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Spiro Not Working! :(

oily skin spiro acne

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#1 smichelle

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Posted 24 August 2014 - 04:15 PM

Hey guys...

 

So I've been on a low dose of 0.25 mg twice a day(0.5 mg total)…It's now been 2 months exactly and I've seen no improvements at all. My skin is extremely extremely oily, and I cannot control it. Should I be moving up a dose? Does it take longer to work? If it doesn't work for me does this mean that my androgens aren't the issue? Any advice please...

 

Thanks :)



#2 Like Moonlight

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Posted 24 August 2014 - 10:05 PM

Hey guys...
 
So I've been on a low dose of 0.25 mg twice a day(0.5 mg total)…It's now been 2 months exactly and I've seen no improvements at all. My skin is extremely extremely oily, and I cannot control it. Should I be moving up a dose? Does it take longer to work? If it doesn't work for me does this mean that my androgens aren't the issue? Any advice please...
 
Thanks :)


Spiro takes time to work about 6 months before girls notice a marked improvement. Your dose is very low too. Maybe try upping it to 75mg I am on 100 mg and I have no oil issues or acne to speak of, I've been on spiro for 16 months.
Regimen:
AM: CeraVe foaming face wash, 100mg Spirolactone
PM: CeraVe foaming face wash, witch hazel, Acne.org AHA+
Been taking Sprio since 1/2013

#3 hughesan91

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Posted 30 August 2014 - 11:10 AM

Are you sure your dose is 0.25 mg? I don't think spiro is manufactured at that low of a dose. Likely 25 mg. In any case, I take 50 mg twice a day and have for 2 years now. It took a while (~3 months) to see a difference, but the number of days I woke up without new pimples was the first thing I noticed. I used to get a few new cysts a week, and that also began to slow. It made me slightly less oily after that, but this was a less noticeable effect.

Are you taking the spiro with food? Unlike a lot of meds that recommend this, spiro won't make you nauseous if you take it on an empty stomach, BUT it is significantly better absorbed if taken with food. I usually take a spiro after breakfast and after dinner. You don't want to take it too close to bedtime, as it is a diuretic and disrupted sleep is the enemy of healing skin.

Are you taking anything other than spiro?

Edited by hughesan91, 30 August 2014 - 11:11 AM.


#4 smichelle

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Posted 31 August 2014 - 09:47 AM

Are you sure your dose is 0.25 mg? I don't think spiro is manufactured at that low of a dose. Likely 25 mg. In any case, I take 50 mg twice a day and have for 2 years now. It took a while (~3 months) to see a difference, but the number of days I woke up without new pimples was the first thing I noticed. I used to get a few new cysts a week, and that also began to slow. It made me slightly less oily after that, but this was a less noticeable effect.

Are you taking the spiro with food? Unlike a lot of meds that recommend this, spiro won't make you nauseous if you take it on an empty stomach, BUT it is significantly better absorbed if taken with food. I usually take a spiro after breakfast and after dinner. You don't want to take it too close to bedtime, as it is a diuretic and disrupted sleep is the enemy of healing skin.

Are you taking anything other than spiro?

Hi!

Sorry, I totally am taking 25 mg twice a day, not 0.25..my bad hehe. I do take it with food as well…Other than spiro I am taking Testo Quench for Women which is just a natural supplement to help androgen sensitivities. I am seeing my doctor next Monday and was thinking of asking for a higher dose? Or should I wait until the 6 month mark...



#5 Like Moonlight

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Posted 31 August 2014 - 11:24 AM

I would for sure ask for a higher dose. 100mg is the dosage that most women see results at without getting side effects. I would try to get on that dosage if your doctor thinks it's safe for you.
Regimen:
AM: CeraVe foaming face wash, 100mg Spirolactone
PM: CeraVe foaming face wash, witch hazel, Acne.org AHA+
Been taking Sprio since 1/2013

#6 Green Gables

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Posted 02 September 2014 - 12:06 AM

I also started out on 50mg total a day and that does was too low for me to see improvement. 

 

Also, what color are your pills? Many people have better luck with the spiro generic that is yellow colored (instead of the white colored ones). If you have white pills currently, try changing pharmacies. I think most Walgreens sell the yellow Amneal version of spiro.


Edited by Green Gables, 02 September 2014 - 12:07 AM.


#7 paigems

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Posted 03 September 2014 - 09:25 PM

I took 25 mg once a day, and it worked well for my skin, but I had to wait over 6 months to see results.



#8 smichelle

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Posted 05 July 2015 - 08:00 PM

Just wanted to let you guys know and seeee if I can get any advice .. That I switched to a higher dose spiro as of March 29th 2015. I began taking 50mgs twice a day. The increase still hasn't helped my oily skin.

Should I go higher ? Or maybe I was right and hormones(androgens) aren't causing my oil?

Help :(

#9 tracy521

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Posted 16 July 2015 - 08:10 AM

are you currently breaking out on it? i've been on spiro for years and my skin is just as oily as before but i no longer breakout. i would give the spiro a full 6-9 months to work before you up the dosage. it takes time to work. good luck!

#10 megtree

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Posted 16 July 2015 - 10:23 AM

Hi - Spiro takes a loooooooooooooooooooooooooooooooooooooooooooooooooooooooooong (emphasis on really, agonizingly long) time to start clearing you. You might want to wait another month or so on the higher dose to see if you are noticing a difference. The effect is very gradual, so if you are having cystic breakouts or your acne is scarring, you may want to ask your derm for something to reduce inflammation in the mean time. 

If you aren't seeing a difference in 3 months or so (given that you have been on the drug for much longer), I would move on to something else. 
My Accutane log (with pictures): Holy Isotretinoin Batman It's another Accutane Log!
26 y/o female- approx. 54kg
Absorica -40 mg, 1 daily, December 26, 2013 - February, 25, 2014
Absorica - 60 mg, 1 daily. February 26, 2014 - July 6th 
Probiotic - 1 daily
Fish oil supplement w/ vit D - 1 daily
 
Morning:
Cetaphil cleanser
Food Grade Rose water - Toner
La Roche Posay Mineral Water Spray
Vichy 50+ Capital Soleil Cream for Sensitive Skin
 
Night:
Cetaphil Cleanser
Food grade Rose Water - Toner
Ziana (tretinoin/clinda combo) August, 2014 - Current
La Roche Posay Mineral Water Spray
Aveeno Positively Radiant intensive night cream
Cerave Facial Moisturizing Lotion- PM
Avene Cicalfate (as needed)


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