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Chico Esposito

Member Since 02 Aug 2011
Offline Last Active Feb 01 2015 07:41 PM

Posts I've Made

In Topic: Repairing the long-term damage from Accutane

30 January 2015 - 06:28 PM

Guess who got diagnosed with Crohn's today !!! biggrin.png

Makes me miss the good old times, when I was just pissed about the hairloss, wrinkling, and devastated mental health.

 

Well i suppose it's good that you've got a diagnosis now. Did you have blood in your stool or any obvious signs before you got checked out? because i have poor digestion myself and was wondering about getting that checked out myself.


In Topic: Repairing the long-term damage from Accutane

26 January 2015 - 05:00 PM

I understand why you do it accutanereallysucks, but i find it in poor taste. Lots of the people on this site have spent thousands upon thousands in the hope that they can get a handle on the side effects caused by this drug, yourself included. Charging people that have suffered enough is not fair game as far as i'm concerned. Your a dermatologist, you don't need the money. Any information that can help those suffering with these debilitating side effects should be out in the public domain, especially seeing as the plight of said people is wholly ignored by the medical establishment. The same establishment that caused the problem in the first place.


In Topic: Repairing the long-term damage from Accutane

22 January 2015 - 07:40 PM

http://liweilab.gene...gi=1592&ti=9606

 

This is the main enzyme responsible for metabolising accutane, is there any way to induce it?


In Topic: Repairing the long-term damage from Accutane

22 January 2015 - 02:59 PM

copper toxicity?

if somone have too much copper can it be an indication for a iron deficency? or maybe for a unavailable iron because of a manganese deficecncy(being used to much for sod2? and for UDP-glucuronosyltransferase which removes the drug?) and more deficiencies which make iron unavialable or unbound?

lets just say for a minute that copper is nedded for iron bounding(it is needed for something for iron but i dont know if for bounding) if the iron bounfing mechanisem needs more then copper, and those more factors are deficent so the complete bounding (stracture?) is not working or being made-could this elevate copper?

_

i dont know chemistry . does this scheme means that  Fe (iron) is being used for the sod mechanisem. or that the sod is against iron?

The SOD-catalysed dismutation of superoxide may be written with the following half-reactions :

http://en.wikipedia...._oxygen_species

  • M(n+1)+ − SOD + O2 → Mn+ − SOD + O2
  • Mn+ − SOD + O2 + 2H+ → M(n+1)+ − SOD + H2O2.

where M = Cu (n=1) ; Mn (n=2) ; Fe (n=2) ; Ni (n=2).

 

Copper is needed to turn Iron from ferric into ferrous and back again. It's pretty important to Iron metabolism. Also superoxide dismutase needs Manganese, Copper and Iron to function properly. B12 and Folate are linked to DNA methylation but they are also partly responsible for Iron metabolism. Zinc increases SOD as well but it's antagonistic to Copper.


In Topic: Repairing the long-term damage from Accutane

22 January 2015 - 02:36 PM

 Accutazed just type in hair mineral test UK in google and you'll get what your looking for.