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How Long For Nizoral Shampoo [Ketoconazole] To Work And Is Initial Breakout Possible?

nizoral ketoconazole dht sedum acne initial breakout

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#1 Riddled



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Posted 07 November 2013 - 04:59 PM

Hi, as per title:


If you have taken Nizoral shampoo [ketoconazole] how long did it take to work before you started to notice an improvement with your acne?


Did you have an initial breakout?

Do you think an initial breakout would be possible from Nizoral considering what ever the mechanisms are that help with acne etc.




#2 Tom Busby

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Posted 08 November 2013 - 09:49 AM

Nizoral shampoo treats the red bumps and white flakes induced by malassezia yeast.  Nizoral doesn't treat acne, although both conditions create a similar appearance.  The difference is that the red bumps induced by malassezia do not involve comedones, and you'll notice you have a lot of dandruff (previously invisible white flakes) once you start using Nizoral. 


The active ingredient in Nozoral is ketoconanzole, which is somewhat effective, but climbazole is more effective as an active ingredient, and I suggest looking for Hegor 150 climbazole shampoo, which is available on eBay.  Ketoconazole and climbazole slowly dissolve the fungal cell walls, but the yeast's hyphae stage creates a biofilm that is difficult to dissolve, so the treatment takes several months -- up to a year -- and you need to use antifungal products on a daily basis afterward.


You'll experience what appears to be an initial breakout when you begin to use an antifungal, because the biofilm had previously prevented your immune system from recognizing the fungal invader, until the fungal cells walls start to dissolve.  That's why you'll notice more red bumps rather than fewer, when you first begin using an antifungal.  Hang in there, and do not be dismayed.

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