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What Other Antibiotics Work For Acne?



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#1 MattThomas

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Posted 25 July 2014 - 04:40 PM

Antibiotics seem to be the only treatment which actually works effectively for me, I normally have moderately severe acne but when using antibiotics I stay around 90% clear until I inevitably become resistant. So I was wandering what other antibiotics are effective for acne and which of these would you guys recommend for when/if I get resistant to Cephalexin so that I can kind of plan ahead?

 

I've been on (in order):

Lymecycline (least effective)

Doxycycline (most effective)

Erythromycin

Oxytetracycline

 

And I'm starting to get resistant to Oxytetracycline so I've decided to give Cephalexin ago asap.

 

All help is greatly appreciated!! :)



#2 Harry1993

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Posted 25 July 2014 - 05:43 PM

Accutane.

 

No point just putting loads of crap drugs into your system if they're not working, they seem to only be a temporary fix anyway. 



#3 MattThomas

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Posted 25 July 2014 - 05:52 PM

Accutane.

 

No point just putting loads of crap drugs into your system if they're not working, they seem to only be a temporary fix anyway. 

 

I appreciate your advice, really, but I'm just too scared to take accutane at even ultra low doses due to the possible adverse effects.

I'm only 17 so I'm really only looking for a temporary fix until I hopefully grow out of acne like everyone else did in my family around at around 18-19 of age.



#4 lukii

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Posted 26 July 2014 - 05:14 AM

Have you tried topical antibiotics like Isotrexin (retinoid plus erythromycin) or Duac (benozyl peroxide plus clindamycin)? Maybe there's no need to take internally antibiotics?



#5 MattThomas

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Posted 27 July 2014 - 07:31 AM

Have you tried topical antibiotics like Isotrexin (retinoid plus erythromycin) or Duac (benozyl peroxide plus clindamycin)? Maybe there's no need to take internally antibiotics?

 

I've tried all sorts of topicals like benzoyl peroxide, zineryt, differin and so on but I just find them really tedious since my acne is not limited to my face- I have acne all over my neck, shoulders, back, upper chest and arms, even some on my legs D: so having to apply twice a day not only takes a while but it also costs quite a bit and it's just not worth it since they also make my skin really red and dry, meanwhile oral antibiotics are so convenient and effective; I have never had even mild side effects from internal antibiotics and they seem to clear the acne all over my body really well.

 

Thanks for the reply by the way :)



#6 wallbutterfly

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Posted 27 July 2014 - 07:50 AM

*

Edited by wallbutterfly, 04 August 2014 - 11:39 AM.


#7 ICuredAcne

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Posted 27 July 2014 - 09:27 AM

I strongly advice you to stay away from antibiotics. They can make your acne even worse than before taking it. It kills the whole gut flora, acne may disappear for a few weeks but it is short term solution.



#8 Quetzlcoatl

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Posted 27 July 2014 - 03:27 PM

Bactrim (trimethoprim/sulfamethoxazole). High potential for side effects; flu-like symptoms could be signs of a sulfa allergy. Accutane is probably safer and more effective in the long term, although Bactrim will get you results quickly - probably within a week or two.

 

I would advise against antibiotics in general, though.



#9 MattThomas

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Posted 27 July 2014 - 05:17 PM

I strongly advice you to stay away from antibiotics. They can make your acne even worse than before taking it. It kills the whole gut flora, acne may disappear for a few weeks but it is short term solution.

 

Bactrim (trimethoprim/sulfamethoxazole). High potential for side effects; flu-like symptoms could be signs of a sulfa allergy. Accutane is probably safer and more effective in the long term, although Bactrim will get you results quickly - probably within a week or two.

 

I would advise against antibiotics in general, though.

 

Thanks for the help guys and gals, I'm a really skinny 6ft 3 guy weighing at just 60kg :S Do you peeps think that something like 10mg/day would suffice for moderately severe acne? That works out at a little under 0.17mg/kg/day (I think, I haven't really looked into isotretinoin yet). Obviously I'm going to do a bit more research and talk to my derm before even considering accutane, but I just wanted to generally know how little you guys think I would probably be able to get away with and suggest whether the dosage would be safer than antibiotics or not, so I have a more realistic idea.

