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Member Since 27 Dec 2010
Offline Last Active Jul 31 2014 12:31 PM

#3444622 Now What?

Posted by hearts on 31 July 2014 - 12:26 PM

I think you’re right hearts, it’s best not to change too much at once. I’ve just been concerned about medication interactions; this especially true since I don’t have a solid understanding of the details of hormone receptor sites. I’ve read about how certain hormones ‘beat out' other hormones to receptor sites, which then influences your hormonal equilibrium and results in free or unattached hormones (such as ‘free testosterone’). So, I just wasn’t sure if, say, the progesterone from metformin might ‘beat out’ the good estrogen that is metabolized by the DIM and throw off the potential benefits that may be obtained by DIM. I don’t know if this makes any sense or I’m talking nonsense, like I said I don’t have a good understanding of the science behind hormonal receptor sites?


Thank you so much for this link! It is very encouraging and also many parts of it ring especially true for me. For instance, I also have very thick and long hair, so the shedding hadn’t really bothered me until recently. It’s also such a relief to know that it’s safe to take DIM with metformin. You’re such a wizard with research hearts! <3


And thanks for confirming that it seems like I have estrogen dominance, it’s very tricky with those lists because there are always a lot of broadly applicable symptoms.


I'm glad that the review was helpful! (: Another thing that's weird is she has a review on inositol saying that she gained something like 15lbs in 3 months on it. Crazy stuff, haha!

#3444598 Now What?

Posted by hearts on 31 July 2014 - 10:52 AM

Thanks WishClean,

I am nervous about taking everything I am too, but I'm more nervous about quitting the pharmaceuticals cold turkey. I've started the process of weaning off of spiro. Do you think that I should simultaneously start weaning off of metformin? Met basically addresses my insulin issue while also raising my progesterone. Could high progesterone negatively interact with the DIM? It's obviously safe to continue using the inositol with DIM, as you do, right?

I'm sensitive to supplements too, as I've mentioned, which is another reason why I'm nervous about DIM :-S.

Thanks for explaining the error message to me. I hope you were able to diasipher my complement through my mishmash grammar. Lol.


I would advise staying on Metformin for now, at your regular dose. Weaning off or stopping too many things at once is just like starting too many things at once... you won't be able to tell what is causing a problem if there is one. Progesterone will not negatively interact with DIM. If you want an anecdote, read the review on another DIM supplement titled "Continued success with DIM." She apparently takes both DIM and Metformin. Also, it looks like she tried spiro in the past.


About your list of symptoms... most of those really do sound like excess estrogen symptoms to me. I had all of them but acne while on spiro.

#3444383 Now What?

Posted by hearts on 30 July 2014 - 11:25 AM

WOW! Thank you WishClean for your comprehensive research once again! This makes so much sense. Since last summer I’ve been so unhappy because I couldn’t figure out why I’d be getting acne while on—once effective—treatments for acne. Was it the spiro? Was it the glucosmart (inositol)? Was it the vitamins I was taking? And now with this research, and with the information I’ve found on this forum regarding estrogen dominance, I’m starting to understand my situation, which can hopefully provide me with some relief.

The section of the study about breast cancer is especially worrying since the disease runs in my family. I’m also concerned about adrenals since, to my knowledge, it is a more challenging issue to diagnose and treat. I found this link on adrenal issues that is somewhat helpful for self-assessment: http://www.nichd.nih...s/symptoms.aspx. The issue with these self-diagnosing symptomology lists is that many of the symptoms are so common. Do you feel tired sometimes? Yes. Do you like salty food? Yes. Well, you have a disease! I don’t think I have an issue with my thyroid because aside from increased menstrual bleeding and cold feet I don’t have any of the more obvious symptoms, such as a hoarse voice, a puffy face, or weight gain (in fact I’ve lost weight over the last year). Nevertheless, here is a link on the symptomology of thyroid issues: http://womenshealth....-disease.html#d.

I think it is more likely that I have estrogen dominance as a result of prolonged spiro use. But, as I said in another thread (sorry for being all over the place ladies but sometimes you have to in order to quote posters directly and stay on topic), I resisted this diagnosis for so long because I just didn’t understand how estrogen could cause acne when it had always been touted as beneficial to acne by the medical community (birth control!).

