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Insulin resistance

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#1 geezer

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Posted 25 March 2005 - 06:30 AM

I was doing a research of alpha lipoic acid and ran into this site where it says that there is a connection between insulin resistance and high blood pressure. I myself have always been quite healthy but I have suffered from high blood pressure as long as I can remember. I'm normal weight. When I was younger I used to do lots of sports but I still had high blood pressure and I have never figured what causes it. The site also says that there is a connection between IR and cholesterol. My last health examination was about a year ago and the other thing that I got reminded is that I have too low HDL cholesterol. That's exactly what this site says. Low HDL and high blood fats is caused by high levels of free fatty acids from insulin resistance.

http://www.advice-hg...a/02c54824.html

Anyone else has same experiences?

Just recently I have changed my diet and the results for my skin have been very promising. I cut a lot of stuff from my diet. It's really too early to tell but at the moment I would say that I'm 99% clear. I do not have any active acne just a few red marks that are fading rapidly. Before the change in my diet I used to have active acne all the time. I never thought that the reason for my high blood pressure (and acne) could be my diet coz I ate the same stuff as others. I'm very curious to know what affect this change will have on my blood pressure and cholesterol levels.

Now, the reason why I was studying ALA was coz it is supposed to be very good for helping with insulin sensitivity and balancing your blood sugar levels. The interesting thing is that the site states that basically you shouldn't use ALA but the R-ALA form of it. The normal ALA is actually only 50% ALA and the rest is just unuseful synthetic stuff whereas R-ALA is the 100% organic form. Here's a straight quote from the site why only R-ALA should be used: "In short, when you take a racemic mixture of R(+)- and S(-)-enantiomers found in conventional "lipoic acid" supplements, R(+)-Lipoic Acid improves insulin resistance, while the S(-)-form actually makes it worse. The results that are seen in clinical trials using the racemate, then, are the net effects of combining the powerful benefits of R(+)-lipoic acid, with the sometimes weaker, and sometimes even harmful, effects of the S(-)- form."

Has anyone used insulin sensitizing or blood sugar balancing products like chromium, ALA, NAC or glucomannan? If you have please share your results.

I just recently used NAC for one week but I stopped it because I got skin rashes from it. When I stopped my skin rashes went away. I believe it was a detox reaction.

#2 SweetJade1980

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Posted 25 March 2005 - 01:38 PM

QUOTE(geezer @ Mar 25 2005, 05:30 AM)
I was doing a research of alpha lipoic acid and ran into this site where it says that there is a connection between insulin resistance and high blood pressure. I myself have always been quite healthy but I have suffered from high blood pressure as long as I can remember. I'm normal weight. When I was younger I used to do lots of sports but I still had high blood pressure and I have never figured what causes it. The site also says that there is a connection between IR and cholesterol. My last health examination was about a year ago and the other thing that I got reminded is that I have too low HDL cholesterol. That's exactly what this site says. Low HDL and high blood fats is caused by high levels of free fatty acids from insulin resistance.

http://www.advice-hg...a/02c54824.html

Anyone else has same experiences?

Just recently I have changed my diet and the results for my skin have been very promising. I cut a lot of stuff from my diet. It's really too early to tell but at the moment I would say that I'm 99% clear. I do not have any active acne just a few red marks that are fading rapidly. Before the change in my diet I used to have active acne all the time. I never thought that the reason for my high blood pressure (and acne) could be my diet coz I ate the same stuff as others. I'm very curious to know what affect this change will have on my blood pressure and cholesterol levels.

Now, the reason why I was studying ALA was coz it is supposed to be very good for helping with insulin sensitivity and balancing your blood sugar levels. The interesting thing is that the site states that basically you shouldn't use ALA but the R-ALA form of it. The normal ALA is actually only 50% ALA and the rest is just unuseful synthetic stuff whereas R-ALA is the 100% organic form. Here's a straight quote from the site why only R-ALA should be used: "In short, when you take a racemic mixture of R(+)- and S(-)-enantiomers found in conventional "lipoic acid" supplements, R(+)-Lipoic Acid improves insulin resistance, while the S(-)-form actually makes it worse. The results that are seen in clinical trials using the racemate, then, are the net effects of combining the powerful benefits of R(+)-lipoic acid, with the sometimes weaker, and sometimes even harmful, effects of the S(-)- form."

Has anyone used insulin sensitizing or blood sugar balancing products like chromium, ALA, NAC or glucomannan? If you have please share your results.

I just recently used NAC for one week but I stopped it because I got skin rashes from it. When I stopped my skin rashes went away. I believe it was a detox reaction.

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Yes, Yes, Yes, and not quite ;-)

Yes Insulin Resistance appears to be at the center of quite a few "preventable" diseases and Low HDL and High Blood Pressure are but two of these. Furthermore, in twins with acne, they found a connection with them lacking enough Apolipoprotein A, which is a component of building HDL! So if you have Low HDL or Low-Normal HDL compared to your levels of LDL, then Insulin Resistance and/or your diet may be at play.

As for the ALA, yes it helps with stabilize blood sugar, better than NAC, helps increase glutathione levels (acne sufferers and those with IR seem to also have less of this), and is overall and good antioxidant. So definately good job at reaserching but recently I discovered that R-ALA can be quite dangerous. It has the ability to polymerize (form rubbery like balls) and lose it's effectiveness quickly and if it's rubbery balls in your stomach (due to the heat in transportation/storage or due to the reactions from your stomach acids) that means you may not be able to digest it at all!!!

