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The Evolutionary Biology Behind Acne

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Everyone carries the "acne gene" , most people, however, do not encounter their trigger.

Maybe. Because the issue isn't necessarily the genes. Turns out after all the mapping was done, we don't have that many genes. It's the enzymes. And they are switched on and off by what you do to yourself or by what your parents did and then are passed down to you. In the study involving epigenetics & diabetes prone people, they found it took a few generations for the switch back to 'normal.'

Here's the thread:

What about those with the Huntington's gene or other dreaded genetic disorders? That can't really be switched off or can it? I'm curious.

You can turn off Genes by removing the allergen that turned it on. The popular name for it is "reversing" , as in reversing chronic disease. It's no myth. That's what I do.

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Status: Clear after 30 years. Wow, I guess it's been 6 years, now.

[ Story: Severe Acne since I was 10. 10+ years of Dermatologists, Antibiotics, topicals and ACCUTANE did nothing. Discovered oranges triggered the worst of my cystic acne = about 70% improvement. Tried some nutrient supplements like B-complex with zinc and C, saw palmetto and a BHA like the aspirin mask = more improvement, a lot less oily. Then, Diet changes = Clear.

Regimen: Anti-inflammatory, nutrient dense, blood sugar stabilizing diet and supplements (for hormones, inflammation, aging, health). No soap or other cleanser except for hand washing! Water only or Oil cleanse. Aloe Vera mixed with niacinimide and a high linoleic acid oil for moisturizer and reduce pigmentation.

Diet effects acne in so many ways: hormone balance, inflammation, Insulin levels, digestion, allergies and intolerances, liver function, adrenal function, SHBG levels, sebum quality, cell function and turnover, nutrient deficiencies, body fat, etc. Basic advice: Eat, sleep, supplement and exercise like you are a diabetic. And eat real food!

For more information, see my Good Things for Acne thread *Moderator edit - Please refer to the board rules (see “Advertising/soliciting”, “Linking” and “Signatures”)*

When you eat stuff, Stuff Happens!


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Everyone carries the "acne gene" , most people, however, do not encounter their trigger.

Maybe. Because the issue isn't necessarily the genes. Turns out after all the mapping was done, we don't have that many genes. It's the enzymes. And they are switched on and off by what you do to yourself or by what your parents did and then are passed down to you. In the study involving epigenetics & diabetes prone people, they found it took a few generations for the switch back to 'normal.'

Here's the thread:

What about those with the Huntington's gene or other dreaded genetic disorders? That can't really be switched off or can it? I'm curious.

You can turn off Genes by removing the allergen that turned it on. The popular name for it is "reversing" , as in reversing chronic disease. It's no myth. That's what I do.

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Everyone carries the "acne gene" , most people, however, do not encounter their trigger.

Maybe. Because the issue isn't necessarily the genes. Turns out after all the mapping was done, we don't have that many genes. It's the enzymes. And they are switched on and off by what you do to yourself or by what your parents did and then are passed down to you. In the study involving epigenetics & diabetes prone people, they found it took a few generations for the switch back to 'normal.'

Here's the thread:

What about those with the Huntington's gene or other dreaded genetic disorders? That can't really be switched off or can it? I'm curious.

You can turn off Genes by removing the allergen that turned it on. The popular name for it is "reversing" , as in reversing chronic disease. It's no myth. That's what I do.

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"Genetics load the gun, environment pulls the trigger"


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Everyone carries the "acne gene" , most people, however, do not encounter their trigger.

Maybe. Because the issue isn't necessarily the genes. Turns out after all the mapping was done, we don't have that many genes. It's the enzymes. And they are switched on and off by what you do to yourself or by what your parents did and then are passed down to you. In the study involving epigenetics & diabetes prone people, they found it took a few generations for the switch back to 'normal.'

Here's the thread:

What about those with the Huntington's gene or other dreaded genetic disorders? That can't really be switched off or can it? I'm curious.

You can turn off Genes by removing the allergen that turned it on. The popular name for it is "reversing" , as in reversing chronic disease. It's no myth. That's what I do.

There's not always an allergen. People develop things spontaneously for reasons unknown.

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Everyone carries the "acne gene" , most people, however, do not encounter their trigger.

Maybe. Because the issue isn't necessarily the genes. Turns out after all the mapping was done, we don't have that many genes. It's the enzymes. And they are switched on and off by what you do to yourself or by what your parents did and then are passed down to you. In the study involving epigenetics & diabetes prone people, they found it took a few generations for the switch back to 'normal.'