Additionally, as I said in another thread, I am eager to get off of spiro but I don’t want to be reckless about it since I had the worst experience of my life when I quit the birth control Diane 35 cold turkey years ago. The acne that had always been concentrated on my chin encompassed my entire face and it was so painful I could barely sleep or eat. I don’t know if you’ve ever had nodular acne WishClean, but it’s the WORST sad.png! In preparation to start DIM, last night I cut my spiro pill into several pieces and ended up taking approximately 87.5mgs (I cut the pill in half-50mgs, then a half in half-25mgs and then a half in half-12.5mg and took those three pieces to total 87.5mgs). I plan to slowly reduce my spiro dose over a period of several months in order to reduce the risk of a rebound. I did this the second time I took and subsequently quit birth control to much better results than the aforementioned cold turkey time (my acne returned but not worse than pre-treatment).

Still, I am nervous to pin my hopes on DIM. And I am nervous to take DIM while still on spiro but I need to treat my acne. I have a very bad nodule at the moment that is impeding my ability to move my mouth without feeling pain sad.png. Do you have any more advice regarding my spiro/DIM dilemma or anything else? I find your and hearts advice and encouragement priceless!


Thank you for your research, WishClean. I suspected something like that kind of behavior from spiro because I didn't get some of the side effects until the one year mark. It makes me really glad that I quit using it.


brenmc, I think it's smart to not quit cold turkey like you said. You are doing the right thing if you want to stop taking it. I weaned down for months because I was scared too... I still did end up breaking out, but you might have a better chance actually starting another anti-androgen whilst weaning down. I used NPC while weaning which helped all the estrogen issues but it wasn't enough to stop all of the acne from returning. I would bet big money that I would have stayed clear if I had used DIM earlier.


It could be your answer, and I don't want to be a downer but it also may not be. DIM works really for some and not others but you don't know if it will unless you try. Nothing has been working for you as of yet and DIM has worked for so many, so of course I think you should give it a shot. I really want you to be clear and not have to deal with acne anymore. It's your choice, though. If after 4 months you don't see any improvement, at least you can knock it off the list. Like I said in the other thread, DIM worked slowly and subtly for me, but I saw some improvement after a couple months. 

#3444379 Inositol's Impact On Hormonal Acne

Posted by hearts on 30 July 2014 - 11:06 AM

Thank you so much for the encouragement about losing the weight caused by inositol! It makes me feel better. (: 10-15lbs makes a big difference on my frame and like you said before, it won't budge even if I work out extra hard. I agree that eating the right foods can give me enough if I feel that I need it later. I found the following list on the SoulCysters forum in a thread about it causing some girls to gain weight from it. I think I can manage to eat some extra hummus if required. (;


Lecithin contains 2100mg per 100g
Chick Peas contains 760 mg per 100g
Brown Rice contains 700 mg per 100g
Wheat Germ contains 690 mg per 100g
Oranges contains 210 mg per 100g
Peas contain 160 mg per 100g
Grapefruit contain 150 mg per 100g
Strawberries contain 95 mg per 100g
Cauliflower contains 92 mg per 100g


I'll respond to the DIM related stuff on your other thread here: http://www.acne.org/...now-what/page-3 I just realized that WishClean's thread was jacked by our DIM discussion. Sorry, WishClean! ):

#3444204 Inositol's Impact On Hormonal Acne

Posted by hearts on 29 July 2014 - 02:03 PM

Hey hearts,

For some reason when I went to amazon.ca and tried to purchase it, at the payment stage it said 'cannot be delivered to your location' or whatever. Perhaps because I live on an island? I don't know. Thankfully, my mom found Nature's Way DIM Plus on another website that would deliver to my location! So I am happily awaiting the Nature's Way brand. I decided it would be best to wait for that one because it has such fantastic reviews.

I'm not sure how much to take because each capsule only contains about 12.5mg of actual DIM, I believe. It does have the added mgs of broccoli and cauliflower powder. How many pills/day did you start with and what do you think a good dose is for me, given my situation?

I know it's been said that it's not a great idea to take DIM with spiro, but I was thinking about it and I don't really understand why that would be, since DIM is also an anti-androgen, why would that have a negative interaction? Either way, I do plan to wean off of spiro if I see improvement with DIM.

Do you have any tips for me while taking DIM Plus? Is there a time of day that I should take it? Should I drink extra water to flush toxins out that way?



