WOW! Thank you WishClean for your comprehensive research once again! This makes so much sense. Since last summer I’ve been so unhappy because I couldn’t figure out why I’d be getting acne while on—once effective—treatments for acne. Was it the spiro? Was it the glucosmart (inositol)? Was it the vitamins I was taking? And now with this research, and with the information I’ve found on this forum regarding estrogen dominance, I’m starting to understand my situation, which can hopefully provide me with some relief.
The section of the study about breast cancer is especially worrying since the disease runs in my family. I’m also concerned about adrenals since, to my knowledge, it is a more challenging issue to diagnose and treat. I found this link on adrenal issues that is somewhat helpful for self-assessment: http://www.nichd.nih...s/symptoms.aspx. The issue with these self-diagnosing symptomology lists is that many of the symptoms are so common. Do you feel tired sometimes? Yes. Do you like salty food? Yes. Well, you have a disease! I don’t think I have an issue with my thyroid because aside from increased menstrual bleeding and cold feet I don’t have any of the more obvious symptoms, such as a hoarse voice, a puffy face, or weight gain (in fact I’ve lost weight over the last year). Nevertheless, here is a link on the symptomology of thyroid issues: http://womenshealth....-disease.html#d.
I think it is more likely that I have estrogen dominance as a result of prolonged spiro use. But, as I said in another thread (sorry for being all over the place ladies but sometimes you have to in order to quote posters directly and stay on topic), I resisted this diagnosis for so long because I just didn’t understand how estrogen could cause acne when it had always been touted as beneficial to acne by the medical community (birth control!).
Additionally, as I said in another thread, I am eager to get off of spiro but I don’t want to be reckless about it since I had the worst experience of my life when I quit the birth control Diane 35 cold turkey years ago. The acne that had always been concentrated on my chin encompassed my entire face and it was so painful I could barely sleep or eat. I don’t know if you’ve ever had nodular acne WishClean, but it’s the WORST ! In preparation to start DIM, last night I cut my spiro pill into several pieces and ended up taking approximately 87.5mgs (I cut the pill in half-50mgs, then a half in half-25mgs and then a half in half-12.5mg and took those three pieces to total 87.5mgs). I plan to slowly reduce my spiro dose over a period of several months in order to reduce the risk of a rebound. I did this the second time I took and subsequently quit birth control to much better results than the aforementioned cold turkey time (my acne returned but not worse than pre-treatment).
Still, I am nervous to pin my hopes on DIM. And I am nervous to take DIM while still on spiro but I need to treat my acne. I have a very bad nodule at the moment that is impeding my ability to move my mouth without feeling pain . Do you have any more advice regarding my spiro/DIM dilemma or anything else? I find your and hearts advice and encouragement priceless!
Thank you for your research, WishClean. I suspected something like that kind of behavior from spiro because I didn't get some of the side effects until the one year mark. It makes me really glad that I quit using it.
brenmc, I think it's smart to not quit cold turkey like you said. You are doing the right thing if you want to stop taking it. I weaned down for months because I was scared too... I still did end up breaking out, but you might have a better chance actually starting another anti-androgen whilst weaning down. I used NPC while weaning which helped all the estrogen issues but it wasn't enough to stop all of the acne from returning. I would bet big money that I would have stayed clear if I had used DIM earlier.
It could be your answer, and I don't want to be a downer but it also may not be. DIM works really for some and not others but you don't know if it will unless you try. Nothing has been working for you as of yet and DIM has worked for so many, so of course I think you should give it a shot. I really want you to be clear and not have to deal with acne anymore. It's your choice, though. If after 4 months you don't see any improvement, at least you can knock it off the list. Like I said in the other thread, DIM worked slowly and subtly for me, but I saw some improvement after a couple months.