6 replies to this topic

[Jason1]

Hello I have taken accutane for about seven months but have been of it for five months now. I have two questions. First what is the total dose that is considered to be the best to prevent relapses. I read that it is 120mg/kg, 125 and 150. Its never clear. Also has anyone had trouble from taking it without food. For probably the first four and a half to five months I was just taking it with a small sip of water and nothing else and then would lay back down or go workout, especially when I was watching my triglycerides. Then I read in the insert that its a must to take it with food. So I start doing that and in the end I wanted to stay on it for one more month but the doc said no. So I told him about how I wasn't taking it with food for the first several months and he said that thats ok. I repeated myself and made reference to the insert but he kept saying that it doesn't matter if you take it with food. My skin still looks good but I am always worried about relapses.

[Rissa]

I have to take mine with food, if I don't I get heartburn and my stomach hurtsif it does'nt affect you taking it without food then I wouldn't worry. I don't know which way is better, but I have heard taking it with food helps it digest better. I don't know about the dosage thing. I've been taking 80mg for 7 months and I was clear after 5 months besides a few clothed pores, so my derm added 2 months. i think it just depends on how you respond to it.

[beentheredonethat]

Absorption is more than doubled when taken with a fatty meal because isotretinoin is fat-soluble.

[thirty dollar bill]

Absorption is more than doubled when taken with a fatty meal because isotretinoin is fat-soluble.

This dude knows everything.

[beentheredonethat]

This dude is a chick!

[Jen121]

Absorption is more than doubled when taken with a fatty meal because isotretinoin is fat-soluble.

What kind of food would you consider a fatty meal?

[beentheredonethat]

A meal... that has fat in it. It's obviously better for you to stick with "good" fats like avocado and olive oil than to eat lots of bad fats like fried foods. But i don't think the type of fat influences Accutane absorption. You need some fat in your diet anyway, so take your Accutane with a meal with some fat. Many people eat a basically fat-free breakfast and should probably wait to take it with a richer meal instead. I take mine at lunch, it's my largest meal and there is almost always some fat in it.

The info at Roche says absorption is more than doubled with a "standardized high fat meal" but i have never seen that term defined.