Awesome! I'm glad that you were able to find a place that ships it to you. (: Each capsule contains 50mg DIM complex, so 2 capsules is 100mg and the recommended dose. I don't know where you read 12.5mg but you'll see when you get the bottle that it says 100mg per serving. It also has 100mg of veggie powders, so technically each serving is 200mg of total supplement (though not all DIM). I really like the capsules because they are quite small compared to a lot of supplements.


How much spiro are you taking, again? If you have bad painful acne, I would personally just start at 100mg (2 capsules). You can choose to work up if you want, but from my own experience of not working my way up, it doesn't matter. I just wanted to get clear and like I said I even took 150mg to speed things up for a while. I had a bunch of cystic and those hard nodules like you described in the other post, along with a little non-inflamed stuff and DIM cleared all of it. You can always lower the dose once you're clear if you want later. But again, do what you want... you don't have to take my advice!


As far as recommendations for taking it... it's good to take it with food, at least in the beginning. It even suggests this on the bottle. The only —and temporary— side effect that I had was some mild stomach cramping. I read another review on Amazon of someone having that problem as well, and they said food helped. It's probably gas generated from the vegetables or something, haha. I am particularly susceptible to stomach cramping though, like when I eat too much. Anyway, that went away within a couple weeks. After that I could take it on an empty stomach no problem. I don't think time of day matters, though it's maybe worth taking note that testosterone/androgens are higher in the morning. You could space it out from spiro if you want. Since I was taking two capsules a day, I just took one first thing in the morning and one before going to sleep.


Plenty of water is good for you no matter what you are taking! (:


I really hope that it works for you! I can't think of a reason why it would necessarily be dangerous to take with spiro, but just try to pay attention to how you are feeling while taking both and go from there.

#3444008 Inositol's Impact On Hormonal Acne

Posted by hearts on 28 July 2014 - 12:41 PM

Thanks so much for replying hearts! Yikes, what you said about i-3-c and c-d-g makes me nervous! Is the initial breakout with these two almost inevitable then? In the success stories you read about Estrosmart, did they mention an initial breakout?
I bought the Estrosmart because I take the Glucosmart by the same line. But you think just plain DIM would be safer with spiro? The article mentions i-3-c's interaction with birth control pills, so that makes sense. And DIM addresses androgens and estrogen? I obviously have an issue with both, based on my PCOS symptoms. What dose of DIM did you take? What brand?
Thank you!
Did you delete your topic on DIM, I couldn’t find it?

Oh, I didn't mean to scare you! It's not inevitable... not everyone gets an IB with any of these supplements. You may be perfectly fine with Estrosmart, no initial breakouts or anything. I am just trying to give you more information to think about. I considered taking CDG before DIM but after reading anecdotes of girls breaking out from it, I decided to try DIM which had fewer of those stories. I3C does make me nervous if you are taking other medications alongside it, though. In fact, it even says on my bottle of DIM that it is superior to I3C because of it's instability. I'm not super knowledgable on I3C though, so you can take what I'm saying with a grain of salt.
WishClean, am I totally remembering incorrectly or did you try CDG for a little while?
If I remember right, Estrosmart reviews are about the same as other DIM supplements... mixed. It works better for some than others. An IB wouldn't be predictable from these stories. I'm not trying to push you into using it, but the only real way to know would be to try it. Here are some threads on the actual Estrosmart acne board, though!
I took Nature's Way DIM Plus. When I started taking it I was living with my parents who live less than 5 miles from Nature's Way in Utah, so the entire brand was easily obtainable locally and I trusted them. I live in Denver, Colorado now (500 miles away) and I see Nature's Way products here, but not as much of a selection. I took 100mg (two capsules daily) but I was impatient after a month or so and to speed things up I took 150mg (three capsules) for a few months. After I was clear, I lowered the dose back down to 100mg. DIM Plus isn't that expensive ($18 a bottle — $9 a month) but I actually bought a bottle of plain DIM from Piping Rock which I was going to try. It's super cheap ($7 a bottle of 90) and each capsule is 100mg so it would have lasted me three months! I weaned off before trying it, though so it is just sitting in my cabinet unopened, haha. I buy other supplements from Piping Rock (l-cysteine, etc.) and they are great so I imagine that DIM would be good from them too. Not sure if they ship to Canada... If you want me to, I could try to mail you the bottle.
DIM does help with excess estrogen (supports estrogen metabolism) and it is a natural anti-androgen as well. If you suspect that both are a problem, it could be very beneficial to you.
I do think if you want to stay on spiro and add DIM, taking a plain DIM supplement would be the safest and have less risk of side effects. Ultimately it's up to you and what you're most comfortable with, though! (: Ginseng is supposed to be a hormone regulator, and it can also affect blood sugar. I took it for a few weeks (hoping to help hypoglycemia) and saw no difference in absolutely anything, but maybe that wasn't long enough. I just really need to remember to eat to control blood sugar.
Oh, and I did have my thread removed. It had spiraled out of control and I'm strongly considering starting a website that is completely focused on balancing hormones naturally. I repeat myself so many times on other threads and in PMs so I think it would be good to have my experiences and research mostly all in one place.


