I have adult hormonal acne and have been on and off Monodox for four or five months, with interludes to take Bactrim (ugh) and now Doryx but Monodox eventually lost its efficacy.
When it worked, I immediately noticed a decrease in inflammation/hypigmentation, the suppression of my usual cheek papules/cysts, but lots of little whiteheads on my chin. Then, after a month or so, for the first time in years, I had 80% clear, even-toned skin.
It stopped working two weeks later (that is, maybe six to ten weeks after I started it) and the discoloration/cheek cysts re-emerged. I tried Bactrim and it did nothing, so I went back on Monodox for a month. Same thing--clear skin for a while then seeming loss of efficacy. Now I'm on Doryx and what I'm seeing is even worse than what I did when I tried Bactrim--I feel like I'm purging. Also, my hair is disgustingly greasy/limp all the time, which definitely doesn't help. I don't understand, considering Monodox and Doryx have the same drug.
I realize I've probably built up resistance to antibiotics...?
Can you purge on an antibiotic? Why was the Monodox so effective while the other antibiotics seem to do nothing, and what can I do?
(Regarding what else I've tried--Ive tried aldactone and it was horrible for me; Solodyn had horrible side effects; I'm terrified of going on birth control; and I'm probably going to go back on Accutane, but while I wait for that, I need to figure out if I should just use up my Monodox prescription.)
Acne has controlled my life for the past ten years and I'm sick and tired of it.