase in some people that causes it to be unresponsive to methylfolate.

Best regards,

Rich

 

 

 

It's stored in the fat and no it's not constantly recycled, the only time it comes out is during juice fasts or water fasts when you lose body weight really quickly, the fat is being used as energy and it can come out into the circulation, hence the feelings of being on accutane again (dry skin, cracked lips, flushed skin). From my experience it's much better off being left there, detoxifying the lymph is important, if it gets moved it goes to the lymph, remember all cells, even fat cells take in nutrients from the blood and excrete toxins via the lymph.




#3454050 Repairing the long-term damage from Accutane

Posted by Chico Esposito on 30 September 2014 - 08:15 PM

You don't understand what is detoxification. Detoxification is eliminative. You explain me how some methylation issue within the brain (caused by a congested environment btw) will drain the lymph from the kidneys?

 

Listen, this stuff is not stored in your brain... or your kidney.  thats #1.    you have to ELIMINATE IT from the body by whatever means necessary(synthetic or otherwise.)  The kidney is  just one elimination route.... but treating the kidney or lymph nodes wont mobilize the metabolite thats stored in the fat or the liver.  you have to deal with the enzymes and genes that deal with the liver detoxification pathways imo.

 

i think #1 you have to get to a state where the drug metabolite is circulating again... either thru fasting or extreme exercise, and then hit the metabolite with everything to eliminate it.  That being all of the active forms of B  along with other supportive minerals that deal SPECIFICALLY with your bodies WELL KNOWN methylation processes.

 

 

And to say you dont care about the medical studies.... why the @#!%$ am i even arguing with you?????

 

I don't know where you got the methylation idea from but accutane's removed through glucuronidation, it's bound to a glucuronic acid molecule and removed principally via the kidney's, so again anonyy actually knows what he's talking about. Granted it's also removed in the bile as well but glucuronidation is the process of making a fat soluble compound more water soluble so it can be excreted via that pathway.

 

Secondly the idea that it's stored in the liver is also wrong, accutane is not retinol, retinol is stored in the liver, retinoic acid is end chain, it doesn't store in the liver, categorically, 100%. One of the things anonyy talks about is drinking kombucha, kombucha is the only known food source of glucuronic acid, it also inhibits the cleaving of glucuronic acid via beta glucuronidase enzymes, these enzymes break the bond between the glucuronic acid molecule and the toxin and force the toxin back into the system, kombucha helps prevent this.

 

I believe you about it being stored in the body, i have very similar experiences whilst fasting to your own and i'm in complete agreement with you there, others don't believe it, that's fine we can have differing opinions on things, it's not the end of the world. The lymphatic system is very important when dealing with accutane side effects though, you shouldn't poo-poo that idea, the lymph transports fat soluble vitamins to and from the cell, accutane is a fat soluble vitamin so it's transported through the lymph, the lymph removes fat soluble compounds, the lymph has a lot to play in this, anonyy knows.

 

In fact anonyy deserves more respect than he's being given around here, just because he talks about the bigger picture doesn't mean he's not referencing intuitively the concepts that you are talking about like detoxification pathways, enzymes, etc, he just looks at it more expansively.




#3448960 Repairing the long-term damage from Accutane

Posted by Chico Esposito on 25 August 2014 - 12:29 PM

antihistimines, telomeres, cannabis oil load of bollocks the lot of it. Heres a concept for those looking at a supplement to cure their problems, it's not going to happen, believe me i've had this for 11 years and have taken every supplement that you can possibly imagine, and it's all bullshit, straight up.

 

The one thing i'll say honestly is stop looking for symptom relief and actually try to embark on dealing with the cause, the actual core of the problem.