P.S. To update anyone following my progress with quitting inositol... it has been a little over a month. My skin and hair are still great but I haven't been able to drop the weight, yet. I realize I was taking it for 6 months and it might take a little longer for my hormones to readjust, so I'll continue to be patient.

Sorry for the long post.

#3443900 Inositol's Impact On Hormonal Acne

Posted by hearts on 28 July 2014 - 12:11 AM

Indole-3-carbinol (I3C) is the precursor to DIM. From what I found back in researching the differences between the two, DIM is more stable and has less potential side effects. Here is an article that explains some differences, about half way down the page. I want to point out that it also says the following: 


Since diindolylmethane does not induce the wide array of enzymes that I3C does, there is less of a chance of interaction with other nutrients, hormones or medications. With I3C, antacids and heartburn medications will tend to change an individual’s response due to I3C’s dependence on stomach pH for activation.


It would personally make me nervous to take spiro while taking I3C, where it wouldn't with DIM. Also, it's just my opinion but I don't recommend taking one of those cocktail supplements... you wouldn't be able to know if DIM was helping and CDG was making things worse, for example. I have heard of people having IBs from CDG but of course that's not the case for everyone. I have also read a lot of success stories with Estrosmart, etc. so who knows.


I don't see any problem with taking half the dose and working up if it's not helping enough. My bet would be that a lower dose would give a smaller initial breakout if that were to happen — not prevent it, though. To answer your question, no I did not have an initial breakout with DIM. It worked slowly and subtly until I was just totally clear, about 4 months.


And I agree with your spiro hypothesis. It definitely raised my estrogen levels, even though it's not really supposed to. However, if your acne is caused by excess estrogen or androgens, either way DIM helps with both.

#3442979 Pregnancy And Acne

Posted by hearts on 23 July 2014 - 12:36 PM

michi31, Progesterone (and estrogen) is at its highest during the third trimester. At delivery, both progesterone and estrogen drop significantly, while prolactin levels continue to rise. Using natural progesterone can help prevent postpartum acne as well as other symptoms like hair loss and depression. To lower prolactin levels later (after breastfeeding), you can take some supplements like vitex (which also helps with progesterone) or l-tyrosine.


hCG (human chorionic gonadotropin) also rises during the first 8 weeks or so. Some women start breaking out or have worse breakouts around this time. hCG then begins to drop off again at 13-16 weeks.


Like psychokitty said so well — if you want to have a baby, enjoy the experience and try not to focus on acne. There are things that you can do about it later and you don't want something like that to ruin the time with your new baby or prevent you from having another baby if that's what you want.

#3440660 Seeing A Herbal Medicalist/naturopath

Posted by hearts on 10 July 2014 - 04:53 PM

I've never seen a naturopath but I am familiar with the concept. I just had to reply because I wanted to say, you should DEFINITELY find out what is in the "herbal mix" before you continue to take it. If you have a reaction or generally don't tolerate it, you will need to know why. Knowing the ingredients is extremely important — you could be taking something that is potentially dangerous or that you don't want to be taking. Another (less important) thing to consider is if you want to take it long term, it's very possible that you could get the active ingredient for much cheaper elsewhere.


If he doesn't want to tell you what he's giving you, I would go to someone else. You have the right to know what you are putting into your body. I remember reading an article where a naturopath in the state I used to live in was arrested for not having a license and the woman he was treating actually died. That is an extreme case and I don't mean to scare you, but if he's acting at all shady I would find someone else.