 

And although obviously more than welcome, I'm not really looking for full remission since it's likely that I will just grow out of acne in a couple of years but would it be safe to take this dosage for up to a year for example? I know that the higher the dose, the more likely remission is achieved yet the higher chances of adverse effects which makes me want to go as low as possible.



#10 courts93aus

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Posted 28 July 2014 - 01:17 AM

Hi!

I absolutely know how you feel!

I tried every antibiotic out there, often being on each course for 4 months without seeing a difference. It was so disheartening and I was so worried about what the effects of all those needless chemicals would be doing in my body.

 

For the record, I have moderate/severe acne and have for 6 years. Im 21 now and just feel as though Im entitled to lovely, clear skin haha.

 

I saw a derm three months ago. After the requisite blood tests etc, he put me on 20mg once per day. Its now the end of my second month. Only some very minor side effects; dry lips (easily cured with carmex) and stiff knees. 

 

My biggest problem area has always been my chin area. So far, the acne of my forehead and cheeks has basically cleared, but I still have a couple of bumps on my chin that just keep coming back. 

 

My honest opinion for you; if your derm okays it, go on accutane. The antibiotics will NEVER work long term. And, if you are like me, you may be genetically predisposed to suffer both teenage and adult acne - meaning your skin most likely wont clear. 

 

Im only on 20mg per day and will remain on the treatment for 12 months. Ive heard of some people being on 60mg and even 80, so my dose is pretty low and low risk. 

 

My derm did say that there has been a lot of recent research which has found that accutane works better and has better and more sustained long term benefits if a low dose is taken over a longer period time. This is very different to how accutane has been used up until now which was basically go on a high dose for 4 months. 

 

The only other thing i can say is what my derm said to me 'accutane does come with side effects, but antibiotics arent no walk in the park either'. If you take care of yourself and take it easy, chances are that you would be fine :)

 

Good luck! 



#11 k3tchup

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Posted 28 July 2014 - 02:46 AM

I would actually encourage antibiotics for short term, acute usage as a gateway to other treatments. For example taking tapering dosages for 2-4wks will allow for better control initial breakout often seen with topicals like differin and retin a.

 

Taking a probiotic will help minimize complications and side effects of antibiotic therapy. This is slowly catching on in the hospital setting where patients are on IV antibiotics for weeks.


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#12 MattThomas

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Posted 28 July 2014 - 07:44 AM

I would actually encourage antibiotics for short term, acute usage as a gateway to other treatments. For example taking tapering dosages for 2-4wks will allow for better control initial breakout often seen with topicals like differin and retin a.

 

Taking a probiotic will help minimize complications and side effects of antibiotic therapy. This is slowly catching on in the hospital setting where patients are on IV antibiotics for weeks.

Yeah I was actually thinking that if I did end up going on isotretinoin for example that maybe antibiotics would help prevent or at least better control the initial breakout. However I understand that Tetracycline antibiotics can interact with normal vitamin A so would I be right in guessing that they would also interact with isotretinoin? And if so, what about alternative antibiotics such as Cephalexin? 

 

And I have been taking probiotic supplements ever since I starting taking all these antibiotics and they seem to be working since as I said, haven't had any noticeable side effects...yet!! Thanks for the help :)

 

 

Hi!

I absolutely know how you feel!

I tried every antibiotic out there, often being on each course for 4 months without seeing a difference. It was so disheartening and I was so worried about what the effects of all those needless chemicals would be doing in my body.

 

For the record, I have moderate/severe acne and have for 6 years. Im 21 now and just feel as though Im entitled to lovely, clear skin haha.

 

I saw a derm three months ago. After the requisite blood tests etc, he put me on 20mg once per day. Its now the end of my second month. Only some very minor side effects; dry lips (easily cured with carmex) and stiff knees. 

 

My biggest problem area has always been my chin area. So far, the acne of my forehead and cheeks has basically cleared, but I still have a couple of bumps on my chin that just keep coming back. 