 

Start eating fruits & vegetables, fiber rich foods to heal the colon like Psyllium, chia seeds, flax, hemp seeds, take probiotic rich food like kombucha, water kefir, sauerkraut this will help your colon transit time if your suffering from constipation. Drink teas to cleanse the liver containing (dandelion, licorice, milk thistle, artichoke), likewise do the same for the kidneys, teas containing (parsley, fennel, celery seed, nettle). Eat Sea vegetables, this is one of the few things that pretty much everyone if deficient in, iodine, especially those with skin, hair or nail problems. Add things like wakame, kelp, dulse to salads, try nori wraps, with sprouted mungbeans, iodine is great for healing the thyroid which speeds metabolism, strengthens hair, skin and nails.

 

Add trace minerals from celtic sea salt, buy a few sprouting jars and sprout sunflower seeds for salads, sprout chickpeas etc. Loads of salads, with avocado's tomato's, cucumbers, sea vegetables, sprouted seeds and olive oil and raw apple cider vinegar as dressing (acv helps stomach acid, contains good bacteria and live enzymes). Juice regularly, especially green juices it's the single best vitamin/ mineral supplement you could ever put into your body. Buy a dry skin brush and use it everyday before showering, apply coconut oil to your body instead of lotions, eat coconut oil if your cooking. Don't use flouride in your toothpaste, buy flouride free toothpaste, stop putting chemicals on your skin. Soak nuts 24 hours before eating them, eat quinoa ( i soak mine overnight to reduce phytic acid)

 

Exercise, sweat, practise yoga, it helps move lymph, just like the dry skin brushing. Drink lots of water, get out in the sun as much as possible. Stop looking for a pill to heal the body, it's a combination of all things, physical, mental, spiritual, diet, lifestyle, understanding of nutrition... that's how to heal the body. It's a toxicity condition, hair loss drugs aren't going to help your post accutane hair loss, antihistimines just cover up immune reaction, they cover up inflammation. 




#3448471 Repairing the long-term damage from Accutane

Posted by Chico Esposito on 22 August 2014 - 04:46 PM

Chico, i found a Robert Morse video talking about isotherapy if you are interested: http://www.rawfigs.c...-134/?sid=49680 & www.youtube.com/watch?v=zBzPjxkrbik#t=671

not sure if he's right about the second video as they tested elimination with isotherapy and the result was it increased the elimination of the specific toxin.

 

Thanks alot anonyy i'll check it out.




#3447872 Repairing the long-term damage from Accutane

Posted by Chico Esposito on 18 August 2014 - 06:18 PM

I don't believe in the still there vitamin A theory anymore, it can be true but it's not the true problem, and even if it was there is only one way to expell it same as other toxins. Problem is accutane cause mass cell poisoning and dying, resulting in even more toxicity than before (acne = elimination). You can't regenerate cells when they are being chronically poisoned by their own waste + highly toxic diet who don't even contain anything to truely nourish the body.
If meat is highly toxic it's not because of the vitamin A.

About isotherapy like i said it's not required, it's just to speed up things, and if you want to do it well you need to do sequentially and not only for accutane.

 

Not Vitamin A toxicity per se, specifically 13 cis Retinic acid toxicity. The accutane destroys the gut, as the gut membranes are just like the skin...it causes ineffective removal of the drug. The body was sick already, before accutane, that's why acne was present in the first place. Ineffective detoxification from the kidneys or the biliary tract was probably responsible. The body gets backed up before the drug, the drug is then taken orally but ineffectively removed, so the body stores the drug in the fat cells because fat solubilizes fat. This causes the chronic dry skin, dry lips, and all the same side effects as when on accutane but for the longest time afterwards. Reliving these symptoms is when the accutane is mobilised, which is very dangerous.

 

Of course that's not always the way, some people have no traces of the drug in their body and still have problems due to accutane changing the inner landscape of the body, because it's basically pure poison, but in some cases i do believe the drug is still there. But that's just conjecture at this point, it's just my opinion and i know that it can only be taken at face value.



Apples, oranges, dates, ..

 

Do you recommend or have you used Adrenal Glandular's?




#3385927 Repairing the long-term damage from Accutane

Posted by Chico Esposito on 01 October 2013 - 05:14 PM


 

Chico Esposito, 

 

Please keep us posted.  Curious to see if juice fast is the way to go when so many other methods have failed.  Hope you feel better. 