Here's the thread:

What about those with the Huntington's gene or other dreaded genetic disorders? That can't really be switched off or can it? I'm curious.

You can turn off Genes by removing the allergen that turned it on. The popular name for it is "reversing" , as in reversing chronic disease. It's no myth. That's what I do.

There's not always an allergen. People develop things spontaneously for reasons unknown.

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Everyone carries the "acne gene" , most people, however, do not encounter their trigger.

Maybe. Because the issue isn't necessarily the genes. Turns out after all the mapping was done, we don't have that many genes. It's the enzymes. And they are switched on and off by what you do to yourself or by what your parents did and then are passed down to you. In the study involving epigenetics & diabetes prone people, they found it took a few generations for the switch back to 'normal.'

Here's the thread:

What about those with the Huntington's gene or other dreaded genetic disorders? That can't really be switched off or can it? I'm curious.

You can turn off Genes by removing the allergen that turned it on. The popular name for it is "reversing" , as in reversing chronic disease. It's no myth. That's what I do.

There's not always an allergen. People develop things spontaneously for reasons unknown.

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today Putin is trying to steal our land! and no, i'm not referring to Crimea, but to a part of Moldova!


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Everyone carries the "acne gene" , most people, however, do not encounter their trigger.

Maybe. Because the issue isn't necessarily the genes. Turns out after all the mapping was done, we don't have that many genes. It's the enzymes. And they are switched on and off by what you do to yourself or by what your parents did and then are passed down to you. In the study involving epigenetics & diabetes prone people, they found it took a few generations for the switch back to 'normal.'

Here's the thread:

What about those with the Huntington's gene or other dreaded genetic disorders? That can't really be switched off or can it? I'm curious.

You can turn off Genes by removing the allergen that turned it on. The popular name for it is "reversing" , as in reversing chronic disease. It's no myth. That's what I do.

There's not always an allergen. People develop things spontaneously for reasons unknown.

That is according to our current healthcare system (which ranks 46th in the world by the way) to use as their excuse to push more meds so Doctors can keep that paycheck coming in from pharmaceutical companies.

When you break down what chronic diseases really are, you see what they really are. 2 main types... Autoimmune and inflammatory diseases. Doctors unwittingly gave us the cause of Autoimmune with what causes Celiac Disease and inflammation is an allergic reaction. It's really that simple.


"Genetics load the gun, environment pulls the trigger"


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You do know that the link between acid reflux and esophageal cancer is crystal clear? Now they linked acid reflux to throat and voice box cancers. Just like the link between thyroid disease and thyroid cancer.

People are reversing cancer by diet change alone. Why does that work? Because they are eliminating the allergen that is triggering the Gene that signals the immune response.

You can google that they say obese children are more likely to develop cancer than their non obese counter part. I reversed 2 out of 3 of those chronic diseases and Dr Osborne did the other by eliminating food allergies only.

Watch "Forks Over Knives" and you will here this from a biochemist and a few other Doctors. Or sit there and assume you are right and I'm wrong even though you have done nothing even close to what I have as well as others. You sound like the Dr's that said Celiac Disease was a European disease. Lol

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gahhhhhh....cancer is a result of a mutation in your DNA that causes your cells to grow and divide at rapid rates.

For example, certain types of skin cancer happen when UV rays change three nucleotides to three thymines in a row. This causes a break in the "ladder" of your DNA, and you can't create the proteins needed for normal cell growth. This is not an allergic reaction, and is also not caused by the unhealthy consumption of macromolecules. In fact, bacteria can get this mutation from UV rays...but I don't see them getting obese-- excessive nutrients are NOT the reason behind cancer.

Anyway...I believe we are getting WAAAY off topic from the original post.

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gahhhhhh....cancer is a result of a mutation in your DNA that causes your cells to grow and divide at rapid rates.

For example, certain types of skin cancer happen when UV rays change three nucleotides to three thymines in a row. This causes a break in the "ladder" of your DNA, and you can't create the proteins needed for normal cell growth. This is not an allergic reaction, and is also not caused by the unhealthy consumption of macromolecules. In fact, bacteria can get this mutation from UV rays...but I don't see them getting obese-- excessive nutrients are NOT the reason behind cancer.

Anyway...I believe we are getting WAAAY off topic from the original post.

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You do know that the link between acid reflux and esophageal cancer is crystal clear? Now they linked acid reflux to throat and voice box cancers. Just like the link between thyroid disease and thyroid cancer.

People are reversing cancer by diet change alone. Why does that work? Because they are eliminating the allergen that is triggering the Gene that signals the immune response.