 

My honest opinion for you; if your derm okays it, go on accutane. The antibiotics will NEVER work long term. And, if you are like me, you may be genetically predisposed to suffer both teenage and adult acne - meaning your skin most likely wont clear. 

 

Im only on 20mg per day and will remain on the treatment for 12 months. Ive heard of some people being on 60mg and even 80, so my dose is pretty low and low risk. 

 

My derm did say that there has been a lot of recent research which has found that accutane works better and has better and more sustained long term benefits if a low dose is taken over a longer period time. This is very different to how accutane has been used up until now which was basically go on a high dose for 4 months. 

 

The only other thing i can say is what my derm said to me 'accutane does come with side effects, but antibiotics arent no walk in the park either'. If you take care of yourself and take it easy, chances are that you would be fine :)

 

Good luck! 

 

Wow haha such a massive reply, thank you, really appreciate it!! :)

 

All you people are definitely making me less hesitant to consider accutane, it also would be a plus since I have EXTREMELY oily skin so it would potentially kill two birds with one stone. I did noticed that you and also nearly everyone else said that they got dry lips from taking accutane, but did it also make your skin overly dry? Funnily enough I had extremely dry skin before quitting the regimen last year and my skin was actually flaking which was nearly as bad as the acne itself, so do you think it would normalize my sebum production or overdry it? It wouldnt be that much of a problem but I had to use moisturiser with jojoba oil all over my face to remedy it which looked really odd in the sun since it made my entire face- even my jaw look really oily and shiny haha


Edited by MattThomas, 28 July 2014 - 07:47 AM.


#13 courts93aus

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Posted 28 July 2014 - 07:16 PM

Haha sorry :)
My skin has gone a little dry, but a light, oil free moisturizer turns it around. I tried using heavier creams and oils such as rosehip and jojoba but my skin reacted badly. Skin definitely becomes more tempestuous on accutane.

#14 Quetzlcoatl

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Posted 30 July 2014 - 05:31 PM

Oily skin is a nutrition problem. Accutane will reduce the oil while you are on the drug, but it will be back at most a month after your last pill.

 

10mg/day is a fine starting dose. You'll probably want to increase it over time. If you're going to take accutane, I would skip antibiotics and their harmful side effects altogether, especially since antibiotics are certainly only temporary.



#15 SquirrelMonkey

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Posted 30 July 2014 - 11:25 PM

I strongly advice you to stay away from antibiotics. They can make your acne even worse than before taking it. It kills the whole gut flora, acne may disappear for a few weeks but it is short term solution.


My experience exactly...I hate what antibiotics have done to my skin. I was on trimethoprim only.

#16 k3tchup

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Posted 31 July 2014 - 12:45 AM

I strongly advice you to stay away from antibiotics. They can make your acne even worse than before taking it. It kills the whole gut flora, acne may disappear for a few weeks but it is short term solution.


My experience exactly...I hate what antibiotics have done to my skin. I was on trimethoprim only.

Take a probiotic and a prebiotic. Drink lots of water throughout the day. True for any A/B. 

 

I wouldn't say oily skin is a nutrition problem, more like a hormonal problem that is indirectly effected by nutritional and dietary choices. 


A nurse is not what you do, its what you are..I am a nurse: its not what i do, its what i am.

 


#17 MattThomas

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Posted 31 July 2014 - 09:36 AM

 

I strongly advice you to stay away from antibiotics. They can make your acne even worse than before taking it. It kills the whole gut flora, acne may disappear for a few weeks but it is short term solution.


My experience exactly...I hate what antibiotics have done to my skin. I was on trimethoprim only.

Take a probiotic and a prebiotic. Drink lots of water throughout the day. True for any A/B. 

 

I wouldn't say oily skin is a nutrition problem, more like a hormonal problem that is indirectly effected by nutritional and dietary choices. 