Day 10 of juice fast, living off 3 quarts of green juice per day, 2 tablespoons of psylium husk, 2 tablespoons of hydrated bentonite clay, lots of water. Everything going smoothly, my eyes are starting to go white again as they were bloodshot before the fast, the red veins are disappearing in the whites of my eyes.... and i feel much better internally. Still have only gone the toilet twice, that needs to be rectified, but going well. My hair looks to be in better shape and body odour has dissipated somewhat.

 

Day 14 of juice fast, 3 quarts of juice, 2 quarts of watermelon juice, 1 quart of Apple, ginger, celery, spinach, lemon juice. Weight starting to stabilise, after losing weight in the last few days, seems my metabolism has slowed down. Arise and shine Bentonite clay has arrived and it replaces the more watery Yerba prima bentonite clay in my shakes. Instead of rice milk i've been using almond milk in my P & B shakes today. Feeling good, skin is still in better condition than pre fast, really a walk in the park today.




#3385289 Repairing the long-term damage from Accutane

Posted by Chico Esposito on 28 September 2013 - 06:28 AM

Day 10 of juice fast, living off 3 quarts of green juice per day, 2 tablespoons of psylium husk, 2 tablespoons of hydrated bentonite clay, lots of water. Everything going smoothly, my eyes are starting to go white again as they were bloodshot before the fast, the red veins are disappearing in the whites of my eyes.... and i feel much better internally. Still have only gone the toilet twice, that needs to be rectified, but going well. My hair looks to be in better shape and body odour has dissipated somewhat.




#3384082 Repairing the long-term damage from Accutane

Posted by Chico Esposito on 21 September 2013 - 07:10 PM

JTM88 and sunnyhatesacne thank you for your fantastic posts, and welcome too you both. Hypervitaminosis A is the cause, the excess fat soluble vitamin A is in the fat, the question is how do we get it out of the body?




#3375139 Repairing the long-term damage from Accutane

Posted by Chico Esposito on 15 August 2013 - 04:40 PM

I was doing some research today after work as I often do and came across a article , it talked about one dermatologist describing Accutane as a

 

CONTROLLED POISONING and he said that he would never give it out to patients but rather recommend dietary changes , supplements and if

 

need be a course of antibiotics , quite a progressive derm I would say , seems like things are changing in the dermatology world and they are

 

finally waking up to the fact that  DIET is a major factor on acne prone individuals , the golden goose that is accutane yes people are finally

 

realizing that it is not a  MIRACLE DRUG as no such thing exists , interesting read though. I would describe Accutane as being in a constant

 

hungover like state with a dose of systemic dehydration thrown in and those would be the mild side effects.

 

 


It's exactly what it is if you think about it.... it's just giving people toxic amounts of synthetic vitamin A to stop their skin from producing sebum. Accutane's not the only medication thats controlled poisoning, chemotherapy is pumping the body full of toxic drugs in the hope that it'll kill some cancer cells. Calcipotriene is a synthetic toxic form of vitamin D that they give people with psoriasis. The sooner you realise the whole world is insane the better, Einstein said it best - only two things are infinite, the universe and human stupidity, and i'm not sure about the former.



#3373350 Repairing the long-term damage from Accutane

Posted by Chico Esposito on 09 August 2013 - 08:02 PM

Camaroz obviously has problems with saw palmetto because he took the male pattern baldness drug finasteride or propecia as it's commonly known. So his body is seriously affected by dht inhibitors or which saw palmetto is a major player. I can totally understand that, as we all know how much a synthetic drug like accutane can mess up our bodies. A normal person can eat cod liver oil and foods high in vitamin A without any problems whatsoever, accutane victims simply can't. Vitamin A f***s them up because accutane has totally messed up their ability to metabolise vitamin A. There are hardly any exceptions to this and joseph is playing a very dangerous game recommending cod liver oil to these people.