I'm really sorry that you're struggling, though. Try to stay as positive as you can, even though it's extremely difficult. I hope vitex clears you up and you don't have to deal with it anymore. Accutane is an option but usually with hormonal acne it eventually comes back, which it sounds like you've already experienced. Have you considered spironolactone? I just think that it would be a less extreme route and it works for most with PCOS.

#3439193 Dim-Plus: Hormone Regulating Acne Miracle

Posted by hearts on 03 July 2014 - 08:24 AM

I took DIM Plus (made by Nature's Way) which worked for me too. I'd take it again if needed in the future. Here's a link and some info:


Ingredients Per Serving (2 Capsules): 

  • 100mg BioResponse DIM Complex (patented, enhanced bioavailability complex containing 25% diindolylmethane) starch, diindolylmethane, natural vitamin E, phosphatidylcholine (soy) choline, silica
  • 100mg Protectamins® spinach powder, cabbage powder, concentrated broccoli powder
  • 9 IU Vitamin E (as d-alpha tocopheryl succinate)

Other Ingredients: Cellulose, gelatin, chlorophyll

Does Not Contain: Gluten, salt, sugar, wheat, yeast, artificial coloring, flavoring, preservatives or dairy products.


(Women): Take 2 capsules daily with food. (Men): Take 2 capsules twice daily with food. For intensive use (Women & Men): Take up to double the recommended dose.

#3437069 Inositol's Impact On Hormonal Acne

Posted by hearts on 20 June 2014 - 10:55 AM

Hey ladies,


hearts, my regimen now consists of spiro, metformin, zinc and vitamin D. I really didn’t want to go back to metformin and be stuck taking two pharmaceuticals but, sadly, nothing I tried since last summer worked. I kept thinking (and writing on this forum) that the spiro had stopped working, but I now believe it was the inositol that lost effectiveness over time. It’s possible that this had something to do with the brand I was taking or some other factor(s), but I’ll never know. Since being back on metformin my skin has improved (although not to pre-last summer/inositol resistance state).


Previous to any acne treatment, (although after starting and quitting birth control as a teenager, which I started at 15 or 16 to control my heavy period not to address acne because I did not have nodular acne until post-birth control) I would get approximately two nodules a month. After starting and quitting Diane 35 (to address the nodules), I had the worse acne and year of my life as a result of a horrendous rebound effect from quitting Diane (new nodules almost daily). I took spiro and metformin to great success for a couple of years and then inositol and spiro to great effect for a couple more (until last summer). Now back on the spiro and met combo, I still get nodules around my period, which I never did during the “successful years” of these meds. I’m not sure what’s going on here, any ideas (I don’t mean to highjack this post but you ladies are so helpful and it’s related to hearts query about my regimen)?


brenmc, I'm sorry to hear that you are still breaking out around AF, but at least it's an improvement from what it sounds like! I'm unfamiliar with Metformin other than it helps control blood sugar. Seeing as that benefits you so much, it's clear that both you and I had different causes for acne. It also explains why NPC didn't help you when you tried it, so I'm sorry that you bothered with that route at all. ): Again, I'm not that knowledgable on the subject but from what I understand, until insulin resistance is fixed it is very difficult to balance the other hormones.


I'm glad that you seem to have figured out that it wasn't spiro that lost effectiveness, but inositol. Did you ever try D-Chiro inositol or just Myo? Do you think spiro is still helping you? Do you take a multi-vitamin or minerals? There are some other nutrients that help with stabilizing blood sugar including Chromium, Glutamine, B Vitamins (specifically Thiamine), Biotin, and Zinc (which you are already taking.) I'm not saying taking one of these would be a cure all, but they could help. Since taking adequate amounts of vitamins, minerals, and amino acids I have felt much better overall (less dependent on hormonal treatments) and I think without them I wouldn't have been able to wean off of DIM without breaking out.


I'm sorry I'm not more helpful with your situation... my only thought from what you've said is to focus on the blood sugar issues and perhaps the other hormones will start balancing or at least reacting better as well.

#3436921 Inositol's Impact On Hormonal Acne

Posted by hearts on 19 June 2014 - 10:19 AM

@ hearts, glad you are losing weight! Yes, I think thin women tend to gain weight on anti-androgens, that's just one of those things we have to put up with for clear skin. The only time I actually lost weight was on vitex and then on multivitamins....DIM seems to be making me a bit bloated, especially if I take more :/ Not sure why, though....can you think of any reasons? My only guess would be that, along with lowering the bad estrogens, it's increasing the good ones...could that be why?