 

Yeah unfortunately my oily skin is hereditary- cleaning up my diet and taking different supplements has maybe made a very slight difference but my face is still sleek with oil not 2 hours after showering :S



#18 k3tchup

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Posted 31 July 2014 - 01:34 PM

 

 

I strongly advice you to stay away from antibiotics. They can make your acne even worse than before taking it. It kills the whole gut flora, acne may disappear for a few weeks but it is short term solution.


My experience exactly...I hate what antibiotics have done to my skin. I was on trimethoprim only.

Take a probiotic and a prebiotic. Drink lots of water throughout the day. True for any A/B. 

 

I wouldn't say oily skin is a nutrition problem, more like a hormonal problem that is indirectly effected by nutritional and dietary choices. 

 

Yeah unfortunately my oily skin is hereditary- cleaning up my diet and taking different supplements has maybe made a very slight difference but my face is still sleek with oil not 2 hours after showering :S

 

Dude i get it after i shave the next day it is super annoying as it makes ya look like an oil well. I hear its pretty common problem to which i have recently been reading on. Some are suggesting an astringent or a soap that acts the same way, but it all sounds counter intuitive to splash alcohol on my face from what i have learned. But i will probably try something as its quite annoying. Not much a guy can do besides overdose on vitamin b5 or vitamin A which i'd rather not. 


A nurse is not what you do, its what you are..I am a nurse: its not what i do, its what i am.

 


#19 tracy521

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Posted 01 August 2014 - 08:25 AM

you can try minocycline or keflex but you need some sort of skincare regimen to keep those pores clear. have you ever used AHA? if not i would try that once you get on a good antibiotic and then once you are clear for a few months then you can slowly wean off. 



#20 silverlight22

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Posted 02 August 2014 - 10:31 PM

Antibiotics seem to be the only treatment which actually works effectively for me, I normally have moderately severe acne but when using antibiotics I stay around 90% clear until I inevitably become resistant. So I was wandering what other antibiotics are effective for acne and which of these would you guys recommend for when/if I get resistant to Cephalexin so that I can kind of plan ahead?

 

I've been on (in order):

Lymecycline (least effective)

Doxycycline (most effective)

Erythromycin

Oxytetracycline

 

And I'm starting to get resistant to Oxytetracycline so I've decided to give Cephalexin ago asap.

 

All help is greatly appreciated!! smile.png

 

Ok so.. I know you don't want to hear this and trust me I hate hearing this too but antibiotics will eventually make your situation worse. And I say this because I was on Doxycycline for 8 months before it lost it's effectiveness and then Minocycline for 7 months before I became immune to it.

Now I am very very close to going on Keflex/Cephalexin but I know it is a temporary fix. Here is what you need to know - antibiotics will destroy your good bacteria in your gut. They will promote a type of  yeast infection known as Candida which will cause leaky gut syndrome. As a result you will become allergic to a lot of food (rice, bread and anything with sugar especially chocolates and any type of junk food). It will also make sure you do not grow out of acne.

Now here is the thing. You have been on probiotics ever since you started antibiotics. In my case, I did not do that. I started with probiotics after using doxy. So my gut flora and good bacteria got pretty much wiped out. But I don't know if that is your case or not. Try stopping antibiotics for 2-3 weeks and I have a strong feeling you might break out pretty bad. Antibiotics stop you from growing out of acne..trust me.

But you know what, I am as addicted to them as you are and that is why I am considering Keflex now. Or even Bactrim. Even though I do know the side effects and know that I am making my condition worse in the long run. But I have reached a point where I do not care. I am 22 and my siblings grew out of acne when they were 18. I didn't because I used antibiotics. And if you think I am a rare case, trust me, 9/10 people have their acne return worse than it was after antibiotics. 

 

So now you have a choice. To go for them and be happy temporarily (6-7 months) or to stop taking them and look for an alternative cure. Till this day I think my biggest mistake was going on antibiotics. It made my acne worse when I went off it and I wish I had the knowledge I did back then to cure myself without ingesting meds. 


I know you dont wanna hear this and i mentioned i hated hearing this too but this is the sad reality.

But to answer your question - Minocycline, Keflex, Bactrim should be your next abx. 






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