You can google that they say obese children are more likely to develop cancer than their non obese counter part. I reversed 2 out of 3 of those chronic diseases and Dr Osborne did the other by eliminating food allergies only.

Watch "Forks Over Knives" and you will here this from a biochemist and a few other Doctors. Or sit there and assume you are right and I'm wrong even though you have done nothing even close to what I have as well as others. You sound like the Dr's that said Celiac Disease was a European disease. Lol

You're right up to the point where you claim that diet works because you're eliminating an allergen. Cancer is not an autoimmune disease and it does not result from food allergy, rather it results from lack of nutrition combined with an imbalance of macromolecular nutrients (too many carbohydrates). Yes, diet can fix it and/or prevent it. But this isn't the result of removing allergens, rather a result of obtaining the correct nutrition and removing agents that screw with metabolism or suppress the immune system.


"Genetics load the gun, environment pulls the trigger"


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umm... you did know Celiac Disease is also linked to cancer right? You also knew Celiac Disease is caused by an immune response to gluten I'm sure?

Allergens are what sets everything in motion.

Ps... the biochemist in "Forks Over Knives" grew up on a dairy farm and set out to show how good milk was for us. He learned just the opposite. Hence "Forks Over Knives".

pss... pay attention to some medication commercials, some tell you cancer can be an allergic reaction to the medication.

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umm... you did know Celiac Disease is also linked to cancer right? You also knew Celiac Disease is caused by an immune response to gluten I'm sure?

Allergens are what sets everything in motion.

Ps... the biochemist in "Forks Over Knives" grew up on a dairy farm and set out to show how good milk was for us. He learned just the opposite. Hence "Forks Over Knives".

pss... pay attention to some medication commercials, some tell you cancer can be an allergic reaction to the medication.

There are cases where immune reactions *can* lead to cancer, but this is in the extreme minority of cancers. Celiac being correlated with cancer is one case. The types of cancers celiacs are disposed to get are also extremely limited, I think to some lymphomas (probably because most of your immune system is situated around the digestive tract). Most cancers are not caused by immune reactions to an antigen.

In regards to medication, side effects can sometimes include cancer, but this is pretty much never due to allergic reaction; it's due to immune suppression.

But come on now, unless you want to deny that UV radiation causes mutations via T dimers which can lead to cancer, you can't make the claim that all cancers originate from an immune response, nevermind allergy.


"Genetics load the gun, environment pulls the trigger"


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gahhhhhh....cancer is a result of a mutation in your DNA that causes your cells to grow and divide at rapid rates.

For example, certain types of skin cancer happen when UV rays change three nucleotides to three thymines in a row. This causes a break in the "ladder" of your DNA, and you can't create the proteins needed for normal cell growth. This is not an allergic reaction, and is also not caused by the unhealthy consumption of macromolecules. In fact, bacteria can get this mutation from UV rays...but I don't see them getting obese-- excessive nutrients are NOT the reason behind cancer.

Anyway...I believe we are getting WAAAY off topic from the original post.

There are more ways than UV radiation to cause mutations in DNA. In fact, radiation is one of the less common causes of cancer, and is primarily restricted to skin cancer. Many more cancers arise from free radical reactions (a chain reaction in which an atom with a single unpaired electron can replace an atom with a full set of electrons, thus generating another radical). Free radicals are generated in a number of ways including smoking, radiation, and pollution, but they are primarily generated by our own metabolism (a side effect of the last step of the electron transport chain in which O2 becomes H2O). This is why our body makes a number of antioxidants, and why antioxidants are said to have cancer-preventative activities.

Even in conventional medicine, it has been clear for some time now that obesity and diabetes are correlated with increased cancer risk, as are smoking and excessive alcohol consumption.


Status: Clear after 30 years. Wow, I guess it's been 6 years, now.

[ Story: Severe Acne since I was 10. 10+ years of Dermatologists, Antibiotics, topicals and ACCUTANE did nothing. Discovered oranges triggered the worst of my cystic acne = about 70% improvement. Tried some nutrient supplements like B-complex with zinc and C, saw palmetto and a BHA like the aspirin mask = more improvement, a lot less oily. Then, Diet changes = Clear.

Regimen: Anti-inflammatory, nutrient dense, blood sugar stabilizing diet and supplements (for hormones, inflammation, aging, health). No soap or other cleanser except for hand washing! Water only or Oil cleanse. Aloe Vera mixed with niacinimide and a high linoleic acid oil for moisturizer and reduce pigmentation.