Yeah, something like that could be a possiblity. The common misconception is that DIM reduces estrogen overall; when it actually just helps with healthy and efficient estrogen metabolism. It increases the chance that estrogen will be broken down into the good metabolites (2-hydroxy) instead of the "bad" estrogen metabolites (16-hydroxy). Also, when you have issues metabolizing estrogen, it leaves extra in your body that can cause negative symptoms... DIM can help with that. I don't think DIM is raising your estrogen, though. 


DIM could be causing you some weight gain and water retention because it's an anti-androgen. It's another one of those that when people take it that need to lose weight, they have great results. My other hypothesis is perhaps that even though DIM is helping you with estrogen metabolism and androgens, your estrogen levels still might be a little high. I used progesterone cream pretty much the entire time taking DIM so that may have helped me. Anytime my estrogen is too high, I just don't feel right and have lots of symptoms. Everyone is different though, so it's hard to say in your case. How much DIM are you taking?


However, with all that being said, apparently inositol lowers testosterone AND estrogen over time... which makes me think in your case that it's more of the anti-androgen effect rather than too much estrogen. If inositol lowers testosterone overall, it would probably explain why I gained some weight and feel generally less toned. I didn't think that taking such a small dose (250mg) of an "unofficial B vitamin" could affect me so much.


Another weird thing about stopping inositol is that I started spotting... I am not due for AF for another week or so. I'm sure it will level out though, I am still using NPC.

#3436760 Inositol's Impact On Hormonal Acne

Posted by hearts on 18 June 2014 - 11:20 AM

Wow, I didn't even think of that. And there I was wondering how I could have gained 5 pounds in just a week hitting my brand new high. So it could be inositol? Crazy. I have taken it for 2 months now. Though I don't think I'm gonna stop, I don't have problems with weight, if anything this is motivating me to exercise more which is great tongue.png


Thanks for the reply, lifelong confusion. It's good to know even more firmly that I'm not alone. However, I'm glad it's working for you! I know that the weight wouldn't be as critical for everyone, so if you like it you should stick with it! (:



Hey hearts! As I mentioned a while ago, I was noticing some bloating with inositol but only during certain times of the month. Now that I added DIM, I think I gained some weight and am retaining more water, but I guess that's the risk to take with any antiandrogen because many women also gain weight on spiro and birth control. Did you gain any weight on DIM, and are you still on it?

Have you tried decreasing your inositol dosage? Perhaps it would work better for you in a b-complex. I read that it helps with weight loss, but my guess is that it only helps with that IF you need to lose weight in the first place. I think on thin women it can have the opposite effect if taken in higher doses. 


Hey WishClean! How is everything going for you? Is the DIM, etc. still working for your skin? I am not taking DIM anymore, I stopped around the end of February. My skin is still really good, though! I didn't notice any side effects on DIM, I just felt that I didn't need it anymore after getting back in balance.


Unfortunately it was more than bloating on inositol for me... during PMS I woujld gain even more but that water retention would drop off and I would be back to the high weight. Rinse, repeat. If I felt more benefit from taking the inositol I would try lowering the dose but there just aren't any reasons to. I took it directly alongside my B-complex so I doubt that had anything to do with it either. Your ideas are great though, hopefully they can help someone else reading this that's going through the same thing! I think you're right about it helping with those who need to lose weight and taking the opposite effect for those who don't. I'm pretty sure that the soul cysters who said they gained weight on inositol were thin or thinner to begin with. It seems like that is the same for spiro and other antiandrogens when I looked into it.



hearts, I don't think I gained weight on inositol but it was nearly impossible for me to lose weight on it. I did every boot camp and workout regimen possible and still couldn’t drop any weight. However, clear skin was more important to me so I stuck with it (until it stopped working last summer).


WishClean, I didn’t know Advil was bad for you. I probably only take it once, maybe twice, per month (as I said, to reduce inflamed nodules). What is bad about Advil? Do you know a natural supplement that helps to reduce inflammation quickly as an alternative?


It definitely seems like a tough balance to achieve, lowering testosterone without increasing estrogen (or estrogen symptoms). It’s super confusing as well. In another post, I wrote about the correlation of spotting and acne, which is apparently a result of low estrogen; however, I have other symptoms of high estrogen, like weight around the waist and lowered sex drive.