It is now recommened that despite the negative effects of S-ALA, that you are better off taking 2 - 3x the amount of ALA than you are at taking R-ALA. ALA will end up being MORE effective than R-ALA because of the reactions that occur with R-ALA.

Now, if you choose to still use a pure formula, you have a few options.


Gel R-ALA (safest form of R-ALA)
http://www.geronova....ategory_Code=RG


Liquid K-RALA (or some other mineral attached to the R form to stop if from polymerizing)
http://www.geronova....egory_Code=LRAK



Capsule K-RALA

100mg
http://www.easycart....Inc./search.cgi (search for K-rala)
http://www.vitacost....earchText=r-ala

200mg
http://www.superiorn...ducts/krala.htm


Powder K-RALA
http://www.1fast400....A_1Fast400.html
https://secure3.m6.n...i2le/order.aspx
http://www.superiorn...ducts/krala.htm


R-DHALA (in liquid capsules) - the reduced form of R-ALA, so that the body can convert/oxidize it to R-ALA
http://search.lef.or...oic alpha acid
http://www.geronova....ategory_Code=MG


Here's some more info:
http://www.geronova.com/krala.htm
http://www.imminst.o...T&f=6&t=3970&s=
(there's some other forums but I can't find them right now)
These are not steps, but stages some people progress through when going from conventional to holistic medicine. Stage 2 is how I became 99%+ Clear, eliminated my dysmennorhea, significantly reduced my sebum & pore size, etc & is my predominant method.

Stage 1 (Treatment):
* (Daily) Isocare Skin Control Cleanser, Dream Products Customized Natural Face Lotion & Coppertone Sport Spray Sunscreen (mixed)
* (Sporadically) spot treat w/ anti-inflammatory (neosporin, hydrocortisone, salicylic acid) or a skin lightener (post-inflammatory pigmentation) to treat stubborn cystic/nodular acne that appears due to unknowingly or knowingly ingesting a food/ingredient that breaks me out (I do my best to avoid these foods). If you cover treated area w/ a bandaid, it makes product more effective.

Stage 2 (Prevention): "cheapest" method ~ Since Aug. 2002
* Follow a Gluten-Free, Trans-Fat Free, Dairy-Free and No Added Sugar diet for my Insulin Resistance/Hyperandrogenism (Silent Chronic Inflammatory Syndrome)
* Avoid ALL types of nuts and the Genus Prunus (almonds, plums, peaches, nectarines, apricots, cherries), Bananas, Pineapples, Cottonseed oil, Artificial Sweetners.

Stage 3 (Correction):
* 1/18/08 Ultimate Colon Cleanse (30 day program)

Research:
* Developing functional foods for those with acne & other special needs (assuming there's a defficiency).
* Developing good & "safe" formulas for various hormonal issues for women. Correction stage may resolve this for some.

#3 geezer

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Posted 25 March 2005 - 03:07 PM

SweetJade, thanks for the links and info on R-ALA.

Do you have a clue why ALA hasn't the ability to polymerize but R-ALA does? Does the S-ALA part somehow prevent this?

#4 SweetJade1980

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Posted 25 March 2005 - 03:19 PM

QUOTE(geezer @ Mar 25 2005, 02:07 PM)
SweetJade, thanks for the links and info on R-ALA.

Do you have a clue why ALA hasn't the ability to polymerize but R-ALA does? Does the S-ALA part somehow prevent this?

View Post



Yup it's because it's a reacemic mixture so it is more stable in that sense. R-ALA not only polymerizes but converts into S-ALA as well, so in that case it is safer to go with ALA or one of the newer versions of R-ALA.
These are not steps, but stages some people progress through when going from conventional to holistic medicine. Stage 2 is how I became 99%+ Clear, eliminated my dysmennorhea, significantly reduced my sebum & pore size, etc & is my predominant method.

Stage 1 (Treatment):
* (Daily) Isocare Skin Control Cleanser, Dream Products Customized Natural Face Lotion & Coppertone Sport Spray Sunscreen (mixed)
* (Sporadically) spot treat w/ anti-inflammatory (neosporin, hydrocortisone, salicylic acid) or a skin lightener (post-inflammatory pigmentation) to treat stubborn cystic/nodular acne that appears due to unknowingly or knowingly ingesting a food/ingredient that breaks me out (I do my best to avoid these foods). If you cover treated area w/ a bandaid, it makes product more effective.

Stage 2 (Prevention): "cheapest" method ~ Since Aug. 2002
* Follow a Gluten-Free, Trans-Fat Free, Dairy-Free and No Added Sugar diet for my Insulin Resistance/Hyperandrogenism (Silent Chronic Inflammatory Syndrome)
* Avoid ALL types of nuts and the Genus Prunus (almonds, plums, peaches, nectarines, apricots, cherries), Bananas, Pineapples, Cottonseed oil, Artificial Sweetners.

Stage 3 (Correction):
* 1/18/08 Ultimate Colon Cleanse (30 day program)

Research:
* Developing functional foods for those with acne & other special needs (assuming there's a defficiency).
* Developing good & "safe" formulas for various hormonal issues for women. Correction stage may resolve this for some.


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