Diet effects acne in so many ways: hormone balance, inflammation, Insulin levels, digestion, allergies and intolerances, liver function, adrenal function, SHBG levels, sebum quality, cell function and turnover, nutrient deficiencies, body fat, etc. Basic advice: Eat, sleep, supplement and exercise like you are a diabetic. And eat real food!

For more information, see my Good Things for Acne thread *Moderator edit - Please refer to the board rules (see “Advertising/soliciting”, “Linking” and “Signatures”)*

When you eat stuff, Stuff Happens!


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try and spend some time reading up on food sensitivities and cancer. The amount of research done on this is mind blowing.

Gluten does not cause cancer. Chemicals do not cause cancer. They are not living, breathing, or moving. So how do you suppose they have direct links to cancer? If you or anybody else did any hands on research on what I'm claiming, you will come to the same conclusion everyone else like me came to.

Everyone here that disputes me is very knowledgeable in the functionality of diseases. Much more than I am. This is in part because I turned my focus to the root cause/origin. I have done hands on research on what I claim. I have reversed diseases that Americans spend millions on, live with, and die from. I read tons of research on this but I also didn't believe it until I did it for myself. I know it's hard to believe but this is what comes up every time researchers focus on food.

Ps... T. Colin Campbell got the chance of a lifetime to witness many chronic diseases (including cancer) develop in, for the most part, disease free people. He wrote about it. It's called The China Study.

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try and spend some time reading up on food sensitivities and cancer. The amount of research done on this is mind blowing.

Gluten does not cause cancer. Chemicals do not cause cancer. They are not living, breathing, or moving. So how do you suppose they have direct links to cancer? If you or anybody else did any hands on research on what I'm claiming, you will come to the same conclusion everyone else like me came to.

Everyone here that disputes me is very knowledgeable in the functionality of diseases. Much more than I am. This is in part because I turned my focus to the root cause/origin. I have done hands on research on what I claim. I have reversed diseases that Americans spend millions on, live with, and die from. I read tons of research on this but I also didn't believe it until I did it for myself. I know it's hard to believe but this is what comes up every time researchers focus on food.

Ps... T. Colin Campbell got the chance of a lifetime to witness many chronic diseases (including cancer) develop in, for the most part, disease free people. He wrote about it. It's called The China Study.

Chemicals do cause cancer. Why does something have to 'breathe' in order to cause cancer, in your mind? Everything just boils down to biochemistry at some point.

You can do mutagenesis assays to change DNA in a petri dish of cells without any immune system involvement. Take a bunch of skin cells, add your carcinogen, and voila, the normal epithelial cells transform into cancerous cells. I've worked in a lab that researched breast cancer, epigenetics, and the impact of diet on epigenetics. I have experience with these particular problems. I've done the hands on research you're urging me to do - not just pressing a few keywords into google and then finding what you want to find. There's plenty of misinformation to go around.

The China Study is often cited but ultimately proves nothing. It's a bunch of correlations between meat eating and cancer. I find it extremely unconvincing, in part because half of their conclusions simply do not make sense. An excerpt from wikipedia on their findings:

"They write that "eating foods that contain any cholesterol above 0 mg is unhealthy."[4] They also recommend adequate amounts of sunshine exposure or supplements to maintain adequate levels of vitamin D, and supplements of vitamin B12 in case of complete avoidance of animal products.[5]"

Supplementation in order to stay healthy? Avoidance of cholesterol? Sure. I wonder what the Masai would think. Regardless, the real problem is that the authors of the China Study draw very strong conclusions from correlations only without any reasonable intervention studies to indicate any causation whatsoever. In fact, it's probably more likely that the correlations they saw between animal products and disease were caused by industrial contamination or food source.

Finally, you might have 'cured' any number of diseases through dietary modification, but that doesn't mean that diet was curing the diseases in the way you think it was. I too believe that food is medicine, and diet has helped me greatly. However, suggesting that some things like cancer are caused by food allergies is absurd. Diet is the cause of many cancers; but it does not cause cancer via food allergies except in maybe 1 or 2 cases. Biochemistry is a lot more complicated than that.

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Diet is not the cause of *many* cancers, only about a handful of cancers are linked to diet and when then the evidence is still modest at best. The majority of cancers are largely unknown or associated with old age. Cancer has been around before man.

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"Genetics load the gun, environment pulls the trigger"


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Diet is not the cause of *many* cancers, only about a handful of cancers are linked to diet and when then the evidence is still modest at best. The majority of cancers are largely unknown or associated with old age. Cancer has been around before man.

90% of cancers are caused by environmental factors, while 10% are genetic (at most; some numbers are as low as 5%).

Of the 90% caused by environmental factors, a third are due to diet.