I thought you and others on this thread might be interested in this article I found about the correlation between birth control and insulin resistance. This may partly explain the prevalence of PCOS in women of our generation. I would venture to hypothesize that taking birth control early in life may contribute to long-term disruption of the complex relationship between sex hormones and insulin.  http://humrep.oxford.../17/7/1729.long (Re: third paragraph down in the Introduction.


Thanks for the input, brenmc! I feel you on the not being able to lose the weight thing while taking it... it was weird to be gaining weight as the weather warmed up because my activity level goes up quite a bit with hiking, swimming, etc. It's too bad inositol stopped working for your skin... what is your regimen now?


I'm not an advocate of pharmaceuticals or even OTC drugs, but I did do the same thing as you, brenmc — I took Advil (ibuprofen) a few times a month when I was still breaking out and it helped with the inflammation significantly. I have been told by others that stuff like that is really bad for you and even carcinogenic but I have never bothered to look into it. I figured if I only took it occasionally that it would be fine and I don't like to add more paranoia to my life! (: The only negative thing that I know can happen is stomach bleeding when taken excessively or consistently with alcohol. When I was younger, my mom always told me to make sure to have food in my stomach when taking it, which I'm sure helps. As far as natural anti-inflammatory remedies go, I know chamomile, ginger, and turmeric all help, but I haven't tried them topically. Here's some more info on the subject.


Thanks for the link! It's very interesting. I don't think I have PCOS or IR (I do have hypoglycemia) but I know taking BCP early in life really messed up my hormones. If I could go back and not ever take it, I would!


Update on quitting inositol: I have already dropped about 1-2lbs. Let's hope this keeps up! (:

#3427037 Took Spiro For 7 Year... Finally Clear With Low Dose Accutane.

Posted by hearts on 18 April 2014 - 09:52 AM

I'm going to take it for about 6 months. I check my lab work every single month to monitor everything.


And Yes I agree it's a strong drug. But like I've said over and over the people who have these bad side effects 99.99% of the time were unhealthy to begin with OR they got overdosed by their Dr's.


I see you girls are just dead set against accutane and nothing will ever change your mind about it. And that's totally fine. It's not for everyone. You say there have been people who took a small dose who had permanant issues.... I'd really love to meet those people and see their lab work they had prior to taking the drug. I bet they had something off that made them not a good candidate. But there is no way to prove that.


And again the only reason I came on this board was because I tried every single hormonal treatment you could ever imagine with no results. Just want to share my experiance. I didn't mean to get people all worked up. Not my intent.


I'm glad to hear that you don't plan on taking it indefinitely, which is what it kind of sounded like to me. I really don't think it is safe long term.

It's not that I am dead-set against accutane — it just scares me from my own experience and what I see others going through. I think it is over-prescribed and if you are correct about it being overdosed, then I think it seriously needs to be taken off the market until enough studies are done to find the correct and completely safe dose. I also get that some dermatologists are better than others so I think strong drugs like this should be more controlled... for example they have to start at a low dose and then work up if it doesn't help.


It's a little unfair to say those who had bad side effects were unhealthy before starting... everyone is different. Spiro and other treatments didn't work for you and gave you side effects but have worked for others so that argument doesn't really seem valid. Whatever, though... I'm not here to argue with you. I just wanted to offer a different opinion and maybe bring up some points that weren't mentioned before.


I understand that you are just trying to help and I didn't mean to sound like I was bashing your success or efforts. Like I said before, I think accutane is over-prescribed as it is so I wanted to point out that it isn't a miracle drug without consequences for everyone. Again, I'm happy that you found something that works for you and I wish you all the best. (:

#3426805 Inositol's Impact On Hormonal Acne

Posted by hearts on 17 April 2014 - 10:13 AM

I am having such a bad time with acne.....i get 4-5 new painful heads every week...

More than falling hair,I am stressed out because of my face.Its completely covered up by acne and scars.....And the zits hurt so much.

I don't want to go back on birth control pills.Right now,just sticking to inositol.

Has Inositol helped you with acne?If yes,how much time did it take for you to notice any effect??

This battle seems endless.


inpursuit, I had hair shedding for quite a while and was worried about it so I tried taking inositol and choline. It stopped the shedding in its tracks after only a week or two. It's definitely worth a try. If it helps your skin it will be an added bonus! (: