Yes, Yes it can cause poor circulation. Studies are starting to roll out also that it can effect thyroid function, which Hypothyroid can cause poor circulation & feeling of cold even in warm weather. You should advise your derm...as there are other medical issues that Accutane can cause that are related to poor circulation. Good Luck!
I just took my 1st 20 mg pill yesterday and within a couple of hours my hands felt freezing cold. I read up on it, popped a niacin and it felt a bit better. Then I started feeling pressure in my head - it didn't hurt really, just felt like pressure was building up. This is just one pill! Should I be worried? I am very sensitive to most medications.