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Mood Changes And Depression On Accuatane

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It's not known if isotretinoin itself can cause depression.

Are you going to a therapist and/or taking antidepressants? I ask because some programs require you to go for one, and that antidepressants can cause mood swings early in the program.

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In my opinion it could be just moodiness/mood swings because you were already depressed. It's best to stick with the isotretinoin for now.

If you get unbearable side effects like severe joint pain or cracked, bleeding lips, go back to the derm.

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It's not known if isotretinoin itself can cause depression.

Are you going to a therapist and/or taking antidepressants? I ask because some programs require you to go for one, and that antidepressants can cause mood swings early in the program.

No im not going to a therapist or taking anti-depressants

In my opinion it could be just moodiness/mood swings because you were already depressed. It's best to stick with the isotretinoin for now.

If you get unbearable side effects like severe joint pain or cracked, bleeding lips, go back to the derm.

Ok thanks

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You're welcome! :)

Message me any time if you have more questions.

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No one on this board can help you! You need to let your parents know and your physician....Yes it has been proven that Accutane can cause depression and other psychiatric disorders in some that may continue even after the medication has been stopped. It is documented extensively in the Rx information for a reason and if your in the U.S. then you sign papers or your parents do.

Please let someone know as we are not doctors!


The secret of health for both mind & body

is not to mourn for the past, not to worry about the future, or not anticipate troubles, but to live the present moment wisely and earnestly.

The Buddha


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While a lot of the research is pointing "no" to isotretinoin causing depression, it still isn't entirely ruled out, and any correlations/possibilities/side effects of unknown incidence must be in the warnings by law.

Edit: Well, yes, he should go back to a derm. Here's what the FDA says:

"All patients treated with isotretinoin should be observed closely for symptoms of depression [emphasis mine] or suicidal thoughts, such as sad mood, irritability, acting on dangerous impulses, anger, loss of pleasure or interest in social or sports activities, sleeping too much or too little, changes in weight or appetite, school or work performance going down, or trouble concentrating, or for mood disturbance, psychosis, or aggression. Patients should stop isotretinoin and they or their caregiver should contact their healthcare professional right away if the patient has any of the previously mentioned symptoms. Discontinuation of treatment may be insufficient and further evaluation may be necessary."

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