Here's a peer-reviewed paper from 2008 (on ncbi) just so you know I'm not pulling these numbers out of the air:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515569/

As an aside, age is often cited as a factor in the cause of cancer, but this isn't true. The effects of diet/smoking/etc add up over time, and so older individuals suffer more from cancer, but just being old - just time - is not sufficient to cause cancer on its own.

Edit: I think wikipedia sums it up nicely: http://en.wikipedia.org/wiki/Diet_and_cancer

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Diet is not the cause of *many* cancers, only about a handful of cancers are linked to diet and when then the evidence is still modest at best. The majority of cancers are largely unknown or associated with old age. Cancer has been around before man.

90% of cancers are caused by environmental factors, while 10% are genetic (at most; some numbers are as low as 5%).

Of the 90% caused by environmental factors, a third are due to diet.

Here's a peer-reviewed paper from 2008 (on ncbi) just so you know I'm not pulling these numbers out of the air:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515569/

As an aside, age is often cited as a factor in the cause of cancer, but this isn't true. The effects of diet/smoking/etc add up over time, and so older individuals suffer more from cancer, but just being old - just time - is not sufficient to cause cancer on its own.

Edit: I think wikipedia sums it up nicely: http://en.wikipedia.org/wiki/Diet_and_cancer


"Genetics load the gun, environment pulls the trigger"


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What's funny is what The China Study proposes is what I am finding through blood tests. The amount of people that test positive with a allergy to animal proteins is staggering. Also, you must not know the cause of high cholesterol or how to lower it without meds.

You act like you know more than the researchers that spent a lot of their lives studying this while knowing that there is no big payday except for saving lives in the future. Besides, there being no known cause is just laughable. Things don't just happen for know reason.

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What's funny is what The China Study proposes is what I am finding through blood tests. The amount of people that test positive with a allergy to animal proteins is staggering. Also, you must not know the cause of high cholesterol or how to lower it without meds.

You act like you know more than the researchers that spent a lot of their lives studying this while knowing that there is no big payday except for saving lives in the future. Besides, there being no known cause is just laughable. Things don't just happen for know reason.

Meh, I took the allergy tests and I was only sensitive to grains and legumes. Every kind of meat was fine. I know n=1, but I find your findings dubious. And please do enlighten me about the causes of high cholesterol; also let me know how you think cholesterol leads to heart disease, because cholesterol itself is not dangerous, something must happen to it first. Someone I am related to who is doing the paleo diet recently got their blood tested, and their total cholesterol levels were high - with lower than average LDL and much higher than average HDL. The doctor was quite surprised. He commented that these are the kinds of blood tests doctors usually see in people who will live to ninety or a hundred.

I'm a scientist. I'm not acting like I know more than those who studied this, I'm simply critiquing their work. It's easy to become wrapped up in your own work and not notice a host of flaws in your own data if you don't have people on the outside looking in and telling you where you're going wrong.


"Genetics load the gun, environment pulls the trigger"


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What's funny is what The China Study proposes is what I am finding through blood tests. The amount of people that test positive with a allergy to animal proteins is staggering. Also, you must not know the cause of high cholesterol or how to lower it without meds.

You act like you know more than the researchers that spent a lot of their lives studying this while knowing that there is no big payday except for saving lives in the future. Besides, there being no known cause is just laughable. Things don't just happen for know reason.

Meh, I took the allergy tests and I was only sensitive to grains and legumes. Every kind of meat was fine. I know n=1, but I find your findings dubious. And please do enlighten me about the causes of high cholesterol; also let me know how you think cholesterol leads to heart disease, because cholesterol itself is not dangerous, something must happen to it first. Someone I am related to who is doing the paleo diet recently got their blood tested, and their total cholesterol levels were high - with lower than average LDL and much higher than average HDL. The doctor was quite surprised. He commented that these are the kinds of blood tests doctors usually see in people who will live to ninety or a hundred.

I'm a scientist. I'm not acting like I know more than those who studied this, I'm simply critiquing their work. It's easy to become wrapped up in your own work and not notice a host of flaws in your own data if you don't have people on the outside looking in and telling you where you're going wrong.

>>Wrong. Many cancers are unknown (idiopathic) this is not the same as genetic and environmental either. Only one third of cancers is associated with lifestyle abuse and environment, fewer than that is inherited (2%-5%) and the rest are generally unknown. Anyone can get cancer, even the healthiest eaters and those that abstain from poor lifestyle choices. The disease knows no discrimination. There are so many diseases under the umbrella term "cancer: it's impossible to protect yourself from all of them as many do not need a cause to occur.

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